693.932 PEOPLE
| People | Locations | Statistics |
|---|---|---|
| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Fratzl, Prof. Dr. Dr. H. C. Peter
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (569/569 displayed)
- 2025A Bio‐Inspired Perspective on Materials Sustainabilitycitations
- 2025Material Composition Gradient Controls the Autonomous Opening of Banksia Seed Pods in Fire‐Prone Habitats
- 2024Growth of a Tessellation: Geometric rules for the Development of Stingray Skeletal Patterns
- 2024Solvent cavitation during ambient pressure drying of silica aerogelscitations
- 2024Postembedding Iodine Staining for Contrast‐Enhanced 3D Imaging of Bone Tissue Using Focused Ion Beam‐Scanning Electron Microscopy
- 2024Twisted-plywood-like tissue formation in vitro. Does curvature do the twist?citations
- 2023Calcitic Prisms of The Giant Seashell Pinna Nobilis Form Light Guide Arrayscitations
- 20233D osteocyte lacunar morphometry of human bone biopsies with high resolution microCT: from monoclonal gammopathy to newly diagnosed multiple myeloma
- 2023In Operando μCT Imaging of Silylated Silica Aerogels during Ambient Pressure Drying and Spring-Backcitations
- 2023Induced Mineralization of Hydroxyapatite in Escherichia coli Biofilms and the Potential Role of Bacterial Alkaline Phosphatasecitations
- 2023Bone Material Properties in Bone Diseases Affecting Childrencitations
- 2023Introduction: Sustainable Materialscitations
- 2023Logistics of Bone Mineralization in the Chick Embryo Studied by 3D Cryo FIB‐SEM Imagingcitations
- 2023Submicron‐Sized In Situ Osmotic Pressure Sensors for In Vitro Applications in Biologycitations
- 2023On shape forming by contractile filaments in the surface of growing tissuescitations
- 2022A 3D Network of Nanochannels for Possible Ion and Molecule Transit in Mineralizing Bone and Cartilagecitations
- 2022Mistletoe viscin: a hygro- and mechano-responsive cellulose-based adhesive for diverse material applicationscitations
- 2022Induced mineralization in Escherichia coli biofilms: the key role of bacterial alkaline phosphatase
- 2022Microenvironment-mediated cancer dormancy: Insights from metastability theorycitations
- 2022Special issue: bioinspired architectural and architected materialscitations
- 2022Spherulitic Crystal Growth Drives Mineral Deposition Patterns in Collagen‐Based Materialscitations
- 2022Mineralization generates megapascal contractile stresses in collagen fibrilscitations
- 2022Submicron-sized in-situ osmotic pressure sensors for in-vitro applications in biology
- 20213D Interrelationship between Osteocyte Network and Forming Mineral during Human Bone Remodelingcitations
- 2021Sequence-specific response of collagen-mimetic peptides to osmotic pressurecitations
- 2021Breast cancer–secreted factors perturb murine bone growth in regions prone to metastasiscitations
- 2021The Earth's Lithosphere Inspires Materials Designcitations
- 2021The spider cuticle: a remarkable material toolbox for functional diversitycitations
- 2021Architecturing materials at mesoscale: some current trendscitations
- 2021Wood and the activity of dead tissuecitations
- 2021Natural load-bearing protein materialscitations
- 2021Spatiotemporal Measurement of Osmotic Pressures by FRET Imagingcitations
- 2021Polyelectrolyte Substrate Coating for Controlling Biofilm Growth at Solid–Air Interfacecitations
- 2020Globular structure of the hypermineralized tissue in human femoral neckcitations
- 2020The mechanoresponse of bone is closely related to the osteocyte lacunocanalicular network architecturecitations
- 2020Heterogeneity of the osteocyte lacuno-canalicular network architecture and material characteristics across different tissue types in healing bonecitations
- 2020Damage tolerance of lamellar bonecitations
- 2020Network architecture strongly influences the fluid flow pattern through the lacunocanalicular network in human osteonscitations
- 2020Subcanalicular Nanochannel Volume Is Inversely Correlated With Calcium Content in Human Cortical Bonecitations
- 2020Human and mouse bones physiologically integrate in a humanized mouse model while maintaining species-specific ultrastructurecitations
- 2020Shape-preserving erosion controlled by the graded microarchitecture of shark tooth enameloidcitations
- 2018Biological composites—complex structures for functional diversitycitations
- 2018Correlative imaging reveals physiochemical heterogeneity of microcalcifications in human breast carcinomascitations
- 2018Reentrant phase transformation from crystalline ikaite to amorphous calcium carbonatecitations
- 2018PROTEIN-METAL COMPLEXES AS REVERSIBLE SACRIFICIAL BONDS IN THE SELF-HEALING MUSSEL BYSSAL THREADS
- 2018Quantitative shape analysis and mechanics of intertesseral joints in tessellated cartilage of sharks and rays
- 2018MATERIALS SCIENCE Wood made denser and stronger
- 2018Metal-Tunable Self-Assembly of Hierarchical Structure in Mussel-Inspired Peptide Filmscitations
- 2018The three-dimensional arrangement of the mineralized collagen fibers in elephant ivory and its relation to mechanical and optical propertiescitations
- 2018Correlations between nanostructure and micromechanical properties of healing bonecitations
- 2018Climate-Dependent Heat-Triggered Opening Mechanism of Banksia Seed Podscitations
- 2018A new twist on sea silk: the peculiar protein ultrastructure of fan shell and pearl oyster byssuscitations
- 2018Temperature-induced self-sealing capability of Banksia folliclescitations
- 2018Hydrogen Bonding in Amorphous Calcium Carbonate and Molecular Reorientation Induced by Dehydrationcitations
- 2018Preface to the proceedings of the 12th international conference on the chemistry and biology of mineralized tissues
- 2018Tensile forces drive a reversible fibroblast-to-myofibroblast transition during tissue growth in engineered cleftscitations
