| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Kruger, Marlena
in Cooperation with on an Cooperation-Score of 37%
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Publications (4/4 displayed)
- 2018Molecularly imprinted polymer-based electrochemical biosensor for bone loss detectioncitations
- 2017A novel electrochemical biosensor for bone turnover detection based on molecular imprinting technology
- 2016Development of molecular imprinted polymer interdigital sensor for C-terminal telopeptide of type I collagencitations
- 2015Development of a sensing system to detect C-telopeptide of type-I collagencitations
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document
A novel electrochemical biosensor for bone turnover detection based on molecular imprinting technology
Abstract
<p>This research reports a novel label-free sensing method for the measurement of C-telopeptide of Type-I collagen (CTX-1) in order to monitor bone turnover at an early stage. An interdigital sensor jointly with Electrochemical Impedance Spectroscopy (EIS) was used to study the resistive and capacitive properties of samples. Molecular Imprinted Polymers (MIPs) containing recognition sites for CTX-1 molecules were synthesized. The sensor was coated with the prepared MIPs to increase the sensitivity of the sensor to CTX-1. Different known concentration samples were tested and the sensitivity curve was plotted. The Nyquist fitted Curve and its equivalent Randle's circuit was estimated using a complex non-linear least square method (CNLS). The initial results are promising for further development of an inexpensive and portable device for early detection of bone turnover, so therapy can be started earlier.</p>