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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Schmitz, Klaus-Peter
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (8/8 displayed)
- 2021Polymer selection for Eustachian tube stent application based on mechanical, thermal and degradation behavior
- 2021Fiber composite materials via coaxial, dual or blend electrospinningcitations
- 2021A hydrogel based quasi-stationary test system for in vitro dexamethasone release studies for middle ear drug delivery systems
- 2019Numerical simulation of the functionality of a stent structure for venous valve prosthesescitations
- 2018Development of biodegradable stents for the treatment of Eustachian tube dysfunctioncitations
- 2017Investigation of Bauschinger effect in thermo-plastic polymers for biodegradable stents
- 2017Influence of bulk incorporation of FDAc and PTX on polymer propertiescitations
- 2016Conversion of engineering stresses to Cauchy stresses in tensile and compression tests of thermoplastic polymerscitations
Places of action
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article
Development of biodegradable stents for the treatment of Eustachian tube dysfunction
Abstract
<jats:title>Abstract</jats:title><jats:p>To provide an effective and safe therapy for chronic Eustachian tube dysfunction (ETD), biodegradable stents should be developed to restore important functions, e.g. middle ear ventilation and drainage. After defining general requirements specifications, stent designs of cardiovascular polymeric stents were modified according to dimensions and conditions of the Eustachian tube. Finite element simulations demonstrated the crimping capacity of the developed stent design and the ability of expansion in the specific geometry of the target location. Subsequent in vitro tests of stent prototypes showed satisfying properties concerning crimpability, expansion behavior and elastic recoil to demonstrate general feasibility. Further developments and additional testing will advance the implementation of a new treatment option of ETD.</jats:p>