- 2018The Crystallization of Amorphous Calcium Carbonate is Kinetically Governed by Ion Impurities and Water.citations
- 2018Additives influence the phase behavior of calcium carbonate solution by a cooperative ion-association processcitations
- 2018Interplay between Calcite, Amorphous Calcium Carbonate, and Intracrystalline Organics in Sea Urchin Skeletal Elementscitations
- 2017Combined Experimental and Theoretical Approach to the Kinetics of Magnetite Crystal Growth from Primary Particles
- 2017Combining Coherent Hard X-Ray Tomographies with Phase Retrieval to Generate Three-Dimensional Models of Forming Bonecitations
- 2017Nano-channels in the spider fang for the transport of Zn ions to cross-link His-rich proteins pre-deposited in the cuticle matrixcitations
- 2017Control of Polymorph Selection in Amorphous Calcium Carbonate Crystallization by Poly(Aspartic Acid): Two Different Mechanismscitations
- 2017Nano-scale modulus mapping of biological composite materials: Theory and practicecitations
- 2017Crack driving force in twisted plywood structurescitations
- 2017Mechanical behavior of idealized, stingray-skeleton-inspired tiled composites as a function of geometry and material propertiescitations
- 2017Ultrasound-driven titanium modification with formation of titania based nanofoam surfacescitations
- 2017The small world of osteocytes: connectomics of the lacuno-canalicular network in bonecitations
- 2017The Role of Titanium Surface Nanostructuring on Preosteoblast Morphology, Adhesion, and Migrationcitations
- 2017Pyridinoline collagen cross-link content at actively forming trabecular surfaces is associated with fragility fracture incidence independent of BMD and the clinical diagnosis.
- 2017On the Phase Diagram of Calcium Carbonate Solutionscitations
- 2017IFITM5 (BRIL) p.S40L mutation causing atypical type VI OI results in unique bone material phenotype impacting both endochondral ossification and chondrocyte development.
- 2017Dendritic polyglycerol anions for the selective targeting of native and inflamed articular cartilagecitations
- 2017Multiscale Analysis of Mineralized Collagen Combining X-ray Scattering and Fluorescence with Raman Spectroscopy under Controlled Mechanical, Thermal, and Humidity Environmentscitations
- 2017Ultrastructural, material and crystallographic description of endophytic masses - A possible damage response in shark and ray tessellated calcified cartilagecitations
- 2017Calcified cartilage or bone? Collagens in the tessellated endoskeletons of cartilaginous fish (sharks and rays)citations
- 2017Unraveling the Molecular Requirements for Macroscopic Silk Supercontractioncitations
- 2017Pattern formation and collective effects in populations of magnetic microswimmerscitations
- 2017Scaffold curvature-mediated novel biomineralization process originates a continuous soft tissue-to-bone interfacecitations
- 2017Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasiscitations
- 2017Fkbp10 Deletion in Osteoblasts Leads to Qualitative Defects in Bonecitations
- 2017Impregnation and Swelling of Wood with Salts: Ion Specific Kinetics and Thermodynamics Effectscitations
- 2017Relation between the Macroscopic Pattern of Elephant Ivory and Its Three-Dimensional Micro-Tubular Networkcitations
- 2016Aging Versus Postmenopausal Osteoporosis: Bone Composition and Maturation Kinetics at Actively-Forming Trabecular Surfaces of Female Subjects Aged 1 to 84 Yearscitations
- 2016Honeycomb Actuators Inspired by the Unfolding of Ice Plant Seed Capsulescitations
- 2016Ultrastructural and developmental features of the tessellated endoskeleton of elasmobranchs (sharks and rays)citations
- 2016The mechanics of tessellations - bioinspired strategies for fracture resistancecitations
- 2016The nanostructure of murine alveolar bone and its changes due to type 2 diabetescitations
- 2016Function by internal structure-preface to the special issue on bioinspired hierarchical materialscitations
- 2016Ultrasonically Produced Porous Sponge Layer on Titanium to Guide Cell Behaviorcitations
- 2016Light-Induced Water Splitting Causes High-Amplitude Oscillation of pH-Sensitive Layer-by-Layer Assemblies on TiO2citations
- 2016Mineral Formation in the Larval Zebrafish Tail Bone Occurs via an Acidic Disordered Calcium Phosphate Phasecitations
- 2016Gas barrier properties of bio-inspired Laponite–LC polymer hybrid filmscitations
- 2016Cooperative behavior of a sacrificial bond network and elastic framework in providing self-healing capacity in mussel byssal threadscitations
- 2016Macromolecular recognition directs calcium ions to coccolith mineralization sites
- 2016Ordering of protein and water molecules at their interfaces with chitin nano-crystalscitations
- 2016Inherent Role of Water in Damage Tolerance of the Prismatic Mineral–Organic Biocomposite in the Shell of Pinna Nobiliscitations
- 2016The role of water on the structure and mechanical properties of a thermoplastic natural block co-polymer from squid sucker ring teethcitations
- 2016A new treatment of transient grain growthcitations
- 2016Gradual conversion of cellular stress patterns into pre-stressed matrix architecture during in vitro tissue growthcitations
- 2016To build a shark-3D tiling laws of tessellated cartilage
- 2016Switching the Stiffness of Polyelectrolyte Assembly by Light to Control Behavior of Supported Cellscitations
- 2016Chemical, colloidal and mechanical contributions to the state of water in wood cell wallscitations
- 2016A materials science vision of extracellular matrix mineralizationcitations
- 2016Evidence for a Role for Nanoporosity and Pyridinoline Content in Human Mild Osteogenesis Imperfectacitations
- 2016Water-Mediated Collagen and Mineral Nanoparticle Interactions Guide Functional Deformation of Human Tooth Dentincitations
- 2016Solving conflicting functional requirements by hierarchical structuring-Examples from biological materialscitations
