• Ermiş, Ekin
• Anschuetz, Lukas
• Stalder, Odile
• Wagner, Franca
• Gebhart, Isabel
• Vibert, Dominique
• Mantokoudis, Georgios
• Raabe, Andreas
• Hermann, Evelyne
• Caversaccio, Marco

Abstract

<jats:sec><jats:title>Objective:</jats:title><jats:p>Evaluation at long term of the impact of the stereotactic surgery (SRS) on the vestibular function in vestibular schwannoma (VS) patients.</jats:p></jats:sec><jats:sec><jats:title>Study design and setting:</jats:title><jats:p>Retrospective study in a tertiary referral center.</jats:p></jats:sec><jats:sec><jats:title>Patients:</jats:title><jats:p>Fifty-one VS patients were included (34 females;17 males), aged from 41 to 78 years treated exclusively with SRS.</jats:p></jats:sec><jats:sec><jats:title>Intervention:</jats:title><jats:p>Vestibular function was assessed before SRS and with median time interval of 14 (FU1) and 25 (FU2) months after treatment. Vestibular evaluation included: history, clinical vestibular examination, videonystagmography, head impulse test (v-HIT) and cervical vestibular evoked myogenic potentials (c-VEMPS).</jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p>Before SRS, caloric testing (Caloric) was impaired in 77%; after treatment, in 92% (FU1) and 77% (FU2). Lateral HIT was decreased in 22% before SRS, in 39% at FU1 and FU2. C-VEMPS were absent in 50% before SRS, in 76% at FU1 and, FU2. Before SRS, no statistically significant association was found between asymptomatic and symptomatic patients with respect to the results of Caloric, v-HIT and c-VEMPS. This lack of association was also seen after SRS, at FU1 and FU2.</jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p>Our study showed that the impairment of the vestibular function might be attributed to the VS itself as well as to the radiation of the inner ear during SRS. The lateral SSC at low frequencies and the saccular function seem to be more involved with the time.</jats:p></jats:sec>

Topics

• size-exclusion chromatography