• Robert, Jerome

Abstract

<jats:p><jats:bold>Introduction.</jats:bold><jats:italic><jats:named-content content-type="species"><jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.6269" xlink:type="simple">Corynebacterium striatum</jats:ext-link></jats:named-content></jats:italic> is a non-<jats:italic>Diphteriae</jats:italic> commensal bacterium with a wide range of pathogenicity. The identification of multidrug-resistant (MDR) <jats:italic><jats:named-content content-type="species"><jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.6269" xlink:type="simple">C. striatum</jats:ext-link></jats:named-content></jats:italic> is concerning because drug susceptibility testing is not usually performed in microbiology laboratories. There is no consensus yet on the treatment of septic thrombophlebitis in this situation.</jats:p><jats:p><jats:bold>Case report.</jats:bold> We report here the first case of a quinquagenarian patient with a history of AIDS and fungic endocarditis, who was diagnosed with a nosocomial thrombophlebitis in the right jugular vein caused by <jats:italic><jats:named-content content-type="species"><jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.6269" xlink:type="simple">C. striatum</jats:ext-link></jats:named-content></jats:italic>. Bitherapy with daptomycin for 12 days and linezolid for 23 days was combined with a therapeutic anticoagulant. The follow-up included weekly cervical ultrasound controls. The efficiency of the treatment and the stability of the lesions allowed us to alleviate the medication with a prophylactic dose of anticoagulant. The patient was discharged from hospital and showed no signs of recurrence after 12 months.</jats:p><jats:p><jats:bold>Conclusion.</jats:bold> The lack of consensus relative to the management of septic thrombophlebitis precludes the validation of a specific treatment for the condition. Our results suggest that a combination that includes removal of the medical device is needed. A total of 6 weeks of antibiotherapy should be applied, starting with 2 weeks of vancomycin or a combination of antibiotitherapy with daptomycin in order to reduce the bacterial load and avoid resistance. Six weeks of anticoagulation therapy is effective.</jats:p>

Topics

• impedance spectroscopy
• susceptibility