- 2016Bone mineralization pathways during the rapid growth of embryonic chicken long bonescitations
- 2015Gains and losses of coral skeletal porosity changes with ocean acidification acclimationcitations
- 2015On the pathway of mineral deposition in larval zebrafish caudal fin bonecitations
- 2015Effect of in vivo loading on bone composition varies with animal agecitations
- 2015Opposite Particle Size Effect on Amorphous Calcium Carbonate Crystallization in Water and during Heating in Aircitations
- 2015BMP delivery complements the guiding effect of scaffold architecture without altering bone microstructure in critical-sized long bone defects: A multiscale analysiscitations
- 2015Micro- and nano-structural details of a spider's filter for substrate vibrationscitations
- 2015Osmotically driven tensile stress in collagen-based mineralized tissuescitations
- 2015Compressive Residual Strains in Mineral Nanoparticles as a Possible Origin of Enhanced Crack Resistance in Human Tooth Dentincitations
- 2015High resolution 3D laboratory x-ray tomography data of femora from young, 1-14 day old C57BL/6 micecitations
- 2015Recombinant engineering of reversible cross-links into a resilient biopolymercitations
- 2015The Mechanism of Color Change in the Neon Tetra Fish: a Light-Induced Tunable Photonic Crystal Arraycitations
- 20153D Tissue Growth in vivo under Geometrical Constraints
- 2015Characterizing moisture-dependent mechanical properties of organic materialscitations
- 2015Layered growth of crayfish gastrolith: About the stability of amorphous calcium carbonate and role of additivescitations
- 2015Unique micro- and nano-scale mineralization pattern of human osteogenesis imperfecta type VI bonecitations
- 2015Elastic response of mesoporous silicon to capillary pressures in the porescitations
- 2015Availability of extracellular matrix biopolymers and differentiation state of human mesenchymal stem cells determine tissue-like growth in vitrocitations
- 2015Fast Magnetic Micropropellers with Random Shapescitations
- 2015The use of ultrasonic cavitation for near-surface structuring of robust and low-cost AlNi catalysts for hydrogen productioncitations
- 2015Electron microscope analyses of the bio-silica basal spicule from the Monorhaphis chuni spongecitations
- 2015Osmotic pressure induced tensile forces in tendon collagencitations
- 2015Eshelby Twist as a Possible Source of Lattice Rotation in a Perfectly Ordered Protein/Silica Structure Grown by a Simple Organismcitations
- 2015Tissue growth controlled by geometric boundary conditions: a simple model recapitulating aspects of callus formation and bone healingcitations
- 2015Making a tooth mimic
- 2015Multi-scale thermal stability of a hard thermoplastic protein-based material
- 2015Registering 2D and 3D imaging data of bone during healingcitations
- 2015Long bone maturation is driven by pore closing: A quantitative tomography investigation of structural formation in young C57BL/6 micecitations
- 2015Fragility of Bone Material Controlled by Internal Interfacescitations
- 2015Energy dissipation and recovery in a simple model with reversible cross-linkscitations
- 2015The Geometric Design and Fabrication of Actuating Cellular Structures
- 2015From Beetles in Nature to the Laboratory: Actuating Underwater Locomotion on Hydrophobic Surfacescitations
- 2015Extra dimension for bone analysis
- 2014Mapping dynamical mechanical properties of osteonal bone by scanning acoustic microscopy in time-of-flight modecitations
- 2014Rapid alterations of avian medullary bone material during the daily egg-laying cyclecitations
- 2014A spider's biological vibration filtercitations
- 2014The Mechanical Role of Metal Ions in Biogenic Protein-Based Materialscitations
- 2014Mechanical and structural properties of bone in non-critical and critical healing in ratcitations
- 2014Nanoscale elastic modulus mapping revisited: The concept of effective masscitations
- 2014APPLIED PHYSICS The virtues of tiling
- 2014Early diagenesis of elephant tusk in marine environmentcitations
- 2014Relationship between nanoscale mineral properties and calcein labeling in mineralizing bone surfacescitations
- 2014Pressurized honeycombs as soft-actuators: a theoretical studycitations
- 2014Nanocrystalline Calcitic Lens Arrays Fabricated by Self-Assembly Followed by Amorphous-to-Crystalline Phase Transformationcitations
- 2014A Perfectly Periodic Three-Dimensional Protein/Silica Mesoporous Structure Produced by an Organismcitations
- 2014A customizable software for fast reduction and analysis of large X-ray scattering data sets: applications of the new DPDAK package to small-angle X-ray scattering and grazing-incidence small-angle X-ray scatteringcitations
- 2014Neurofibromin inactivation impairs osteocyte development in Nf1Prx1 and Nf1Col1 mouse modelscitations
- 2014Pediatric reference Raman data for material characteristics of iliac trabecular bonecitations
- 2014Hierarchically Structured Vanadium Pentoxide-Polymer Hybrid Materialscitations
- 2014Multiscale structural gradients enhance the biomechanical functionality of the spider fangcitations
- 2014Increased bone remodelling around titanium implants coated with chondroitin sulfate in ovariectomized ratscitations
- 2014Particle Accretion Mechanism Underlies Biological Crystal Growth from an Amorphous Precursor Phasecitations
- 2014Hydro-actuation of ice plant seed capsules powered by water uptakecitations
- 2014Composition and Mechanical Properties of a Protein/Silica Hybrid Material Forming the Micron-Thick Axial Filament in the Spicules of Marine Spongescitations
- 2014Enhancing soft matter mechanics via metal coordination: lessons from the mussel byssus
- 2014Magnetic force imaging of a chain of biogenic magnetite and Monte Carlo analysis of tip-particle interactioncitations
