• Dalmas, Florian
• David, Thierry
• Guyot, Laurent
• Bertrand, Baptiste
• Schmid, Amaury
• Chaneac, Livia

Abstract

<jats:sec><jats:title>Purpose:</jats:title><jats:p>This study aims to evaluate the influence of preoperative phenylephrine testing on the surgical outcome of patients undergoing surgery for involutional ptosis by external levator advancement.</jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p>This was an observational, monocentric, retrospective study. Fifty-one eyelids from 32 patients, who had surgery between January 2018 and May 2023, were included for analysis. Preoperative clinical examination data were collected. Evaluation was performed at 1 month postoperatively. Surgical success was defined by a postoperative margin reflex distance between 3 and 5 mm inclusive. Symmetry success was defined by a difference in margin reflex distance between the 2 upper eyelids of no more than 1 mm.</jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p>The surgical success rate was 86%. A positive preoperative phenylephrine test was significantly associated with a better surgical success rate (<jats:italic toggle="yes">p</jats:italic> = 0.01), including on symmetry (<jats:italic toggle="yes">p</jats:italic> = 0.01). The secondary outcomes, namely preoperative margin reflex distance, function of the upper eyelid levator muscle, and unilaterality of surgery, were not statistically associated with surgical outcome.</jats:p></jats:sec><jats:sec><jats:title>Conclusions:</jats:title><jats:p>The phenylephrine test is a predictive factor of surgical success in patients undergoing external levator advancement. Our study suggests that patients with a negative phenylephrine test should be overcorrected intraoperatively.</jats:p></jats:sec>

Topics

• impedance spectroscopy
• size-exclusion chromatography