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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Witek, Lukasz
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (42/42 displayed)
- 20233D Printing Type 1 Bovine Collagen Scaffolds for Tissue Engineering Applications—Physicochemical Characterization and In Vitro Evaluationcitations
- 2023Engineering 3D Printed Bioceramic Scaffolds to Reconstruct Critical-Sized Calvaria Defects in a Skeletally Immature Pig Modelcitations
- 2023Three-Dimensional Printing Bioceramic Scaffolds Using Direct-Ink-Writing for Craniomaxillofacial Bone Regeneration. citations
- 2022Residual stress estimated by nanoindentation in pontics and abutments of veneered zirconia fixed dental prosthesescitations
- 2022Physiochemical and bactericidal activity evaluationcitations
- 2022Temporary materials used in prosthodonticscitations
- 2022Stability of fatigued and aged ZTA compared to 3Y-TZP and Al2O3 ceramic systemscitations
- 2021Three-Dimensionally-Printed Bioactive Ceramic Scaffoldscitations
- 2021Nanoscale physico-mechanical properties of an aging resistant ZTA compositecitations
- 2021Effect of supplemental acid-etching on the early stages of osseointegrationcitations
- 2021Hydrothermal aging affects the three-dimensional fit and fatigue lifetime of zirconia abutmentscitations
- 2020Comparative analysis of elastomeric die materials for semidirect composite restorations.
- 2020Bone Tissue Engineering in the Growing Calvaria Using Dipyridamole-Coated, Three-Dimensionally-Printed Bioceramic Scaffoldscitations
- 2020Comparative analysis of elastomeric die materials for semidirect composite restorations
- 2020Microstructural, mechanical, and optical characterization of an experimental aging-resistant zirconia-toughened alumina (ZTA) compositecitations
- 2020Assessing osseointegration of metallic implants with boronized surface treatmentcitations
- 2020Aging resistant ZTA composite for dental applicationscitations
- 2019Long-term outcomes of 3D-printed bioactive ceramic scaffolds for regeneration of the pediatric skeleton
- 2019Osteointegrative and microgeometric comparison between micro-blasted and alumina blasting/acid etching on grade II and V titanium alloys (Ti-6Al-4V)citations
- 2019Physical and chemical characterization of synthetic bone mineral ink for robocasting applications
- 2019Dipyridamole Augments Three-Dimensionally Printed Bioactive Ceramic Scaffolds to Regenerate Craniofacial Bonecitations
- 2019Tissue-engineered alloplastic scaffolds for reconstruction of alveolar defectscitations
- 2019Comparative in vitro study of 3D robocasting scaffolds using beta tricalcium phosphate and synthetic bone mineral
- 2019Synergistic effects of implant macrogeometry and surface physicochemical modifications on osseointegrationcitations
- 2019Repair of Critical-Sized Long Bone Defects Using Dipyridamole-Augmented 3D-Printed Bioactive Ceramic Scaffoldscitations
- 2019Nanomechanical and microstructural characterization of a zirconia-toughened alumina composite after agingcitations
- 2019Dipyridamole-loaded 3D-printed bioceramic scaffolds stimulate pediatric bone regeneration in vivo without disruption of craniofacial growth through facial maturitycitations
- 2019Regeneration of a Pediatric Alveolar Cleft Model Using Three-Dimensionally Printed Bioceramic Scaffolds and Osteogenic Agentscitations
- 2018Form and functional repair of long bone using 3D-printed bioactive scaffoldscitations
- 2018Dipyridamole enhances osteogenesis of three-dimensionally printed bioactive ceramic scaffolds in calvarial defectscitations
- 2018Three dimensionally printed bioactive ceramic scaffold osseoconduction across critical-sized mandibular defectscitations
- 2017Controlling calcium and phosphate ion release of 3D printed bioactive ceramic scaffoldscitations
- 2017Biocompatibility and degradation properties of WE43 Mg alloys with and without heat treatmentcitations
- 2017Abstract 47. Dipyridamole-Containing 3D-Printed Bioactive Ceramic Scaffolds for the Treatment of Calvarial Defects
- 2015Geometrical versus Random beta-TCP Scaffolds: Exploring the Effects on Schwann Cell Growth and Behaviorcitations
- 2014The physicochemical characterization and in vivo response of micro/nanoporous bioactive ceramic particulate bone graft materialscitations
- 2014The in vivo effect of P-15 coating on early osseointegrationcitations
- 2013MicroCT analysis of a retrieved root restored with a bonded fiber-reinforced composite dowelcitations
- 2012Physicochemical characterization and in vivo evaluation of amorphous and partially crystalline calcium phosphate coatings fabricated on Ti-6Al-4V implants by the plasma spray methodcitations
- 2012Abutment Design for Implant-Supported Indirect Composite Molar Crownscitations
- 2012Characterization and in vivo evaluation of laser sintered dental endosseous implants in dogscitations
- 2011Additive CAD/CAM process for dental prosthesescitations
Places of action
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article
Bone Tissue Engineering in the Growing Calvaria Using Dipyridamole-Coated, Three-Dimensionally-Printed Bioceramic Scaffolds
Abstract
<p>BACKGROUND: Three-dimensionally-printed bioceramic scaffolds composed of β-tricalcium phosphate delivering the osteogenic agent dipyridamole can heal critically sized calvarial defects in skeletally mature translational models. However, this construct has yet to be applied to growing craniofacial models. In this study, the authors implanted three-dimensionally-printed bioceramic/dipyridamole scaffolds in a growing calvaria animal model and evaluated bone growth as a function of geometric scaffold design and dipyridamole concentration. Potential adverse effects on the growing suture were also evaluated. METHODS: Bilateral calvarial defects (10 mm) were created in 5-week-old (approximately 1.1 kg) New Zealand White rabbits (n = 16 analyzed). Three-dimensionally-printed bioceramic scaffolds were constructed in quadrant form composed of varying pore dimensions (220, 330, and 500 μm). Each scaffold was coated with collagen and soaked in varying concentrations of dipyridamole (100, 1000, and 10,000 μM). Controls consisted of empty defects. Animals were killed 8 weeks postoperatively. Calvariae were analyzed using micro-computed tomography, three-dimensional reconstruction, and nondecalcified histologic sectioning. RESULTS: Scaffold-induced bone growth was statistically greater than bone growth in empty defects (p = 0.02). Large scaffold pores, 500 μm, coated in 1000 μM dipyridamole yielded the most bone growth and lowest degree of scaffold presence within the defect. Histology showed vascularized woven and lamellar bone along with initial formation of vascular canals within the scaffold lattice. Micro-computed tomographic and histologic analysis revealed patent calvarial sutures without evidence of ectopic bone formation across all dipyridamole concentrations. CONCLUSION: The authors present an effective pediatric bone tissue-engineering scaffold design and dipyridamole concentration that is effective in augmentation of calvarial bone generation while preserving cranial suture patency.</p>