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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Ahmed, S.
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Publications (8/8 displayed)
- 2024Recrystallization kinetics in 3D printed 316L stainless steelcitations
- 2023Additive manufacturing of flexible strain sensors based on smart composites for structural health monitoring with high accuracy and fidelitycitations
- 2022State-of-the-art biosynthesis of tin oxide nanoparticles by chemical precipitation method towards photocatalytic applicationcitations
- 2017Synthesis, characterization, density functional study and antimicrobial evaluation of a series of bischelated complexes with a dithiocarbazate Schiff base ligandcitations
- 2014Biodegradation of starch blended polyvinyl chloride films by isolated Phanerochaete chrysosporium PV1citations
- 2014Preparation and characterization of bioactive composites and fibers for dental applicationscitations
- 2013Development and characterization of novel polyurethane films impregnated with tolfenamic acid for therapeutic applicationscitations
- 2006Examination of the influence of boron on the microstructure and properties of low C ferritic steels using NanoSIMS and TEMcitations
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article
Development and characterization of novel polyurethane films impregnated with tolfenamic acid for therapeutic applications
Abstract
The present study deals with the preparation of polyurethane (PU) films impregnated with a nonsteroidal anti-inflammatory drug, tolfenamic acid (TA). Solvent evaporation technique has been employed for the preparation of TA-PU films in two different ratios of 1: 2 and 1: 5 in Tetrahydrofuran (THF) or THF-ethanol mixtures. The prepared films were characterized using X-Ray Diffraction (XRD), Differential Scanning Calorimetry (DSC), Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM), and release studies. The results indicate transformation of crystalline TA to its amorphous form. The degree of crystallinity changes both by increasing the polymer concentration and solvent used for the film preparations. The release profiles of TA were also found to be affected, showing a decrease from approximately 50% to 25% from 1: 2 to 1: 5 ratios, respectively. © 2013 Hilal Istanbullu et al.