- 2014Relationship of Bone Mineralization Density Distribution (BMDD) in Cortical and Cancellous Bone Within the Iliac Crest of Healthy Premenopausal Womencitations
- 2014Mesoporous silica: a perfectly periodic three-dimensional protein/silica mesoporous structure produced by an organism (adv. Mater. 11/2014).citations
- 2014Nanostructure of Biogenic Calcite and Its Modification under Annealing: Study by High-Resolution X-ray Diffraction and Nanoindentationcitations
- 2014Pressurized honeycombs as soft-actuators: a theoretical study (vol 11, 20140458, 2014)citations
- 2014Multiscale, Converging Defects of Macro-Porosity, Microstructure and Matrix Mineralization Impact Long Bone Fragility in NF1citations
- 2014Self-similar mesostructure evolution of the growing mollusc shell reminiscent of thermodynamically driven grain growthcitations
- 2014Selectivity in Bone Targeting with Multivalent Dendritic Polyanion Dye Conjugatescitations
- 2014Measuring the distribution of cellulose microfibril angles in primary cell walls by small angle X-ray scatteringcitations
- 2014Magnetite Crystal Orientation in Magnetosome Chainscitations
- 2014Improvements of strength and fracture resistance by spatial material property variationscitations
- 2014Changes in the Degree of Mineralization with Osteoporosis and its Treatmentcitations
- 2014Relationship between the v(2)PO(4)/amide III ratio assessed by Raman spectroscopy and the calcium content measured by quantitative backscattered electron microscopy in healthy human osteonal bonecitations
- 2014The role of topology and thermal backbone fluctuations on sacrificial bond efficacy in mechanical metalloproteinscitations
- 2014Simultaneous Raman Microspectroscopy and Fluorescence Imaging of Bone Mineralization in Living Zebrafish Larvaecitations
- 2014Mineral particle size in children with osteogenesis imperfecta type I is not increased independently of specific collagen mutationscitations
- 2014Influence of sacrificial bonds on the mechanical behaviour of polymer chainscitations
- 2014The role of angular reflection in assessing elastic properties of bone by scanning acoustic microscopycitations
- 2013Preface for the special issue celebrating Stephen Weiner's 65th birthdaycitations
- 2013Tissue growth into three-dimensional composite scaffolds with controlled micro-features and nanotopographical surfacescitations
- 2013Calcite crystal growth by a solid-state transformation of stabilized amorphous calcium carbonate nanospheres in a hydrogelcitations
- 2013Selecting for function: Solution synthesis of magnetic nanopropellerscitations
- 2013Nano- to Macroscale Remodeling of Functional Tissue-Engineered Bonecitations
- 2013Apatite alignment and orientation at the Angstrom and nanometer length scales shed light on the adaptation of dentine to whole tooth mechanical functioncitations
- 2013Osteoclasts on bone and dentin in vitro: Mechanism of trail formation and comparison of resorption behaviorcitations
- 2013Modelling the role of surface stress on the kinetics of tissue growth in confined geometriescitations
- 2013In situ elastic modulus measurements of ultrathin protein-rich organic layers in biosilica: Towards deeper understanding of superior resistance to fracture of biocompositescitations
- 2013Physicochemical basis for water-actuated movement and stress generation in nonliving plant tissuescitations
- 2013Polarized Raman Anisotropic Response of Collagen in Tendon: Towards 3D Orientation Mapping of Collagen in Tissuescitations
- 2013Nucleation and growth of magnetite from solutioncitations
- 2013Bone Scaffold Covers All Angles
- 2013Hierarchical structuring of liquid crystal polymer-laponite hybrid materialscitations
- 2013Geometry as a Factor for Tissue Growth: Towards Shape Optimization of Tissue Engineering Scaffoldscitations
- 2013Structural and mechanical properties of the arthropod cuticlecitations
- 2013Characterizing the transformation near indents and cracks in clinically used dental yttria-stabilized zirconium oxide constructscitations
- 2013Architecture of the osteocyte network correlates with bone material qualitycitations
- 2013Guanine-based photonic crystals in fish scales form from an amorphous precursorcitations
- 2013New materials through bioinspiration and nanosciencecitations
- 2013Multilevel architectures in natural materialscitations
- 2013Enhanced cellulose orientation analysis in complex model plant tissuescitations
- 2013Materials Design Inspired by Nature, Function through Inner Architecture
- 2013Intrafibrillar plasticity through mineral/collagen sliding is the dominant mechanism for the extreme toughness of antler bonecitations
- 2013Self-repair of a biological fiber guided by an ordered elastic frameworkcitations
- 2013Imaging the nanostructure of bone and dentin through small- and wide-angle X-ray scatteringcitations
- 2013Materials Design Inspired by Nature Function Through Inner Architecture Preface
- 2013Quantifying degradation of collagen in ancient manuscripts: The case of the Dead Sea Temple Scrollcitations
- 2013All but diamonds-Biological materials are not forevercitations
- 2013Thermodynamic modeling of a phase transformation in protein filaments with mechanical functioncitations
- 2013Nanoengineered colloidal probes for raman-based detection of biomolecules inside living cellscitations
- 2012Self-assembly of amorphous calcium carbonate microlens arrayscitations
- 2012Porous scaffold architecture guides tissue formationcitations
- 2012Evidence of polyphosphates and their distribution in active biological apatite mineralization sites of stingray jawscitations
- 2012Microcracks and Osteoclast Resorption Activity In Vitrocitations
- 2012Enhancing low cost stainless steel implants: Bioactive silica-based sol-gel coatings with wollastonite particlescitations
- 2012Hierarchy in Natural Materials
