| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Seitz, Hermann
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (20/20 displayed)
- 2024Quantitative Macromolecular Modeling Assay of Biopolymer-Based Hydrogelscitations
- 2024Direct ink writing of highly loaded polycaprolactone-barium titanate/bioactive glass composites for osteochondral tissue engineering
- 2023Piezoelectric and bioactive composites: Functional materials for bone tissue engineering
- 20223D printed gelatin/decellularized bone composite scaffolds for bone tissue engineering: Fabrication, characterization and cytocompatibility studycitations
- 2022A novel approach to fabricate load-bearing Ti6Al4V-Barium titanate piezoelectric bone scaffolds by coupling electron beam melting and field-assisted sintering
- 2022The influence of PEGDA’s molecular weight on its mechanical properties in the context of biomedical applicationscitations
- 2021Rapid tooling for micro injection molding of micro medical devices via digital light processing
- 20213D printing of biodegradable poly(L-lactide)/hydroxyapatite composite by composite extrusion modeling
- 2021Heat accumulation during femtosecond laser treatment at high repetition rate – A morphological, chemical and crystallographic characterization of self-organized structures on Ti6Al4V
- 2021Tunable Pseudo-Piezoelectric Effect in Doped Calcium Titanate for Bone Tissue Engineering
- 20203D Printing of Piezoelectric Barium Titanate-Hydroxyapatite Scaffolds with Interconnected Porosity for Bone Tissue Engineeringcitations
- 2020Sintering behavior of 3D printed barium titanate composite scaffolds for bone repair
- 2020PEGDA drug delivery scaffolds manufactured with a novel hybrid AM process
- 20203D printing of frames for anti-coronavirus face shields using different processes and materials
- 20193D-printed PEGDA structure with multiple depots for advanced drug delivery systems
- 2019A Novel Hybrid Additive Manufacturing Process for Drug Delivery Systems with Locally Incorporated Drug Depots. citations
- 2019Thermomechanical properties of PEGDA in combination with different photo-curable comonomerscitations
- 20193D printing of smart materials for bone regeneration
- 2018Thermomechanical properties of PEGDA and its co-polymerscitations
- 2007Non-toxic flexible photopolymers for medical stereolithography technologycitations
Places of action
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article
Thermomechanical properties of PEGDA in combination with different photo-curable comonomers
Abstract
<jats:title>Abstract</jats:title><jats:p>The technology of pharmaceutical drug delivery systems (DDS) as an individual and adjustable tool for drug administration has been intensively developed in the last years. Additive manufacturing (AM) techniques, such as stereolithography, are a promising approach towards DDS scaffold manufacturing. Stereolithography, by using layerby- photo-polymerisation, creates DDS scaffolds with highly controlled 3D geometry. Combined with inkjet printing it allows a very precise positioning of the drug depot in the basic scaffold and therefore also a better control of the drug release. Furthermore, this hybrid AM technique also allows for the creation of a multi-drug DDS with a several drug depots localized in desired positions within the scaffold. Determination of the scaffold and drug depot material properties is one of the initial steps for such novel DDS development. Basic characteristics, such as stiffness, elasticity or glass transition temperature (T<jats:sub>g</jats:sub>), are important for designing and adapting the material for biomedical application. The photosensitive poly(ethylene glycol) diacrylate (PEGDA) can be easily formed into a desired biocompatible scaffold geometry via stereolithography. In this study we have focused on the evaluation of PEGDA (Mn=700 g/mol) as a pure and copolymer system in combination with other acrylates (butanediol diacrylate, pentaerythritol triacrylate) as possible materials for DDS using this novel hybrid AM technique. Irgacure 2959, a biocompatible photoinitiator (PI), was used as a radical starter for photopolymerisation. Samples varying in PI and coacrylate concentration were prepared by conventional photopolymerisation. Physico-chemical analyses of the samples were performed and several parameters, such as stiffness, elongation at break and glass transition temperatures, were determined.</jats:p>