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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Hämäläinen, Jani Marko Antero
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Topics
Publications (20/20 displayed)
- 2020Van der Waals epitaxy of continuous thin films of 2D materials using atomic layer deposition in low temperature and low vacuum conditionscitations
- 2019How insignificant modifications of photocatalysts can significantly change their photocatalytic activitycitations
- 2018Rhenium Metal and Rhenium Nitride Thin Films Grown by Atomic Layer Depositioncitations
- 2018Atomic Layer Deposition of Rhenium Disulfidecitations
- 2016Atomic Layer Deposition of Metal Phosphates and Lithium Silicates
- 2016Atomic Layer Deposition of Iridium Thin Films Using Sequential Oxygen and Hydrogen Pulsescitations
- 2016Nucleation and conformality of iridium and iridium oxide thin films grown by atomic layer depositioncitations
- 2014Atomic Layer Deposition of Noble Metals and Their Oxidescitations
- 2013Low temperature atomic layer deposition of noble metals using ozone and molecular hydrogen as reactantscitations
- 2012Study of amorphous lithium silicate thin films grown by atomic layer depositioncitations
- 2012Lithium Phosphate Thin Films Grown by Atomic Layer Depositioncitations
- 2012Atomic layer deposited iridium oxide thin film as microelectrode coating in stem cell applicationscitations
- 2011Iridium metal and iridium oxide thin films grown by atomic layer deposition at low temperaturescitations
- 2011Atomic Layer Deposition and Characterization of Aluminum Silicate Thin Films for Optical Applicationscitations
- 2010pH electrode based on ALD deposited iridium oxidecitations
- 2009Metallic Ir, IrO2 and Pt Nanotubes and Fibers by Electrospinning and Atomic Layer Deposition
- 2009Study on atomic layer deposition of amorphous rhodium oxide thin filmscitations
- 2009Atomic layer deposition of iridium thin films by consecutive oxidation and reduction stepscitations
- 2008Atomic layer deposition of iridium oxide thin films from Ir(acac)₃ and ozonecitations
- 2008Atomic layer deposition of platinum oxide and metallic platinum thin films from Pt(acac)₂ and ozonecitations
Places of action
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article
Atomic layer deposited iridium oxide thin film as microelectrode coating in stem cell applications
Abstract
Microelectrodes of microelectrode arrays (MEAs) used in cellular electrophysiology studies were coated with iridium oxide (IrOx) thin film using atomic layer deposition (ALD). This work was motivated by the need to find a practical alternative to commercially used titanium nitride (TiN) microelectrode coating. The advantages of ALD IrOx coating include decreased impedance and noise levels and improved stimulation capability of the microelectrodes compared to uncoated microelectrodes. The authors’ process also takes advantage of ALD’s exact process control and relatively low source material start costs compared to traditionally used sputtering and electrochemical methods. Biocompatibility and suitability of ALD IrOx microelectrodes for stem cell research applications were verified by culturing human embryonic stem cell derived neuronal cells for 28 days on ALD IrOx MEAs and successfully measuring electrical activity of the cell network. Electrode impedance of 450 kΩ at 1 kHz was achieved with ALD IrOx in the authors’ 30 μm microelectrodes. This is better than that reported for any uncoated microelectrodes with equal size, even equal to that of inactivated sputtered IrOx coating. Also, stimulation capability was demonstrated. However, further development, including, e.g., applying electrochemical activation, is needed to achieve the performance of commercial TiN-coated microelectrodes.