- 2012Osteoclasts on bone and dentin in vitro: Mechanism of degradation and comparison of resorption behaviourcitations
- 2012Finite Element Modeling of the Cyclic Wetting Mechanism in the Active Part of Wheat Awnscitations
- 2012Bone Material Properties in Premenopausal Women With Idiopathic Osteoporosiscitations
- 2012Functional mapping of bone on the micrometer-scale by scanning acoustic microscopycitations
- 2012Polymer Science: A Comprehensive Reference
- 2012Hierarchical Calcite Crystals with Occlusions of a Simple Polyelectrolyte Mimic Complex Biomineral Structurescitations
- 2012A Composite Matter of Alignmentcitations
- 2012Semi-analytical approaches to assess the crack driving force in periodically heterogeneous elastic materialscitations
- 2012Enamel-like apatite crown covering amorphous mineral in a crayfish mandiblecitations
- 2012Bone matrix mineralization in osteogenesis imperfecta type VI
- 2012Pseudoelastic behaviour of a natural material is achieved via reversible changes in protein backbone conformationcitations
- 2012SMAD versus Non-SMAD Signaling Is Determined by Lateral Mobility of Bone Morphogenetic Protein (BMP) Receptorscitations
- 2012Mineral particle size in children with dominant osteogenesis imperfecta is not associated with specific collagen mutation: A synchrotron X-ray scattering studycitations
- 2012Analysis of bone material during osteotomy healing in rats
- 2012Tilted cellulose arrangement as a novel mechanism for hygroscopic coiling in the stork's bill awncitations
- 2012X-ray vector radiography for bone micro-architecture diagnosticscitations
- 2012Bone tissue engineering: From bench to bedsidecitations
- 2012Collagencitations
- 2012How Linear Tension Converts to Curvature: Geometric Control of Bone Tissue Growthcitations
- 2012Plant Cystoliths: A Complex Functional Biocomposite of Four Distinct Silica and Amorphous Calcium Carbonate Phasescitations
- 2012Synchrotron 3D SAXS analysis of bone nanostructurecitations
- 2012Keynote: Multi-mode imaging of bone and fracture callus
- 2012A Spider's Fang: How to Design an Injection Needle Using Chitin-Based Composite Materialcitations
- 2012Accelerated Growth Plate Mineralization and Foreshortened Proximal Limb Bones in Fetuin-A Knockout Micecitations
- 2011THE ROLE OF OSTEOCYTES IN THE SKELETAL PATHOLOGY OF NEUROFIBROMATOSIS TYPE I (NF1)
- 2011Spatial-temporal mapping of bone structural and elastic properties in a sheep model following osteotomycitations
- 2011Artful interfaces within biological materialscitations
- 2011Structural purity of magnetite nanoparticles in magnetotactic bacteriacitations
- 2011Nanostructure of Biogenic Calcite Crystals: A View by Small-Angle X-Ray Scatteringcitations
- 2011The mechanical heterogeneity of the hard callus influences local tissue strains during bone healing: A finite element study based on sheep experimentscitations
- 2011Lathyrism-induced alterations in collagen cross-links influence the mechanical properties of bone material without affecting the mineralcitations
- 2011Origami-like unfolding of hydro-actuated ice plant seed capsulescitations
- 2011Hierarchy in Natural Materialscitations
- 2011Fetal and postnatal mouse bone tissue contains more calcium than is present in hydroxyapatitecitations
- 2011Trabecular bone remodelling simulated by a stochastic exchange of discrete bone packets from the surfacecitations
- 2011Three-dimensional tissue growth in polymer scaffolds with different stiffness and in-vitro influence of BMP-2 on tissue formation in hydroxyapatite scaffolds
- 2011Identification of root filling interfaces by microscopy and tomography methodscitations
- 2011Bioinspired Design Criteria for Damage-Resistant Materials with Periodically Varying Microstructurecitations
- 2011Cooperation of length scales and orientations in the deformation of bovine bonecitations
- 2011Effect of phosphorylation on the interaction of calcium with leucine-rich amelogenin peptidecitations
- 2011Poorly Ordered Bone as an Endogenous Scaffold for the Deposition of Highly Oriented Lamellar Tissue in Rapidly Growing Ovine Bonecitations
- 2011The physics of tissue patterning and extracellular matrix organisation: How cells join forcescitations
- 2011An Alternative Route Towards Metal-Polymer Hybrid Materials Prepared by Vapor-Phase Processingcitations
- 2011Tubular frameworks guiding orderly bone formation in the antler of the red deer (Cervus elaphus)citations
- 2011Microcracks and osteoclast resorption activity in vitro
- 2011An excursion into the design space of biomimetic architectured biphasic actuatorscitations
- 2011Geometric control of three-dimensional tissue growth
- 2011In situ observation of cluster formation during nanoparticle solution casting on a colloidal filmcitations
- 2011Observations of Multiscale, Stress-Induced Changes of Collagen Orientation in Tendon by Polarized Raman Spectroscopycitations
- 2011Structural Adaptation of Trabecular Bone Revealed by Position Resolved Analysis of Proximal Femora of Different Primatescitations
- 2011Mechanical adaptation of biological materials - The examples of bone and woodcitations
- 2011Mapping Lattice Spacing and Composition in Biological Materials by Means of Microbeam X-Ray Diffractioncitations
- 2011The Heterogeneous Mineral Content of Bone-Using Stochastic Arguments and Simulations to Overcome Experimental Limitationscitations
- 2011The interplay between calcium homeostasis and bone mineralization - A computational approach
- 2011Mapping nanomeehanical properties near internal interfaces in biological materialscitations
- 2011The organization of the osteocyte network mirrors the extracellular matrix orientation in bonecitations
- 2011The effect of a disturbed mineralization process on the bone mineralization density distribution (BMDD)
