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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Fawzy, Amr
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (23/23 displayed)
- 2024Effect of inositol hexaphosphate acid versus polyacrylic acid on dentin properties and adhesion of a self-adhesive restorative material to dentincitations
- 2024The Synergistic Effect of High Intensity Focused Ultrasound on In-vitro Remineralization of Tooth Enamel by Calcium Phosphate Ion Clusterscitations
- 2024Flowable resin-based composites modified with chlorhexidine-loaded mesoporous silica nanoparticles induce superior antibiofilm properties
- 2022Cytotoxicity and antimicrobial efficiency of ZrO2 nanoparticles reinforced 3D printed resinscitations
- 2022Development of 3D printed dental resin nanocomposite with graphene nanoplatelets enhanced mechanical properties and induced drug-free antimicrobial activity.citations
- 2021Development of 3D printed resin reinforced with modified ZrO2 nanoparticles for long-term provisional dental restorationscitations
- 2021Formulation of pH-sensitive chlorhexidine-loaded/mesoporous silica nanoparticles modified experimental dentin adhesivecitations
- 2020The Effect of Cross-linking Efficiency of Drug-Loaded Novel Freeze Gelated Chitosan Templates for Periodontal Tissue Regenerationcitations
- 2020Effect of acid etching on dentin bond strength of ultra-mild self-etch adhesivescitations
- 2020Properties of a modified quaternary ammonium silane formulation as a potential root canal irrigant in endodonticscitations
- 2020In vitro bonding performance of modern self-adhesive resin cements and conventional resin-modified glass ionomer cements to prosthetic substratescitations
- 2019Resin-based dental composites for tooth filling
- 2019Macrophage response and surface analysis of dental cementum after treatment with high intensity focused ultrasoundcitations
- 2019An in vitro study of a novel quaternary ammonium silane endodontic irrigantcitations
- 2019Co-blend application mode of bulk fill composite resincitations
- 2018In vitro assessment of ribose modified two-step etch-and-rinse dentine adhesivecitations
- 2017Proanthocyanidins-Loaded Nanoparticles Enhance Dentin Degradation Resistancecitations
- 2017Potentiating the antibacterial effect of silver nanospheres by surface-capping with chlorhexidine gluconatecitations
- 2015Characterization of antibacterial and adhesion properties of chitosan-modified glass ionomer cementcitations
- 2012Riboflavin as a dentin crosslinking agentcitations
- 2009Effect acidic and alkaline/heat treatments on the bond strength of different luting cements to commercially pure titaniumcitations
- 2009Tensile bond strength of immediately repaired anterior microfine hybrid restorative composite using nontrimmed hourglass specimens
- 2008Effect of surface treatments on the tensile bond strength of repaired water-aged anterior restorative micro-fine hybrid resin compositecitations
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article
The Synergistic Effect of High Intensity Focused Ultrasound on In-vitro Remineralization of Tooth Enamel by Calcium Phosphate Ion Clusters
Abstract
<p>Background: Remineralization of dental enamel is an important intervention strategy for the treatment of demineralized lesions. Existing approaches have limitations such as failure to adequately reproduce both the ideal structural and mechanical properties of the native tooth. The ability of ultrasound to control and accelerate the crystallization processes has been widely reported. Therefore, a new approach was explored for in-vitro enamel remineralization involving the synergistic effect of high-intensity focused ultrasound (HIFU) coupled with calcium phosphate ion clusters (CPICs). Methods: The demineralized enamel was treated with CPICs, with or without subsequent HIFU exposure for different periods (2.5, 5, and 10 min). The specimens were characterized by scanning electron microscopy (SEM), atomic force microscopy (AFM), and Raman spectroscopy. The surface hardness and crystallographic properties of the treated specimens were evaluated using Vickers microhardness testing and X-ray diffraction (XRD), respectively. Results: SEM revealed distinct, organized, and well-defined prismatic structures, showing clear evidence of remineralization in the combined CPIC/HIFU treatment groups. AFM further revealed a decrease in the surface roughness values with increasing HIFU exposure time up to 5 min, reflecting the obliteration of interprismatic spaces created during demineralization. The characteristic Raman band at 960 cm-1 associated with the inorganic phase of enamel dominated well in the HIFU-treated specimens. Importantly, microhardness testing further demonstrated that new mineral growth also recovered the mechanical properties of the enamel in the HIFU-exposed groups. Critical to our aspirations for developing this into a clinical process, these results were achieved in only 5 min. Conclusion: HIFU exposure can synergise and significantly accelerate in-vitro enamel remineralization process via calcium phosphate ion clusters. Therefore, this synergistic approach has the potential for use in future clinical interventions.</p>