| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Akhtar, Riaz
University of Liverpool
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (14/14 displayed)
- 2022Ligament mechanics of ageing and osteoarthritic human kneescitations
- 2018Facile production of nanocomposites of carbon nanotubes and polycaprolactone with high aspect ratios with potential applications in drug deliverycitations
- 2017Dual-stimuli responsive injectable microgel/solid drug nanoparticle nanocomposites for release of poorly soluble drugscitations
- 2016A pilot study of scanning acoustic microscopy as a tool for measuring arterial stiffness in aortic biopsiescitations
- 2015Using intermolecular interactions to crosslink PIM- 1 and modify its gas sorption properties
- 2015Using intermolecular interactions to crosslink PIM-1 and modify its gas sorption propertiescitations
- 2015Biomechanical Changes of Collagen Cross-Linking on Human Keratoconic Corneas Using Scanning Acoustic Microscopy.citations
- 2014Biomechanical changes after repeated collagen cross-linking on human corneas assessed in vitro using scanning acoustic microscopycitations
- 2013Biomechanical properties of human corneas following low- and high-intensity collagen cross-linking determined with scanning acoustic microscopycitations
- 2013Scanning acoustic microscopy for mapping the microelastic properties of human corneal tissuecitations
- 2012Multi-layer phase analysis: Quantifying the elastic properties of soft tissues and live cells with ultra-high-frequency scanning acoustic microscopycitations
- 2011Quantifying micro-mechanical properties of soft biological tissues with scanning acoustic microscopycitations
- 2008Mapping the Micromechanical Properties of Cryo-sectioned Aortic Tissue with Scanning Acoustic Microscopycitations
- 2008Nanoindentation of histological specimens using an extension of the Oliver and Pharr methodcitations
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document
Quantifying micro-mechanical properties of soft biological tissues with scanning acoustic microscopy
Abstract
In this study we have established a new approach to more accurately map acoustic wave speed (which is a measure of stiffness) within soft biological tissues at micrometer length scales using scanning acoustic microscopy. By using thin (5 μm thick) histological sections of human skin and porcine cartilage, this method exploits the phase information preserved in the interference between acoustic waves reflected from the substrate surface as well as internal reflections from the acoustic lens. A stack of images were taken with the focus point of acoustic lens positioned at or above the substrate surface, and processed pixel by pixel using custom software developed with LABVlEW and IMAQ (National Instruments) to extract phase information. Scanning parameters, such as acoustic wave frequency and gate position were optimized to get reasonable phase and lateral resolution. The contribution from substrate inclination or uneven scanning surface was removed prior to further processing. The wave attenuation was also obtained from these images. © 2011 Materials Research Society.