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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Ferreira, Isabel
Universidade Nova de Lisboa
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (45/45 displayed)
- 2023Amorphous carbon thin filmscitations
- 2023A facile blow spinning technique for green cellulose acetate/polystyrene composite separator for flexible energy storage devicescitations
- 2022Drug Delivery from PCL/Chitosan Multilayer Coatings for Metallic Implantscitations
- 2020Conductive electrospun Polyaniline/Polyvinylpyrrolidone nanofibers: Electrical and morphological characterization of new yarns for electronic textilescitations
- 2020Conductive electrospun Polyaniline/Polyvinylpyrrolidone nanofibers: Electrical and morphological characterization of new yarns for electronic textilescitations
- 2019Synthesis of thermoelectric magnesium-silicide pastes for 3D printing, electrospinning and low-pressure spraycitations
- 2019Graphene oxide-reinforced aluminium-matrix nanostructured composites fabricated by accumulative roll bondingcitations
- 2017Improved thermoelectric properties of nanocrystalline hydrogenated silicon thin films by post-deposition thermal annealingcitations
- 2017New composite of natural hydraulic lime mortar with graphene oxidecitations
- 2017Optimization of Cuprous Oxides Thin Films to be used as Thermoelectric Touch Detectorscitations
- 2016Vanadium Pentoxide Alloyed with Graphite for Thin-Film Thermal Sensorscitations
- 2016Thermal and magnetic properties of chitosan-iron oxide nanoparticlescitations
- 2016Natural Nanofibres for Composite Applicationscitations
- 2016V2O5 Thin Films for Flexible and High Sensitivity Transparent Temperature Sensorcitations
- 2015Hydrogenated nanocrystalline silicon thin films with promising thermoelectric propertiescitations
- 2014Al-doped ZnO nanostructured powders by emulsion detonation synthesis - Improving materials for high quality sputtering targets manufacturingcitations
- 2014Broadband photocurrent enhancement in a-Si:H solar cells with plasmonic back reflectorscitations
- 2014Nanostructured p-type Cr/V2O5 thin films with boosted thermoelectric propertiescitations
- 2014Effects of surfactants on the magnetic properties of iron oxide colloidscitations
- 2013Ab initio calculations and measurements of thermoelectric properties of V2O5 filmscitations
- 2012Aluminum doped zinc oxide sputtering targets obtained from nanostructured powders: Processing and applicationcitations
- 2012Thermoelectric transport in V2O5 thin filmscitations
- 2011Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetescitations
- 2011Away from silicon era: the paper electronicscitations
- 2009Zinc oxide, a multifunctional material: from material to device applicationscitations
- 2008The effects of ZnO coating on the photoluminescence properties of porous silicon for the advanced optoelectronic devicescitations
- 2008Investigation of hydrocarbon coated porous silicon using PECVD technique to detect CO2 gas
- 2008Highly stable transparent and conducting gallium-doped zinc oxide thin films for photovoltaic applicationscitations
- 2007Effect of polymer strengtheners on the local environment of biocompatible glass as probed by fluorescencecitations
- 2006Electron transport and optical characteristics in amorphous indium zinc oxide filmscitations
- 2006The study of high temperature annealing of a-SiC:H films
- 2006Multifunctional Thin Film Zinc Oxide Semiconductors: Application to Electronic Devicescitations
- 2006Characterization of nanocrystalline silicon carbide filmscitations
- 2006Electrical properties of amorphous and nanocrystalline hydrogenated silicon films obtained by impedance spectroscopycitations
- 2006Performances of an in-line PECVD system used to produce amorphous and nanocrystalline silicon solar cellscitations
- 2005Role of buffer layer on the performances of amorphous silicon solar cells with incorporated nanoparticles produced by plasma enhanced chemical vapor deposition at 27.12 MHzcitations
- 2005Study of a-SiC : H buffer layer on nc-Si/a-Si : H solar cells deposited by PECVD technique.citations
- 2004Characterization of silicon carbide thin films prepared by VHF-PECVD technologycitations
- 2004Batch processing method to deposit a-Si
- 2002Metal-ferroelectric thin film devicescitations
- 2002Structural characterisation of NiTi thin film shape memory alloyscitations
- 2002Influence of hydrogen gas dilution on the properties of silicon-doped thin films prepared by the hot-wire plasma-assisted technique
- 2001Thin film metal oxide semiconductors deposited on polymeric substrates
- 2001Thin film position sensitive detectors based on pin amorphous silicon carbide structurescitations
- 2001Nanocrystalline p-type silicon films produced by hot wire plasma assisted techniquecitations
Places of action
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article
Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes
Abstract
Objective: Metformin has been reported to reduce alpha-dicarbonyls, which are known to contribute to diabetic complications. It is unclear whether this is due to direct quenching of alpha-dicarbonyls or to an improvement in glycemic control. We therefore compared the effects of metformin versus repaglinide, an antihyperglycemic agent with an insulin-secreting mechanism, on the levels of the alpha-dicarbonyl 3-deoxyglucosone (3DG). Methods: We conducted a single-center, double-masked, double-dummy, crossover study involving 96 nonobese patients with type 2 diabetes. After a 1-month run-in on diet-only treatment, patients were randomized to either repaglinide (6 mg daily) followed by metformin (2 g daily) or vice versa each during 4 months with a 1-month washout between interventions. Results: 3DG levels decreased after both metformin (-19.3% (95% confidence interval (CI): -23.5, -14.8)) and repaglinide (-20.8% (95% CI: -24.9, -16.3)) treatments, but no difference was found between treatments (1.8% (95% CI: -3.8, 7.8)). Regardless of the treatment, changes in glycemic variables were associated with changes in 3DG. Specifically, 3DG decreased by 22.7% (95% CI: 19.0, 26.5) per S. D. decrease in fasting plasma glucose (PG), by 20.0% (95% CI: 16.2, 23.9) per S. D. decrease in seven-point mean plasma glucose, by 22.5% (95% CI: 18.6, 26.6) per S. D. decrease in area under the curve for PG, by 17.2% (95% CI: 13.8, 20.6) per S. D. decrease in HbAlc, and by 10.9% (95% CI: 6.4, 15.5) per S. D. decrease in Amadori albumin. In addition, decreases in 3DG were associated with decreases in advanced glycation endproducts and endothelial markers. Conclusion: Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in 3DG levels in nonobese individuals with type 2 diabetes. This may constitute a shared metabolic pathway through which both treatments have a beneficial impact on the cardiovascular risk.