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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Haghiri-Gosnet, Anne-Marie
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Topics
Publications (7/7 displayed)
- 2018Increasing the Efficiency of Amino Acids Detection by Electrochemical Methods on Amorphous Carbon Nitride a-CNx Electrodes
- 2018Influence of the atomic nitrogen content in amorphous carbon nitride thin films on the modulation of their polarizable interfaces propertiescitations
- 2014Improved electrochemical detection of a transthyretin synthetic peptide in the nanomolar range with a two-electrode system integrated in a glass/PDMS microchip.citations
- 2014Improved electrochemical detection of a transthyretin synthetic peptide in the nanomolar range with a two-electrode system integrated in a glass/PDMS microchip.citations
- 2011Photonic crystal patterning of luminescent sol-gel films for light extractioncitations
- 2000Thickness dependence of the stability of the charge-ordered state in Pr$_{0.5}$Ca$_{0.5}$MnO$_{3}$ thin films
- 2000Spectacular decrease of the melting magnetic field in the charge-ordered state of tensile Pr0.5Ca0.5MnO3 films
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article
Increasing the Efficiency of Amino Acids Detection by Electrochemical Methods on Amorphous Carbon Nitride a-CNx Electrodes
Abstract
Amorphous carbon nitride a-CNx thin films were elaborated on transparent and conductive glass/indium-tin oxide (ITO) wafers to improve the electroanalytical detection of transthyretin peptide (PN) and specific amino acids (AA) from its sequence which constitutes a great challenge for the diagnosis of transthyretin-related familial amyloïd polyneuropathy (ATTR). The naphthalene-2,3-dicarboxyaldehyde (NDA) label was used for the derivatization reaction of AAs to form N-2-substituted-1-cyanobenz-[f]-isoindole derivatives (CBI) which are both fluorescent and electroactive. The charge transfer resistance for all CBI derivatives permits to distinguish one AA from others, while no discrimination could be obtained using cyclic voltammetry where the peak potentials oxidation are too close enough.