- 2010Influences of age and mechanical stability on volume, microstructure, and mineralization of the fracture callus during bone healing: Is osteoclast activity the key to age-related impaired healing?citations
- 2010Self-assembled collagen-apatite matrix with bone-like hierarchycitations
- 2010Moisture changes in the plant cell wall force cellulose crystallites to deformcitations
- 2010Elucidating the mechanical principles of stem movements in heliotropism
- 2010Designing biomimetic scaffolds for bone regeneration: Why aim for a copy of mature tissue properties if nature uses a different approach?citations
- 2010Biomimetic Principles in Polymer and Material Sciencecitations
- 2010Collagen orientation during early stages of bone fracture healing investigated by polarized Raman imagingcitations
- 2010Improving the osteointegration and bone-implant interface by incorporation of bioactive particles in sol-gel coatings of stainless steel implantscitations
- 2010In-situ Raman Spectroscopic Imaging of a Mussel Coating and Adhesive
- 2010G-fibres in storage roots of Trifolium pratense (Fabaceae): Tensile stress generators for contractioncitations
- 2010Iron-clad fibers: A metal-based biological strategy for hard flexible coatingscitations
- 2010Biological compositescitations
- 2010Scanning small-angle X-ray scattering analysis of the size and organization of the mineral nanoparticles in fluorotic bone using a stack of cards modelcitations
- 2010Bio-Inspired Materials - Mining the Old Literature for New Ideascitations
- 2010In-situ Damage Assessment of Collagen within Ancient Manuscripts Written on Parchment: A Polarized Raman Spectroscopy Approach
- 20103D variations in human crown dentin tubule orientation: A phase-contrast microtomography studycitations
- 2010Mechanisms of Bone Deformation and Fracturecitations
- 2010A kinetic model of the transformation of a micropatterned amorphous precursor into a porous single crystalcitations
- 2010Temporal tissue patterns in bone healing of sheep.citations
- 2010Mineralization density distribution of postmenopausal osteoporotic bone is restored to normal after long-term alendronate treatment: qBEI and sSAXS data from the fracture intervention trial long-term extension (FLEX)citations
- 2010Size and habit of mineral particles in bone and mineralized callus during bone healing in sheepcitations
- 2010A theoretical model for tissue growth in confined geometriescitations
- 2010Pore-lattice deformations in ordered mesoporous matrices: Experimental studies and theoretical analysiscitations
- 2010Sonication-assisted synthesis of large, high-quality mercury thiolate single crystals directly from liquid mercurycitations
- 2010Effect of minimal defects in periodic cellular solidscitations
- 2010On the mineral in collagen of human crown dentinecitations
- 2010Plant Movement Mechanisms - Cell Wall Architectures Enable Actuation without Muscles
- 2010Geometric Control of Tissue Growthcitations
- 2010Mineral crystal alignment in mineralized fracture callus determined by 3D small-angle X-ray scatteringcitations
- 2010Biomimetics and Biotemplating of Natural Materialscitations
- 2010Two stages in three-dimensional in vitro growth of tissue generated by osteoblastlike cellscitations
- 2010Role of amelogenin self-assembly in protein-mediated dental enamel formationcitations
- 2010Mapping amorphous calcium phosphate transformation into crystalline mineral from the cell to the bone in zebrafish fin rayscitations
- 2010Cellulose microfibril orientation of Picea abies and its variability at the micron-level determined by Raman imagingcitations
- 2010Strontium is incorporated into mineral crystals only in newly formed bone during strontium ranelate treatmentcitations
- 2010Cortical bone composition and orientation as a function of animal and tissue age in mice by Raman spectroscopycitations
- 2010Unifying design strategies in demosponge and hexactinellid skeletal systemscitations
- 2010Amelogenin Nanoparticles in Suspension: Deviations from Spherical Shape and pH-Dependent Aggregationcitations
- 2010Bone material quality in transiliac bone biopsies of postmenopausal osteoporotic women after 3 years of strontium ranelate treatmentcitations
- 2010Surfactant self-assembly in cylindrical silica nanoporescitations
- 2010In vitro bioactivity of bioresorbable porous polymeric scaffolds incorporating hydroxyapatite microspherescitations
- 2009Cortical bone orientation and composition in a mouse model as a function of tissue age vs animal agecitations
- 2009Vibrational spectroscopy in biomedical science: Bonecitations
- 2009Nanoscale deformation mechanisms in bonecitations
- 2009New suggestions for the mechanical control of bone remodelingcitations
- 2009Mineral deposition and growth during embryonal bone development in mice
- 2009The grinding tip of the sea urchin tooth exhibits exquisite control over calcite crystal orientation and Mg distributioncitations
- 2009Relationship of osteoclast resorption activity and bone surface roughnesscitations
- 2009Combination of nanoindentation and quantitative backscattered electron imaging revealed altered bone material properties associated with femoral neck fragilitycitations
- 2009The trabecular bone architecture in proximal femora of primates with different locomotor preferences indicates different adaptation mechanismscitations
- 2009Sacrificial ionic bonds need to be randomly distributed to provide shear deformabilitycitations
- 2009Biomaterial systems for mechanosensing and actuationcitations
- 2009Digital image correlation shows localized deformation bands in inelastic loading of fibrolamellar bonecitations
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- 2009Plants control the properties and actuation of their organs through the orientation of cellulose fibrils in their cell wallscitations
- 2009Biological and biomimetic materialscitations
