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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Nowicki, Marek
Adam Mickiewicz University in Poznań
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (16/16 displayed)
- 2023Metallodendrimers Unveiled: Investigating the Formation and Features of Double-Decker Silsesquioxane-Based Silylferrocene Dendrimerscitations
- 2022Novel Mesoporous Organosilicas with Task Ionic Liquids: Properties and High Adsorption Performance for Pb(II)citations
- 2019Recovery from bone loss, diminished mineral density and strength in mice after treatment with steroidal and nonsteroidal anti-inflammatory drugs by injection of exosomes enriched with agomir miRNAs
- 2018Polydopamine grafted on an advanced Fe <inf>3</inf> O <inf>4</inf> /lignin hybrid material and its evaluation in biosensingcitations
- 2018Characterization of polymer inclusion membranes (PIM) containing phosphonium ionic liquids and their application for separation of Zn(II) from Fe(III)citations
- 2017Lipase B from candida Antarctica immobilized on a silica-lignin matrix as a stable and reusable biocatalytic systemcitations
- 2015Chemical etching of stainless steel 301 for improving performance of electrochemical capacitors in aqueous electrolytecitations
- 2015Synergistic effect of modified natural fibres with halogen-free fire retardants in reducing flammability of compositescitations
- 2014Morphology and magnetic properties of Fe<inf>3</inf>O<inf>4</inf>-alginic acid nanocomposites
- 2013Synthesis and characterization of modified cellulose acetate propionate nanocomposites via sol-gel processcitations
- 2013Cellulose acetate butyrate nanocomposites synthesized via sol-gel methodcitations
- 2008A nanoindentation study of photo-induced changes in polymers containing azobenzenecitations
- 2006Nanomechanical measurements on glutamine molecularly imprinted nylon filmscitations
- 2003Nanoscale mechanical properties of polymers irradiated by UVcitations
- 2002Polymer studies using Atomic Force Microscopy (AFM). Part I. Principles of AFM and its application in polymer morphology investigationscitations
- 2000Effect of heat treatment on phase behaviour and molecular dynamics of mineral-filled PPScitations
Places of action
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article
Recovery from bone loss, diminished mineral density and strength in mice after treatment with steroidal and nonsteroidal anti-inflammatory drugs by injection of exosomes enriched with agomir miRNAs
Abstract
<jats:p>The project “Recovery from bone loss, diminished mineral density and strength in mice after treatment with steroidal and nonsteroidal anti-inflammatory drugs by injection of exosomes enriched with agomir miRNAs” is an animal experiment project, and an attempt to apply small RNA strands to reverse the harmful effects of anti-inflammatory drugs. Patients chronically treated with an anti-inflammatory drug suffer from musculoskeletal side effects, including reversed mineralisation and disabled bone fracture healing. The aims of the study are to measure changes in bone mineral density and bone strength in mice treated with methylprednisolone or diclofenac in combination with treadmill exercise. The reversal of the negative effects of these drugs will be assayed using modified miRNA agomir. Bones obtained from the treated mice will be analysed using micro-CT, dynamic mechanical analysis (DMA), nanoindentation, Raman spectroscopy and gene expression. We expect to find specific miRNA counteracting the demineralisation of the mice bones caused by methylprednisolone or diclofenac.</jats:p>