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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Kojić, Vesna
Oncology Institute of Vojvodina
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (16/16 displayed)
- 2024Electrochemically synthesized biomaterials
- 2024Electrochemically synthesized biocomposite poly(vinyl alcohol)/chitosan-based coatings for medical applications
- 2023Enhanced antimicrobial properties and bioactivity of 3D-printed titanium scaffolds by multilayer bioceramic coating for large bone defectscitations
- 2023Single-step, electrophoretically deposited hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coating for biomedical applicationscitations
- 2023Ultrafine-grained microstructure effect on the biomedical Ti-based alloy performance
- 2023Laser-modified Ti-45Nb alloy’s response to bio-environment
- 2023Hydroxyapatite/poly(vinyl alcohol)/chitosan coating with gentamicin for orthopedic implantscitations
- 2022Silver Nanoparticles-Loaded Poly(Vinyl Alcohol)/Chitosan/Graphene Hydrogels Obtained by Electrochemical Synthesis
- 2021Microstructural refinement influence on the Ti-45Nb alloy properties in physiological conditions ; Uticaj usitnjavanja mikrostrukture na svojstva Ti-45Nb legure u fiziološkim uslovima
- 2020Electrophoretically Deposited Bioceramic Composite Coatings on Ti Substrate Intended for Medical Use
- 2019Mg/Cu co-substituted hydroxyapatite – Biocompatibility, mechanical properties and antimicrobial activitycitations
- 2019Gentamicin-loaded bioceramic composite coating aimed for biomedical use
- 2018Bioactive Hydroxyapatite/Chitosan/Gentamicin Composite Coating Electrodeposited on Titanium
- 2018Selective anticancer activity of hydroxyapatite/chitosan-poly(D,L)-lactide-co-glycolide particles loaded with an androstane-based cancer inhibitorcitations
- 2018Selective anticancer activity of hydroxyapatite/chitosan-poly(D,L)-lactide-co-glycolide particles loaded with an androstane-based cancer inhibitorcitations
- 2018Improvement of Biocompatibility by Formation of Nanotubular Oxide Layer on the Ultrafine Grained Ti-13Nb-13Zr Alloy
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article
Single-step, electrophoretically deposited hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coating for biomedical applications
Abstract
<jats:p>Biocomposite hydroxyapatite/poly(vinyl alcohol)/chitosan/gentamicin coatings were fabricated on titanium by electrophoretic deposition process (EPD) from an aqueous suspension using the constant voltage method. Characterization of the deposited coatings was performed by scanning electron microscopy with field emission (FE–SEM), Fourier transform infrared spectroscopy (FT–IR) and X-ray diffraction (XRD) after immersion in simulated body fluid (SBF) at 37 °C. The concentration of the released gentamicin was determined using a high-performance liquid chromatography (HPLC) coupled with a mass spectrometer (MS). The release profile confirmed an initial “burst-release effect” with ~ 30% of gentamicin released in the first 48 h, which could be of assistance in the prevention of biofilm formation. Antibacterial activity was proven by the agar diffusion method on Staphylococcus aureus TL and Escherichia coli ATCC 25922 bacterial strains. Cytotoxicity was tested by the dye exclusion test (DET) on MRC-5 and L929 fibroblast cell lines, with both coatings expressing nontoxicity. The results showed the high applicability potential of a poly(vinyl alcohol)-based biocomposite coating for medical purposes.</jats:p>