| People | Locations | Statistics |
|---|---|---|
| Naji, M. |
| |
| Motta, Antonella |
| |
| Aletan, Dirar |
| |
| Mohamed, Tarek |
| |
| Ertürk, Emre |
| |
| Taccardi, Nicola |
| |
| Kononenko, Denys |
| |
| Petrov, R. H. | Madrid |
|
| Alshaaer, Mazen | Brussels |
|
| Bih, L. |
| |
| Casati, R. |
| |
| Muller, Hermance |
| |
| Kočí, Jan | Prague |
|
| Šuljagić, Marija |
| |
| Kalteremidou, Kalliopi-Artemi | Brussels |
|
| Azam, Siraj |
| |
| Ospanova, Alyiya |
| |
| Blanpain, Bart |
| |
| Ali, M. A. |
| |
| Popa, V. |
| |
| Rančić, M. |
| |
| Ollier, Nadège |
| |
| Azevedo, Nuno Monteiro |
| |
| Landes, Michael |
| |
| Rignanese, Gian-Marco |
|
Oksman-Caldentey, Kirsi-Marja
VTT Technical Research Centre of Finland
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (7/7 displayed)
- 2007Effects of processing on availability of total plant sterols, steryl ferulates and steryl glycosides from wheat and rye brancitations
- 2007Improving oat Beta-glucan content by biotechnological methods
- 2005The action of berry phenolics against human intestinal pathogens
- 2004Metabolic engineering of plant cells using SOLUCEL technology
- 2004Novel tools for the engineering of secondary metabolite pathways in plants
- 2003A functional genomics approach to unravel plant secondary metabolism by combining transcriptional profiling with targeted metabolome analysis
- 2003Blanching and long-term freezing affect various bioactive compounds of vegetables in different wayscitations
Places of action
| Organizations | Location | People |
|---|
document
Metabolic engineering of plant cells using SOLUCEL technology
Abstract
SOLUCEL technology is based on the current advancement in understandingplant genomes, and on the development of novel tools for high throughputselecting and testing genes involved in the production of plant secondarymetabolites. It can be applied (i) to enhance the production of marketedhigh-value pharmaceuticals in plant cell cultures (ii) to develop reliable andreproducible sources of plant-derived molecules with potential pharmaceuticalvalue, and (iii) to increase the chemical diversity of plant based moleculesthrough Combinatorial Biochemistry. We have developed this technology usingthe nicotine alkaloid biosynthesis pathway as a model system. A few exampleswill be given of how overexpressing some novel genes can be used either totailor cell cultures to enhance the production of nicotine alkaloids or todirect biosynthetic pathways in related plant species. Furthermore, thesenovel genes may play an important role in secondary metabolism as masterregulators in general.