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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Ferreira, Mm
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (10/10 displayed)
- 2022Effect of Different Cavity Disinfectants on Adhesion to Dentin of Permanent Teethcitations
- 2022Evaluation of the Sealing Ability and Bond Strength of Two Endodontic Root Canal Sealers: An In Vitro Studycitations
- 2021Effect of Cavity Disinfectants on Adhesion to Primary Teeth-A Systematic Reviewcitations
- 2021Mechanical Characterization of Two Dental Restorative Materials after Acidic Challengecitations
- 2021The Influence of Irrigation during the Finishing and Polishing of Composite Resin Restorations-A Systematic Review of In Vitro Studiescitations
- 2021Mechanical and Tribological Characterization of a Bioactive Composite Resincitations
- 2021Aesthetic restoration of posterior teeth using different occlusal matrix techniquescitations
- 2020Mechanical and Tribological Characterization of a Dental Ceromercitations
- 2015Roughness and microhardness of composites after different bleaching techniquescitations
- 2015Effects on gastric mucosa induced by dental bleaching - an experimental study with 6% hydrogen peroxide in ratscitations
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article
Effects on gastric mucosa induced by dental bleaching - an experimental study with 6% hydrogen peroxide in rats
Abstract
The value of aesthetic dentistry has precipitated several developments in the investigation of dental materials related to this field The free marketing of these products is a problem and it is subject to various interpretations regarding its legality. There are several techniques for tooth whitening, the most used one being the external bleaching. It is the later version of such technique that poses the greatest danger of ingesting the product. The present study analysed the systemic effect of these products when they are swallowed. Objective: This experimental study aimed to observe the effects of a tooth whitening product, whose active agent is 6% hydrogen peroxide, on the gastric mucosa of healthy and non-tumour gastric pathology animals. Material and Methods: Fifty Wistar-Han rats were used and then distributed into 5 groups, one for control and four test groups in which the bleaching product was administered in animals with and without non-tumour gastric pathology (induced by the administration of 1 sample of 50% ethanol and 5% of drinking water during 6 days) at different times of study by gavage. There was a decrease in body weight in animals of groups handled during the study period, which was most pronounced in IV and VA groups. Changes in spleen weight relative to body weight revealed no statistically significant changes. An analysis of the frequency was performed on the results of macroscopic observation of the gastric mucosa. Results: The gastric mucosa revealed lesions in all manipulated groups, being more frequent in groups III and IV. It appears that there is a synergism when using hydrogen peroxide and 50% ethanol in the same group. Conclusion: Therefore, it seems that there are some signs of toxicity 3 to 4 days after administration of 6% hydrogen peroxide. The prescription of these therapies must be controlled by the clinician and the risks must be minimized.