| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Harrington, Matthew J.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (9/9 displayed)
- 2023The Internal Structure of the Velvet Worm Projectile Slime: A Small-Angle Scattering Study.citations
- 2022Mistletoe viscin: a hygro- and mechano-responsive cellulose-based adhesive for diverse material applicationscitations
- 2021Microfluidic-like fabrication of metal ion–cured bioadhesives by musselscitations
- 2021Natural load-bearing protein materialscitations
- 2018Metal-Tunable Self-Assembly of Hierarchical Structure in Mussel-Inspired Peptide Filmscitations
- 2017Rapid self-assembly of complex biomolecular architectures during mussel byssus biofabricationcitations
- 2014The Mechanical Role of Metal Ions in Biogenic Protein-Based Materialscitations
- 2014The role of topology and thermal backbone fluctuations on sacrificial bond efficacy in mechanical metalloproteinscitations
- 2014Influence of sacrificial bonds on the mechanical behaviour of polymer chainscitations
Places of action
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article
Microfluidic-like fabrication of metal ion–cured bioadhesives by mussels
Abstract
<p>To anchor in seashore habitats, mussels fabricate adhesive byssus fibers that are mechanically reinforced by protein-metal coordination mediated by 3,4-dihydroxyphenylalanine (DOPA). The mechanism by which metal ions are integrated during byssus formation remains unknown. In this study, we investigated the byssus formation process in the blue mussel, Mytilus edulis, combining traditional and advanced methods to identify how and when metals are incorporated. Mussels store iron and vanadium ions in intracellular metal storage particles (MSPs) complexed with previously unknown catechol-based biomolecules. During adhesive formation, stockpiled secretory vesicles containing concentrated fluid proteins are mixed with MSPs within a microfluidic-like network of interconnected channels where they coalesce, forming protein-metal bonds within the nascent byssus. These findings advance our understanding of metal use in biological materials with implications for next-generation metallopolymers and adhesives.</p>