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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Engelhardt, Kathrin
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article
First Survey of Metallo-β-Lactamases in Clinical Isolates of <i>Pseudomonas aeruginosa</i> in a German University Hospital
Abstract
<jats:title>ABSTRACT</jats:title><jats:p>A total of 489 clinical isolates of<jats:italic>Pseudomonas aeruginosa</jats:italic>was investigated for metallo-β-lactamase (MBL) production. Molecular analysis detected a<jats:italic>bla</jats:italic><jats:sub>VIM-1</jats:sub>gene in the chromosome of one isolate and a<jats:italic>bla</jats:italic><jats:sub>VIM-2</jats:sub>gene carried on the plasmid in seven isolates. Moreover, we showed that an initial screening by combined susceptibility testing of imipenem and ceftazidime followed by a confirmatory EDTA combination disk test represents a valid alternative to the molecular investigation of MBL genes, making MBL detection possible in routine diagnostic laboratories.</jats:p>