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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Bouten, Cvc Carlijn
Eindhoven University of Technology
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (13/13 displayed)
- 2023How Smart are Smart Materials?citations
- 2020Optimization of Anti-kinking Designs for Vascular Grafts Based on Supramolecular Materialscitations
- 2020Imaging the In Vivo Degradation of Tissue Engineering Implants by Use of Supramolecular Radiopaque Biomaterialscitations
- 2019Macrophage-driven biomaterial degradation depends on scaffold microarchitecturecitations
- 2018Intrinsic cell stress is independent of organization in engineered cell sheetscitations
- 2017Biomaterial-driven in situ cardiovascular tissue engineering : a multi-disciplinary perspectivecitations
- 2017Porous scaffolds using dual electrospinning for in situ cardiovascular tissue engineeringcitations
- 2017Mechanically robust electrospun hydrogel scaffolds crosslinked via supramolecular interactionscitations
- 2015Hydrolytic and oxidative degradation of electrospun supramolecular biomaterialscitations
- 2015Hydrolytic and oxidative degradation of electrospun supramolecular biomaterials:In vitro degradation pathwayscitations
- 2014Monocytic cells become less compressible but more deformable upon activationcitations
- 2013Mechanical analysis of ovine and pediatric pulmonary artery for heart valve stent designcitations
- 2003Finite element model of mechanically induced collagen fiber synthesis and degradation in the aortic valvecitations
Places of action
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booksection
Porous scaffolds using dual electrospinning for in situ cardiovascular tissue engineering
Abstract
In situ cardiovascular tissue engineering is emerging as a promising approach for replacing diseased or damaged components of the cardiovascular system by the use of biodegradable synthetic grafts. Functional porous scaffolds are implanted to create in vivo complex tissues that are functionally similar to their native counterparts. A biodegradable starter matrix permits cell infiltration and tissue formation at the site of implantation, while maintaining tissue mechanical and biological function. This chapter elaborates on the fabrication of porous scaffolds via the electrospinning technique, including advantages, as well as limitations of various approaches, like single-nozzle, dual-nozzle, and coaxial-nozzle electrospinning. 442The added value of dual-nozzle electrospinning technique is highlighted, where scaffold porosity is enhanced by selectively removing one of the polymers while the other polymer maintains mechanical stability. Further, optimization techniques for modifying the porosity of electrospun scaffolds are described along with their influence on the graft’s mechanical properties and biodegradation rate.