| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Hursthouse, M. B.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (10/10 displayed)
- 2010Seven 3-methylidene-1H-indol-2(3H)-ones related to the multiple-receptor tyrosine kinase inhibitor sunitinibcitations
- 2008A catemer-to-dimer structural transformation in cyheptamidecitations
- 2007The role of functional nitro and cyano groups in the self-assembly of 1,3-dithiole-2-thione-halogen adductscitations
- 2006New pyridyl modified phosphines: Synthesis and late transition-metal coordination studiescitations
- 2006The formation and isolation of benzisothiazole rings from the reactions of oxime-thiophenolate ligandscitations
- 2005Structures and physical properties of new ??-BEDT-TTF tris-oxalatometallate (III) salts containing chlorobenzene and halomethane guest moleculescitations
- 2003Synthesis and characterisation of a series of Group 7 metal 2,2,2,2-dicarbonylbis(triorganophosphine)-arachno-2-metallatetraboranes, M(CO)(2)L-2(B3H8) (M=Re, Mn); crystal and molecular structures of Re(CO)(2)(dppf)(B3H8) and Mn(CO)(2)(dppe)(B3H8)citations
- 2003The characterisation of lead fatty acid soaps in 'protrusions' in aged traditional oil paint.citations
- 2003Hybrid (Te, N) and (N, Te, N) ligands having pyrrolidine ring and their palladium(II) and mercury(II) complexes: synthesis and crystal structurescitations
- 2003First example of bimetallic complex of platinum(II) with a hybrid organotellurium ligand [(4-MeOC6H4Te)CH2CH2OCH2CH2CH2(2-C5H4N)] (L1) containing 20-membered metallomacrocycle ring: synthesis and crystal structurecitations
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article
Seven 3-methylidene-1H-indol-2(3H)-ones related to the multiple-receptor tyrosine kinase inhibitor sunitinib
Abstract
The solid-state structures of a series of seven substituted 3-methylidene-1H-indol-2(3H)-one derivatives have been determined by single-crystal X-ray diffraction and are compared in detail. Six of the structures {(3Z)-3-(1H-pyrrol-2- ylmethylidene)-1H-indol-2(3H)-one, C(13)H(10)N(2)O, (2a); (3Z)-3-( 2-thienylmethylidene)-1H-indol-2(3H)-one, C(13)H(9)NOS, (2b); (3E)-3-(2-furylmethylidene)-1H-indol-2(3H)-one monohydrate, C(13)H(9)NO(2)center dot H(2)O, (3a); 3-(1-methylethylidene)-1H-indol- 2(3H)-one, C(11)H(11)NO, (4a); 3-cyclohexylidene-1H-indol- 2(3H)-one, C(14)H(15)NO, (4c); and spiro[1,3-dioxane-2,3'-indolin]- 2'-one, C(11)H(11)NO(3), (5)} display, as expected, intermolecular hydrogen bonding (N-H center dot center dot center dot O=C) between the 1H-indol-2(3H)-one units. However, methyl 3-(1-methylethylidene)- 2-oxo-2,3-dihydro-1H-indole-1-carboxylate, C(13)H(13)NO(3), (4b), a carbamate analogue of (4a) lacking an N-H bond, displays no intermolecular hydrogen bonding. The structure of (4a) contains three molecules in the asymmetric unit, while (4b) and (4c) both contain two independent molecules.