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- 2009Collagen insulated from tensile damage by domains that unfold reversibly: In situ X-ray investigation of mechanical yield and damage repair in the mussel byssuscitations
- 2008Characterisation of bone mineral density around modified titanium implants in an osteoporotic rat model with synchrotron microcomputed tomography
- 2008The implication of chemical extraction treatments on the cell wall nanostructure of softwoodcitations
- 2008Microstructure of cortical bone as studied by Raman spectroscopy (composition vs orientation)
- 2008Three-dimensional geometry determines the tissue formation kinetics in vitro
- 2008Stress generation in the tension wood of poplar is based on the lateral swelling power of the G-layercitations
- 2008Complex transitions in the Bone Mineralization Density Distribution (BMDD) caused by changes in bone turnover
- 2008Characteristics of mineral particles in the callus during fracture healing in a sheep model
- 2008Collagen's contribution to bone strength
- 2008Towards understanding of trabecular bone failure by deformation localisation
- 2008Mechanics of the Wood Cell Wallcitations
- 2008Cellulose fibrils direct plant organ movementscitations
- 2008Collagen: Structure and mechanics, an introductioncitations
- 2008Tough lessons from bone: Extreme mechanical anisotropy at the mesoscalecitations
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- 2008Identifying typical patterns of bone healing to understanding endogenous tissue formation
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- 2008Tibia and humerus bowing in a mouse model for neurofibromatosis type 1
- 2008Osteoporosis: More than bone turnover?
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- 2007Hierarchical assembly of the siliceous skeletal lattice of the hexactinellid sponge Euplectella aspergillumcitations
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- 2007Impact of a three-dimensional hydroxylapatite scaffold on differentiation of osteoblasts and tissue formation in vitro
- 2007Fracture of poly(vinylidene fluoride): A combined synchrotron and laboratory in-situ X-ray scattering studycitations
- 2007Tensile and compressive stresses in tracheids are induced by swelling based on geometrical constraints of the wood cellcitations
- 2007Raman imaging of two orthogonal planes within cortical bonecitations
- 2007Three-dimensional growth behavior of osteoblasts on biomimetic hydroxylapatite scaffoldscitations
- 2007Hindered crack propagation in materials with periodically varying young's modulus - Lessons from biological materialscitations
- 2007Biomimetic materials research: What can we really learn from nature's structural materials?citations
- 2007A new experimental station for simultaneous X-ray microbeam scanning for small- and wide-angle scattering and fluorescence at BESSY IIcitations
- 2007Evidence for an elementary process in bone plasticity with an activation enthalpy of 1 eVcitations
- 2007Scanning texture analysis of lamellar bone using microbeam synchrotron X-ray radiationcitations
- 2007Osteonecrosis of the jaw under biphosphonate therapy - A German register for patients with osteonecrosis of the jaw
- 2007Evidence that treatment with risedronate in women with postmenopausal osteoporosis affects bone mineralization and bone volumecitations
- 2007Hierarchical Structure and Repair of Bone: Deformation, Remodelling, Healingcitations
- 2007Mineralization status of bone matrix in postmenopausal women during a 10-year alendronate treatment period
- 2007Scanning X-ray imaging with small-angle scattering contrastcitations
- 2007The relation between mechanical stimulus and cell response in trabecular bone remodeling
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- 2007Nature's hierarchical materialscitations
- 2007The bone mineralization density distribution as a fingerprint of the mineralization processcitations
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- 2007The role of wheat awns in the seed dispersal unitcitations
- 2007Osteonecrosis of jaw under bisphosphonate therapy: Patient profile and risk assessment
- 2007Scaffold geometry regulates tissue growth in vitro
- 2007Bone quality in mild primary hyperparathyroidism
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- 2007Bone material characteristics in osteoporotic postmenopausal women after 3-year treatment with strontium ranelate
- 2007Reversible switching of hydrogel-actuated nanostructures into complex micropatternscitations
- 2006Pamidronate does not adversely affect bone intrinsic material properties in children with osteogenesis imperfectacitations
- 2006Diffusion and creep in multi-component alloys with non-ideal sources and sinks for vacanciescitations
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- 2006Small-angle scattering from spherical particles on randomly oriented interfaces
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- 2006Complementary information on in vitro conversion of amorphous (precursor) calcium phosphate to hydroxyapatite from raman microspectroscopy and wide-angle X-ray scatteringcitations
- 2006Mechanical modulation at the lamellar level in osteonal bonecitations
- 2006Fresnel-propagated imaging for the study of human tooth dentin by partially coherent x-ray tomographycitations
- 2006Raman spectral mapping of bone osteonal tissues
- 2006Three-year strontium ranelate treatment in osteoporotic women preserves collagen quality in newly formed bone
- 2006Lead accumulation in tidemark of articular cartilagecitations
- 2006Bone osteonal tissues by Raman spectral mapping: Orientation-compositioncitations
- 2006Small-angle X-ray scattering to characterize nanostructures in inorganic and hybrid materials chemistrycitations
- 2006Fibrillar level fracture in bone beyond the yield pointcitations
- 2006Micromechanical properties of biological silica in skeletons of deep-sea spongescitations
