| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Biernat, Monika
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (10/10 displayed)
- 2023The effect of extrusion and injection molding on physical, chemical, and biological properties of PLLA/HAp whiskers compositescitations
- 2022The Preliminary Assessment of New Biomaterials Necessitates a Comparison of Direct and Indirect Cytotoxicity Methodological Approachescitations
- 2022Effects of Sterilization and Hydrolytic Degradation on the Structure, Morphology and Compressive Strength of Polylactide-Hydroxyapatite Compositescitations
- 2022Dual Modification of Porous Ca-P/PLA Composites with APTES and Alendronate Improves Their Mechanical Strength and Cytobiocompatibility towards Human Osteoblastscitations
- 2021The Effect of Pore Size Distribution and l-Lysine Modified Apatite Whiskers (HAP) on Osteoblasts Response in PLLA/HAP Foam Scaffolds Obtained in the Thermally Induced Phase Separation Processcitations
- 2021Three Component Composite Scaffolds Based on PCL, Hydroxyapatite, and L-Lysine Obtained in TIPS-SL: Bioactive Material for Bone Tissue Engineeringcitations
- 2019The studies of cytotoxicity and antibacterial activity of composites with ZnO-doped bioglasscitations
- 2019Influence of low-temperature reaction time on morphology and phase composition of short calcium phosphate whiskerscitations
- 2017Controlling the microstructure of lyophilized porous biocomposites by the addition of ZnO-doped bioglasscitations
- 2016Orientation and biorecognition of immunoglobulin adsorbed on spin-cast poly(3-alkylthiophenes) : impact of polymer film crystallinitycitations
Places of action
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article
The studies of cytotoxicity and antibacterial activity of composites with ZnO-doped bioglass
Abstract
The paper presents results of the studies on porous composites obtained using lyophilization method based on the solutions of the following polymers: chitosan, sodium alginate and polylactide, as well as ZnO‐doped CaO–SiO2–P2O5 bioglass. The researchers took the advantage of zinc ions demonstrating the bactericidal, immune‐stimulating, and tissue‐regenerating functions in the organism. The cytotoxicity of the composites was tested on L929 cells by means of the direct and the indirect contact method. The antibacterial properties were determined against the gram‐negative bacteria Pseudomonas aeruginosa and the gram‐positive bacteria Staphylococcus aureus at 24, 48 hours, and 7 days. The study demonstrated that changes due to cytotoxicity effect of the composites depend on the type of polymer and on the duration of contact with cells. The composite with polylactide was found to be the least toxic for L929 cells. ZnO added to the chemical composition of bioglass ensured bactericidal effects. The antibacterial properties of the composites depended on the ZnO content, bioglass grain size, polymer type, and composite microstructure. The composites presented in this paper are innovative as biomaterials for filling bone cavities because they can be a matrix for cells and have an antibacterial effect while supporting the regeneration of damaged tissue.