| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Antonijević, Đorđe
University of Belgrade
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (6/6 displayed)
- 2024The intensity of subacute local biological effects after the implantation of ALBO-OS dental material based on hydroxyapatite and poly(lactide-co-glycolide): <i>in vivo</i> evaluation in rats
- 2023The influence of different radiopacifying agents on hermetical sealing ability of calcium silicate and calcium aluminate dental cements
- 2022Effect of various radiopacifiers on selected physical properties and cytotoxicity of calcium silicate based dental cement enriched with hydroxyapatite
- 2022Surface morphology, compressive strength and biocompatibility of calcium aluminate dental cement
- 2022Radiopacity of premixed and two-component Calcium silicate-based Root Canal sealerscitations
- 2021Biocompatibility Study of a New Dental Cement Based on Hydroxyapatite and Calcium Silicates: Focus on Liver, Kidney, and Spleen Tissue Effectscitations
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article
The intensity of subacute local biological effects after the implantation of ALBO-OS dental material based on hydroxyapatite and poly(lactide-co-glycolide): <i>in vivo</i> evaluation in rats
Abstract
<jats:title>Abstract</jats:title><jats:sec id="j_bmt-2023-0640_abs_001"><jats:title>Objectives</jats:title><jats:p>This study aimed to evaluate the intensity of the subacute local biological effects after implantation and osseoconductive potential of novel hydroxyapatite-based bone substitute coated with poly (lactide-co-glycolide), named ALBO-OS, in comparison to Bio-Oss<jats:sup>®</jats:sup>.</jats:p></jats:sec><jats:sec id="j_bmt-2023-0640_abs_002"><jats:title>Methods</jats:title><jats:p>Fifteen male Wistar rats, randomly assigned into groups: 10, 20, and 30 days (n꞊5), were subcutaneously implanted with ALBO-OS and Bio-Oss<jats:sup>®</jats:sup>. Furthermore, artificially made bone defects on both rat’s tibias were implanted with experimental materials. Unimplanted defects represented negative control. After the animals’ euthanizing, tissue samples were prepared and analyzed histologically and histomorphometrically.</jats:p></jats:sec><jats:sec id="j_bmt-2023-0640_abs_003"><jats:title>Results</jats:title><jats:p>Normal healing of the epithelial tissue was observed, with no signs of infection or necrosis. Minimal vascular congestion was noted immediately around the graft, with no signs of tissue oedema, with a minimal capsule thickness. The applied material did not cause an inflammatory response (IR) of significant intensity, and 20 days after implantation, the IR was mainly assessed as minimal. The tibial specimen showed that ALBO-OS has good osseoconductive potential, similar to Bio-Oss<jats:sup>®</jats:sup>, as well as low levels of acute and subacute inflammation.</jats:p></jats:sec><jats:sec id="j_bmt-2023-0640_abs_004"><jats:title>Conclusions</jats:title><jats:p>The tested material exhibits satisfying biocompatibility, similar to Bio-Oss<jats:sup>®</jats:sup>.</jats:p></jats:sec>