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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Sun, Tao
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Publications (7/7 displayed)
- 2022In Situ X-ray Radiography and Computational Modeling to Predict Grain Morphology in β-Titanium during Simulated Additive Manufacturingcitations
- 2022Resolving the Martensitic Transformation in Q&P Steels <em>In-Situ</em> at Dynamic Strain Rates Using Synchrotron X-ray Diffractioncitations
- 2021In-Situ Characterization of Pore Formation Dynamics in Pulsed Wave Laser Powder Bed Fusioncitations
- 2021Synthesis of bulk reactive Ni–Al composites using high pressure torsioncitations
- 2016PEDOT:PSS-Containing Nanohydroxyapatite/Chitosan Conductive Bionanocomposite Scaffold: Fabrication and Evaluationcitations
- 2008Analytical and numerical modeling methods for impedance analysis of single cells on-chipcitations
- 2002Polyethylene-layered silicate nanocomposites prepared by the polymerization-filling technique: synthesis and mechanical propertiescitations
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article
Analytical and numerical modeling methods for impedance analysis of single cells on-chip
Abstract
Electrical impedance spectroscopy (EIS) is a noninvasive method for characterizing the dielectric properties of biological particles. The technique can differentiate between cell types and provide information on cell properties through measurement of the permittivity and conductivity of the cell membrane and cytoplasm. In terms of lab-on-a-chip (LOC) technology, cells pass sequentially through the microfluidic channel at high speed and are analyzed individually, rather than as traditionally done on a mixture of particles in suspension. This paper describes the analytical and numerical modeling methods for EIS of single cell analysis in a microfluidic cytometer. The presented modeling methods include Maxwell’s mixture theory, equivalent circuit model and finite element method. The difference and advantages of these methods have been discussed. The modeling work has covered the static case — an immobilized cell in suspension and the dynamic case — a moving cell in the channel.