• Do, Dung Van
• Nguyen, Thu Anh
• Tran, Huy Hoang
• Dang, Duc Anh
• Lam, Thanh Tuan
• Marks, Guy B.
• Jan, Stephen
• Negin, Joel
• Le, Hien
• Fox, Greg J.

Abstract

<jats:title>Abstract</jats:title><jats:p>Antimicrobial resistance (AMR) is a major global issue and antimicrobial stewardship is central to tackling its emergence. The burden of AMR disproportionately impacts low- and middle-income countries (LMICs), where capacity for surveillance and management of resistant pathogens is least developed. Poorly regulated antibiotic consumption in the community is a major driver of AMR, especially in LMICs, yet community-based interventions are neglected in stewardship research, which is often undertaken in high-income settings and/or in hospitals. We reviewed the evidence available to researchers and policymakers testing or implementing community-based antimicrobial stewardship strategies in LMICs. We critically appraise that evidence, deliver recommendations and identify outstanding areas of research need. We find that multifaceted, education-focused interventions are likely most effective in our setting. We also confirm that the quality and quantity of community-based stewardship intervention research is limited, with research on microbiological, clinical and economic sustainability most urgently needed.</jats:p>

Topics

• impedance spectroscopy