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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Basu, Bikramjit
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (26/26 displayed)
- 2024Gelatin Methacryloyl (GelMA) - 45S5 Bioactive Glass (BG) Composites for Bone Tissue Engineering: 3D Extrusion Printability and Cytocompatibility Assessment Using Human Osteoblastscitations
- 2023Biomaterial strategies to combat implant infections: new perspectives to old challengescitations
- 2022In silico study on probing atomistic insights into structural stability and tensile properties of Fe-doped hydroxyapatite single crystalscitations
- 2019HDPE/UHMWPE hybrid nanocomposites with surface functionalized graphene oxide towards improved strength and cytocompatibilitycitations
- 2018Competition between densification and microstructure development during spark plasma sintering of B4C–Eu2O3citations
- 2017Competing Roles of Substrate Composition, Microstructure, and Sustained Strontium Release in Directing Osteogenic Differentiation of hMSCscitations
- 2016Low temperature additive manufacturing of three dimensional scaffolds for bone-tissue engineering applicationscitations
- 2016Inhibitory effect of direct electric field and HA-ZnO composites on S. aureus biofilm formationcitations
- 2015Structural and magnetic phase transformations of hydroxyapatite-magnetite composites under inert and ambient sintering atmospherescitations
- 2013Nanomaterials Processed by Spark Plasma Sinteringcitations
- 2011An X-ray micro-fluorescence study to investigate the distribution of Al, Si, P and Ca ions in the surrounding soft tissue after implantation of a calcium phosphate-mullite ceramic composite in a rabbit animal modelcitations
- 2005Processing and mechanical properties of ZrO2-TiB2 compositescitations
- 2004Microstructure-toughness-wear relationship of tetragonal zirconia ceramicscitations
- 2004Transformation behaviour of tetragonal zirconia: role of dopant content and distributioncitations
- 2004ZrO2-Al2O3 composites with tailored toughnesscitations
- 2003Unlubricated tribological performance of advanced ceramics and composites at fretting contacts with aluminacitations
- 2003Friction and wear behaviour of SiAlON ceramics under fretting contactscitations
- 2003Transformation-induced damping behaviour of Y-TZP zirconia ceramicscitations
- 2002Fretting wear of self-mated tetragonal zirconia ceramics in different humidity
- 2002Unlubricated fretting wear of TiB2-containing composites against bearing steelcitations
- 2002Development of ZrO2-ZrB2 compositescitations
- 2002Y-TZP ceramics with tailored toughness
- 2002Toughness optimisation of ZrO2-TiB2 composites
- 2001Transformation behavior of yttria stabilized tetragonal zirconia polycrystal-TiB2 compositescitations
- 2001Fretting wear behavior of TiB2-based materials against bearing steel under water and oil lubricationcitations
- 2000Influence of humidity on the fretting wear of self-mated tetragonal zirconia ceramicscitations
Places of action
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article
HDPE/UHMWPE hybrid nanocomposites with surface functionalized graphene oxide towards improved strength and cytocompatibility
Abstract
<jats:p>High-density polyethylene (HDPE)-based and ultra-high molecular weight polyethylene (UHMWPE)-based composites with carbonaceous reinforcements are being widely investigated for biomedical applications. The enhancement of material properties critically depends on the nature, amount and compatibility of the reinforcement with the polymeric matrix. To this end, this study demonstrates the efficacy of a ‘dual’ hybrid approach of incorporating modified inorganic nanofiller into an optimized polyethylene blend. In particular, a unique synthesis strategy was adopted to design a covalently bonded maleated polyethylene (mPE) grafted modified graphene oxide (mGO) hybrid nanocomposite. In this scheme, polyethyleneimine (PEI) was initially attached onto GO to synthesize amine functionalized GO (GO–PEI). This is followed by mPE grafting, resulting in mGO. Melt-extrusion together with injection moulding of a polymer mix (60% HDPE–40% UHMWPE) with different proportions (less than or equal to 3 wt%) of surface functionalized GO was conducted to develop nanocomposites of different sizes and shapes. When compared with unreinforced PE blend, the nanocomposites with 1 wt% mGO exhibited an increase in ultimate tensile strength by 120% (up to 65 MPa) and elastic modulus by 40% (up to 908 MPa). The uniform dispersion of modified GO nanofillers, confirmed using X-ray micro-computed tomography and transmission electron microscopy, facilitated effective interfacial adhesion and compatibility with the hybrid polymer matrix. The variation in mechanical properties with GO/mGO addition to PE blend was critically discussed in reference to the structural modification of GO, crystallinity and nature of dispersion of fillers. Importantly, the nanocomposites support the attachment and proliferation of C2C12 murine myoblast cells over 3 days in culture in a statistically insignificant manner with respect to polymer blends without any nanofiller. Taken together, the experimental results suggest that HDPE/UHMWPE/mGO is a promising biomaterial for bone tissue engineering applications.</jats:p>