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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Medeiros, Rui
in Cooperation with on an Cooperation-Score of 37%
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Publications (6/6 displayed)
- 2019Inhibitory effect of 5-aminoimidazole-4-carbohydrazonamides derivatives against Candida spp biofilm on nanohydroxyapatite substratecitations
- 2018Relationship between clinical toxicities and ERCC1 rs3212986 and XRCC3 rs861539 polymorphisms in cervical cancer patientscitations
- 2018TP53 Arg72Pro polymorphism is associated with increased overall survival but not response to therapy in Portuguese/Caucasian patients with advanced cervical cancercitations
- 2014FASL polymorphism is associated with response to bacillus Calmette-Guerin immunotherapy in bladder cancercitations
- 2006Association of the A870G cyclin D1 gene polymorphism with genetic susceptibility to nasopharyngeal carcinomacitations
- 2003Association between CYP2E1 polymorphisms and susceptibility to prostate cancer
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article
Association between CYP2E1 polymorphisms and susceptibility to prostate cancer
Abstract
Several genetic alterations have been associated with sporadic prostate cancer (PCa). In this study, the association between Rsal and Dral polymorphisms of CYP2E1 and PCa risk was analysed in a case-control study of 227 individuals using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Regarding Dral polymorphisms, the DD genotype is over-represented in PCa cases when compared with the control group (odds ratio (OR) 2.12; 95% confidence interval (CI) 1.11-4.05; P = 0.022). Regarding the Rsal polymorphism, no significant differences were found. The results of this study indicate that Dral polymorphisms of the CYP2E1 gene may be associated with a twofold increased risk for the development of PCa. (C) 2003 Lippincott Williams Wilkins.