| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Song, Y.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (14/14 displayed)
- 2021Effect of sub-boundaries on primary spacing dynamics during 3D directional solidification conducted on DECLIC-DSIcitations
- 2018Thermal-field effects on interface dynamics and microstructure selection during alloy directional solidificationcitations
- 2018Enhancement of surface bioactivity on carbon fiber-reinforced polyether ether ketone via graphene modification.citations
- 2017Convection Effects During Bulk Transparent Alloy Solidification in DECLIC-DSI and Phase-Field Simulations in Diffusive Conditionscitations
- 2017Evolution of Primary Spacing during Directional Solidification of Transparent Bulk Samples Conducted on DECLIC-DSI
- 2017Experimental observation of oscillatory cellular patterns in three-dimensional directional solidificationcitations
- 2016Three-dimensional grain boundary instability and solitary cell dynamics in directional solidification of binary alloys
- 2016Phase-field modeling of cellular and dendritic microstructure formation: dynamical selection of the primary spacing
- 2016Dynamics of Microstructure Formation in 3D Directional Solidification of Transparent Model Alloys under Microgravity: Analysis of the Primary Spacing Evolution
- 2016Toughening of carbon fibre reinforced polymer composites with nano rubber for advanced industrial applicationscitations
- 2011Combining stereo and time-of-flight images with application to automatic plant phenotypingcitations
- 2011Combining stereo and time-of-flight images with application to automatic plant phenotypingcitations
- 2005Selective fluorescence detection of divalent and trivalent metal ions with functionalized lipid membranescitations
- 2000Osteogenic protein 1 device stimulates bone healing to hydroxyapaptite-coated and titanium implants
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article
Enhancement of surface bioactivity on carbon fiber-reinforced polyether ether ketone via graphene modification.
Abstract
<h4>Background and objective</h4>The modulus of carbon fiber-reinforced polyether ether ketone (CFR-PEEK), a composite containing layers of carbon fiber sheets, can be precisely controlled to match bone. However, CFR-PEEK is biologically inert and cannot promote bone apposition. The objective of this study was to investigate whether graphene modification could enhance the bioactivity of CFR-PEEK.<h4>Methods and results</h4>In vitro, the proliferation and differentiation of rat bone marrow stromal cells on scaffolds were quantified via cell-counting kit-8 assay and Western blotting analysis of osteoblast-specific proteins. Graphene modification significantly promoted bone marrow stromal cell proliferation and accelerated induced differentiation into osteogenic lineages compared to cells seeded onto nongraphene-coated CFR-PEEK. An in vivo rabbit extraarticular graft-to-bone healing model was established. At 4, 8, and 12 weeks after surgery, microcomputed tomography analyses and histological observations revealed significantly better microstructural parameters and higher average mineral apposition rates for graphene-modified CFR-PEEK implants than CFR-PEEK implants (<i>P</i><0.05). van Gieson staining indicated more new bone was formed around graphene-modified CFR-PEEK implants than CFR-PEEK implants.<h4>Conclusion</h4>Graphene may have considerable potential to enhance the bioactivity and osseointegration of CFR-PEEK implants for clinical applications.