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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Pelto, Jani
VTT Technical Research Centre of Finland
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (30/30 displayed)
- 2023Compatibilized PC/ABS blends from solvent recycled PC and ABS polymers from electronic equipment wastecitations
- 2021Micromechanical performance of high-density polyethylene:experimental and modeling approaches for HDPE and its alumina-nanocompositescitations
- 2021Micromechanical performance of high-density polyethylenecitations
- 2020Tribological performance of high density polyethylene (HDPE) composites with low nanofiller loadingcitations
- 2020Feasibility of Mini-Scale Injection Molding for Resource-Efficient Screening of PP-Based Cable Insulation Nanocompositescitations
- 2020Feasibility of Mini-Scale Injection Molding for Resource-Efficient Screening of PP-Based Cable Insulation Nanocompositescitations
- 2020Feasibility of Mini-Scale Injection Molding for Resource-Efficient Screening of PP-Based Cable Insulation Nanocompositescitations
- 2019Matrix morphology and the particle dispersion in HDPE nanocomposites with enhanced wear resistancecitations
- 2019Durable and light weight polymer composites for extreme wear conditions - Abrasive wear and scratch resistance of polymer composites
- 2017Application of encapsulated superabsorbent polymers in cementitious materials for stimulated autogenous healingcitations
- 2017Application of encapsulated superabsorbent polymers in cementitious materials for stimulated autogenous healingcitations
- 2017Hydrophobization and smoothing of cellulose nanofibril films by cellulose ester coatingscitations
- 2016Uniform and electrically conductive biopolymer-doped polypyrrole coating for fibrous PLAcitations
- 2016Dielectric breakdown properties of mechanically recycled SiO2-BOPP nanocompositescitations
- 2015Influence of processing on the conductive properties of PANI-EB-filled polyethylenecitations
- 2015Application of Biopolymer Doped Polypyrroles in Biomedical Implants and Electrical Stimulation Devices
- 2014Structure and dielectric breakdown strength of nano calcium carbonate/polypropylene compositescitations
- 2014Encapsulation of 3-iodo-2-propynyl N-butylcarbamate (IPBC) in polystyrene-polycaprolactone (PS/PCL) blendscitations
- 2013Novel polypyrrole-coated polylactide scaffolds enhance adipose stem cell proliferation and early osteogenic differentiationcitations
- 2013Surface properties and interaction forces of biopolymer-doped conductive polypyrrole surfaces by atomic force microscopycitations
- 2012Surface modification of nanosilica for PP composites
- 2011Surface modification of nanosilica for PP composites
- 2011Investigation of the optimal processing parameters for picosecond laser-induced microfabrication of a polymer-ceramic hybrid materialcitations
- 2010Effect of low amount of nanosilica on dielectric properties of polypropylenecitations
- 2010Dielectric properties and partial discharge endurance of polypropylene-silica nanocompositecitations
- 2008Thermal, mechanical and dielectric properties of nanostructured epoxy-polyhedral oligomeric silsesquioxane compositescitations
- 2008Surface degradation of nanostructured polypropylene compounds caused by partial dischargescitations
- 2005Development of polyester and polyamide conductive fibrecitations
- 2004Electrical properties of polypropylene and polyaniline compoundscitations
- 2004Nonlinear DC voltage-current characteristics of new polymeric composite materials based on semiconductive polyaniline emeraldine base fillercitations
Places of action
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article
Novel polypyrrole-coated polylactide scaffolds enhance adipose stem cell proliferation and early osteogenic differentiation
Abstract
An electrically conductive polypyrrole (PPy) doped with a bioactive agent is an emerging functional biomaterial for tissue engineering. We therefore used chondroitin sulfate (CS)-doped PPy coating to modify initially electrically insulating polylactide resulting in novel osteogenic scaffolds. In situ chemical oxidative polymerization was used to obtain electrically conductive PPy coating on poly-96L/4D-lactide (PLA) nonwoven scaffolds. The coated scaffolds were characterized and their electrical conductivity was evaluated in hydrolysis. The ability of the coated and conductive scaffolds to enhance proliferation and osteogenic differentiation of human adipose stem cells (hASCs) under electrical stimulation (ES) in three-dimensional (3D) geometry was compared to the noncoated PLA scaffolds. Electrical conductivity of PPy-coated PLA scaffolds (PLA-PPy) was evident at the beginning of hydrolysis, but decreased during the first week of incubation due to de-doping. PLA-PPy scaffolds enhanced hASC proliferation significantly compared to the plain PLA scaffolds at 7 and 14 days. Furthermore, the alkaline phosphatase (ALP) activity of the hASCs was generally higher in PLA-PPy seeded scaffolds, but due to patient variation, no statistical significance could be determined. ES did not have a significant effect on hASCs. This study highlights the potential of novel PPy-coated PLA scaffolds in bone tissue engineering.