| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Roos, Malgorzata
University of Zurich
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (7/7 displayed)
- 2021Is the high-performance thermoplastic polyetheretherketone indicated as a clasp material for removable dental prostheses?citations
- 2018Reliability of wear measurements of CAD-CAM restorative materials after artificial aging in a mastication simulatorcitations
- 2018Bonding of composite resins to PEEK: the influence of adhesive systems and air-abrasion parameters
- 2016Spectrophotometric Evaluation of Polyetheretherketone (PEEK) as a Core Material and a Comparison with Gold Standard Core Materialscitations
- 2015The Resistant-Population Cutoff (RCOFF): a New Concept for Improved Characterization of Antimicrobial Susceptibility Patterns of Non-Wild-Type Bacterial Populationscitations
- 2014Zirconia ceramics, their contrast ratio and grain size depending on sintering parameters
- 2013Two-body wear of monolithic, veneered and glazed zirconia and their corresponding enamel antagonistscitations
Places of action
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article
The Resistant-Population Cutoff (RCOFF): a New Concept for Improved Characterization of Antimicrobial Susceptibility Patterns of Non-Wild-Type Bacterial Populations
Abstract
<jats:title>ABSTRACT</jats:title><jats:p>This study aimed to determine resistant-population cutoffs (RCOFFs) to allow for improved characterization of antimicrobial susceptibility patterns in bacterial populations. RCOFFs can complement epidemiological cutoff (ECOFF)-based settings of clinical breakpoints (CBPs) by systematically describing the correlation between non-wild-type and wild-type populations. We illustrate this concept by describing three paradigmatic examples of wild-type and non-wild-type<jats:named-content content-type="genus-species">Escherichia coli</jats:named-content>populations from our clinical strain database of disk diffusion diameters. The statistical determination of RCOFFs and ECOFFs and their standardized applications in antimicrobial susceptibility testing (AST) facilitates the assignment of isolates to wild-type or non-wild-type populations. This should improve the correlation of<jats:italic>in vitro</jats:italic>AST data and distinct antibiotic resistance mechanisms with clinical outcome facilitating the setting and validation of CBPs.</jats:p>