- 2006Small-angle scattering of S-layer metallizationcitations
- 2006Detection of lead accumulation in tidemarks of articular cartilage
- 2006Effects of 3- and 5-year treatment with risedronate on bone mineralization density distribution in triple biopsies of the iliac crest in postmenopausal women (vol 21, pg 1106, 2006)
- 2006Individual bone structural unit characteristics in osteoporotic postmenopausal women after 3-year treatment with strontium ranelate
- 2006Relationship between trabecular and cortical bone mineralization density distribution (BMDD) in iliac crest biopsies from healthy individuals and cases of primary hyperparathyroidism
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- 2006Materials science basis of bone quality
- 2006Measurements of mineralization density profiles in bone formation sites reveals a biphasic mineralization process of bone matrix
- 2006Modeling the bone mineralization density distribution and its time evolution
- 2006Effects of 3- and 5-year treatment with risedronate on bone mineralization density distribution in triple biopsies of the iliac crest in postmenopausal womencitations
- 2006Cooperative deformation of mineral and collagen in bone at the nanoscalecitations
- 2006Erratum: Effects of 3- and 5-year treatment with risedronate on bone mineralization density distribution in triple biopsies of the iliac crest in postmenopausal women (Journal of Bone and Mineral Research (July 2006) 21, (1106-1112))
- 2006From brittle to ductile fracture of bonecitations
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- 2005Effects of 3-and 5-year treatment with risedronate on the bone mineral maturity/crystallinity and collagen cross-links as a function of trabecular surface activity
- 2005Correlation of nanomechanical properties and bone organic/inorganic components in osteolathyritic treated rat bones
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- 2005Reduced mineralization density of bone in premenopausal women with idiopathic osteoporosis
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- 2005Combined treatment with PTH (1-34) and OPG increases bone volume and uniformity of mineralization in aged ovariectomized ratscitations
- 2005The contribution of microarchitecture and bone mineralization density distribution (BMDD) to fracture risk
- 2005Relating local bone stiffness and calcium content by combined nanoindentation and backscattered electron imaging
- 2004Application of the thermodynamic extremal principle to the diffusional phase transformationscitations
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- 2004Cellular Solids beyond the Apparent Density - An Experimental Assessment of Mechanical Propertiescitations
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- 2003Targeted overexpression of vitamin D receptor in osteoblasts increases calcium concentration without affecting structural properties of bone mineral crystalscitations
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- 2003Long-term correlations distinguish coarsening mechanisms in alloys
- 2003Bone quality at material level as defined by concentration, size, shape, and alignment of mineral particles
- 2003Cyclical pamidronate treatment does not affect bone mineralization density distribution in children suffering from osteogenesis imperfecta
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- 2003RAPID PROTOTYPING - A ROUTE FOR THE FABRICATION OF BIOMIMETIC CELLULAR MATERIALS
- 2003By which mechanism does coarsening in phase-separating alloys proceed?citations
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- 2003Increased uniformity in bone mineralization after combined treatment of PTH-(1-34) and OPG in osteopenic ovariectomized rats
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Multiscale, Converging Defects of Macro-Porosity, Microstructure and Matrix Mineralization Impact Long Bone Fragility in NF1
Abstract
Bone fragility due to osteopenia, osteoporosis or debilitating focal skeletal dysplasias is a frequent observation in the Mendelian disease Neurofibromatosis type 1 (NF1). To determine the mechanisms underlying bone fragility in NF1 we analyzed two conditional mouse models, Nf1Prx1 (limb knock-out) and Nf1Col1 (osteoblast specific knock-out), as well as cortical bone samples from individuals with NF1. We examined mouse bone tissue with micro-computed tomography, qualitative and quantitative histology, mechanical tensile analysis, small-angle X-ray scattering (SAXS), energy dispersive X-ray spectroscopy (EDX), and scanning acoustic microscopy (SAM). In cortical bone of Nf1Prx1 mice we detected ectopic blood vessels that were associated with diaphyseal mineralization defects. Defective mineral binding in the proximity of blood vessels was most likely due to impaired bone collagen formation, as these areas were completely devoid of acidic matrix proteins and contained thin collagen fibers. Additionally, we found significantly reduced mechanical strength of the bone material, which was partially caused by increased osteocyte volume. Consistent with these observations, bone samples from individuals with NF1 and tibial dysplasia showed increased osteocyte lacuna volume. Reduced mechanical properties were associated with diminished matrix stiffness, as determined by SAM. In line with these observations, bone tissue from individuals with NF1 and tibial dysplasia showed heterogeneous mineralization and reduced collagen fiber thickness and packaging. Collectively, the data indicate that bone fragility in NF1 tibial dysplasia is partly due to an increased osteocyte-related micro-porosity, hypomineralization, a generalized defect of organic matrix formation, exacerbated in the regions of tensional and bending force integration, and finally persistence of ectopic blood vessels associated with localized macro-porotic bone lesions.