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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Kosel, Jürgen
Laboratori Guglielmo Marconi (Italy)
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (32/32 displayed)
- 2018Development of printed sensors for shoe sensing applicationscitations
- 2017Magnetic composite Hydrodynamic Pump with Laser Induced Graphene Electrodescitations
- 2017Sensing system for salinity testing using laser-induced graphene sensorscitations
- 2017Current induced domain wall motion in cylindrical nanowires
- 2017Scalable high-affinity stabilization of magnetic iron oxide nanostructures by a biocompatible antifouling homopolymercitations
- 2016Magnetically Triggered Monodispersed Nanocomposite Fabricated by Microfluidic Approach for Drug Deliverycitations
- 2016A Magnetoresistive Tactile Sensor for Harsh Environment Applicationscitations
- 2016Piezoelectric transducer array microspeakercitations
- 2016Highly Efficient Thermoresponsive Nanocomposite for Controlled Release Applicationscitations
- 2016Flexible carbon nanotube nanocomposite sensor for multiple physiological parameter monitoringcitations
- 2016Magnetic Nanocomposite Cilia Energy Harvestercitations
- 2016Fabrication and characterization of magnetic composite membrane pressure sensorcitations
- 2016Tunable magnetic nanowires for biomedical and harsh environment applicationscitations
- 2016A single magnetic nanocomposite cilia force sensorcitations
- 2016Magnetic nanocomposite sensor
- 2016Magnetic Tactile Sensor for Braille Readingcitations
- 2015Magnetic Nanocomposite Cilia Tactile Sensorcitations
- 2015Biomimetic magnetic nanocomposite for smart skinscitations
- 2015Magnetoelectric polymer nanocomposite for flexible electronicscitations
- 2015Fabrication and properties of multiferroic nanocomposite filmscitations
- 2015Electromagnetically powered electrolytic pump and thermo-responsive valve for drug deliverycitations
- 2015Magnetic micropillar sensors for force sensingcitations
- 2015Rapid and molecular selective electrochemical sensing of phthalates in aqueous solutioncitations
- 2015Osmotically driven drug delivery through remote-controlled magnetic nanocomposite membranescitations
- 2014Magnetic polymer nanocomposites for sensing applicationscitations
- 2014Introducing molecular selectivity in rapid impedimetric sensing of phthalatescitations
- 2014A magnetic nanocomposite for biomimetic flow sensingcitations
- 2013Fabrication and properties of SmFe2-PZT magnetoelectric thin filmscitations
- 2013Integrated passive and wireless sensor for magnetic fields, temperature and humiditycitations
- 2013Technique for rapid detection of phthalates in water and beveragescitations
- 2012Microfabrication of magnetostrictive beams based on NiFe film doped with B and Mo for integrated sensor systemscitations
- 2012Optimization of autonomous magnetic field sensor consisting of giant magnetoimpedance sensor and surface acoustic wave transducercitations
Places of action
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document
Electromagnetically powered electrolytic pump and thermo-responsive valve for drug delivery
Abstract
A novel drug delivery device is presented, implementing an electrolytic pump and a thermo-responsive valve. The device is remotely operated by an AC electromagnetic field (40.5∼58.5 mT, 450 kHz) that provides the power for the pump and the valve. It is suitable for long-term therapy applications, which use a solid drug in reservoir (SDR) approach and avoids unwanted drug diffusion. When the electromagnetic field is on, the electrolytic pump drives the drug towards the valve. The valve is made of a magnetic composite consisting of a smart hydrogel: Poly (N-Isopropylacrylamide) (PNIPAm) and iron powder. The heat generated in the iron powder via magnetic losses causes the PNIPAm to shrink, allowing the drug to flow past it. When the electromagnetic field is off, the PNIPAm swells, sealing the outlet. In the meantime, the bubbles generated by electrolysis recombine into water, causing a pressure reduction in the pumping chamber. This draws fresh fluid from outside the pump into the drug reservoir before the valve is fully sealed. The recombination can be accelerated by a platinum (Pt) coated catalytic reformer, allowing more fluid to flow back to the drug reservoir and dissolve the drug. By repeatedly turning on and off the magnetic field, the drug solution can be delivered cyclically. © 2015 IEEE.