| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Sharma, Prashant K.
University Medical Center Groningen
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (17/17 displayed)
- 2023Modulating the water behavior, microstructure, and viscoelasticity of plasma-derived hydrogels by adding silica nanoparticles with tailored chemical and colloidal propertiescitations
- 2022Viscoelastic properties of plasma-agarose hydrogels dictate favorable fibroblast responses for skin tissue engineering applicationscitations
- 2021Chemical and mechanical influence of root canal irrigation on biofilm removal from lateral morphological features of simulated root canals, dentine discs and dentinal tubulescitations
- 2019Chemical biofilm removal capacity of endodontic irrigants as a function of biofilm structurecitations
- 2019Chemical efficacy of several NaOCl concentrations on biofilms of different architecturecitations
- 2019Factors affecting the chemical efficacy of 2% sodium hypochlorite against oral steady-state dual-species biofilmscitations
- 2018Notochordal cell matrix as a bioactive lubricant for the osteoarthritic jointcitations
- 2017Implant Failurecitations
- 2013Stress relaxation analysis facilitates a quantitative approach towards antimicrobial penetration into biofilmscitations
- 2013A Distinguishable Role of eDNA in the Viscoelastic Relaxation of Biofilmscitations
- 2009Tunable Visible Emission of Ag-Doped CdZnS Alloy Quantum Dots
- 2009Bacterial Adhesion to Diamond-like Carbon as Compared to Stainless Steelcitations
- 2009Hyphal content determines the compression strength of Candida albicans biofilmscitations
- 2008Physicochemical and microbial fouling characterization of novel, extremely hydrophobic, nanocomposite diamond like carbon polymer hybrid coatings
- 2007Low-load compression testingcitations
- 2007Low-load compression testing:a novel way of measuring biofilm thicknesscitations
- 2001Surface chemical characterisation of Paenibacillus polymyxa before and after adaptation to sulfide mineralscitations
Places of action
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article
Factors affecting the chemical efficacy of 2% sodium hypochlorite against oral steady-state dual-species biofilms
Abstract
<p>Aim To study the influence of time and volume of 2% sodium hypochlorite (NaOCl) on biofilm removal and to investigate the changes induced on the biofilm architecture. Steady-state, dual-species biofilms of standardized thickness and a realistic contact surface area between biofilms and NaOCl were used. Methodology Streptococcus oralis J22 and Actinomyces naeslundii T14V-J1 biofilms were grown on saliva-coated hydroxyapatite discs within sample holders in the Constant Depth Film Fermenter (CDFF) for 96 h. Two per cent NaOCl was statically applied for three different time intervals (60, 120 and 300 s) and in two different volumes (20 and 40 mu L) over the biofilm samples. The diffusion-driven effects of time and volume on biofilm disruption and dissolution were assessed with Optical Coherence Tomography (OCT). Structural changes of the biofilms treated with 2% NaOCl were studied with Confocal Laser Scanning Microscopy (CLSM) and Low Load Compression Testing (LLCT). A two-way analysis of variance (2-way anova) was performed, enabling the effect of each independent variable as well as their interaction on the outcome measures. Results Optical coherence tomography revealed that by increasing the exposure time and volume of 2% NaOCl, both biofilm disruption and dissolution significantly increased. Analysis of the interaction between the two independent variables revealed that by increasing the volume of 2% NaOCl, significant biofilm dissolution could be achieved in less time. Examination of the architecture of the remaining biofilms corroborated the EPS-lytic action of 2% NaOCl, especially when greater volumes were applied. The viscoelastic analysis of the 2% NaOCl-treated biofilms revealed that the preceding application of higher volumes could impact their subsequent removal. Conclusions Time and volume of 2% NaOCl application should be taken into account for maximizing the anti-biofilm efficiency of the irrigant and devising targeted disinfecting regimes against remaining biofilms.</p>