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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Madsen, Frederikke Bahrt
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (39/39 displayed)
- 2024Permeation-Enhancing Strategies for Transdermal Delivery of Cannabinoidscitations
- 2023Antimicrobial silicone skin adhesives facilitated by controlled octenidine release from glycerol compartmentscitations
- 2022A reliable quantitative method for determining CBD content and release from transdermal patches in Franz cellscitations
- 2021Glycerol‐Filled Silicone Adhesive Patches with Excellent Sun Protectioncitations
- 2019Glycerol-silicone foams - Tunable 3-phase elastomeric porous materialscitations
- 2018Degradation patterns of silicone-based dielectric elastomers in electrical fieldscitations
- 2016Silicone elastomers with superior softness and dielectric properties
- 2016Bimodal condensation silicone elastomers as dielectric elastomers
- 2016Self-Healing, High-Permittivity Silicone Dielectric Elastomercitations
- 2016A simple method for reducing inevitable dielectric loss in high-permittivity dielectric elastomerscitations
- 2016The Current State of Silicone-Based Dielectric Elastomer Transducerscitations
- 2016Molecular beam deposition of high-permittivity polydimethylsiloxane for nanometer-thin elastomer films in dielectric actuatorscitations
- 2016Molecular beam deposition of high-permittivity polydimethylsiloxane for nanometer-thin elastomer films in dielectric actuatorscitations
- 2016Mechanically compliant electrodes and dielectric elastomers from PEG-PDMS copolymers
- 2016Mechanical and Electrical Ageing Effects on the Long-Term Stretching of Silicone Dielectric Elastomers with Soft Fillers:Long-Term Stretching of Silicone Dielectric Elastomerscitations
- 2015A new soft dielectric silicone elastomer matrix with high mechanical integrity and low lossescitations
- 2015Super soft silicone elastomers with high dielectric permittivitycitations
- 2015High energy density interpenetrating networks from ionic networks and siliconecitations
- 2015Dielectric elastomers, with very high dielectric permittivity, based on silicone and ionic interpenetrating networkscitations
- 2015Functional silicone elastomers via novel siloxane copolymers and chain extenders
- 2015Functional silicone copolymers and elastomers with high dielectric permittivity
- 2015Silicone chain extender
- 2015Soft Functional Silicone Elastomers with High Dielectric Permittivty: Simple Additives vs. Cross-Linked Synthesized Copolymers
- 2015Silicone elastomers with high dielectric permittivity and high dielectric breakdown strength based on tunable functionalized copolymerscitations
- 2014Synthetic Strategies for High Dielectric Constant Silicone Elastomers
- 2014Synthetic Strategies for High Dielectric Constant Silicone Elastomers
- 2014Silicone elastomers with high dielectric permittivity and high dielectric breakdown strength based on dipolar copolymerscitations
- 2013Novel silicone compatible cross-linkers for controlled functionalization of PDMS networkscitations
- 2013Novel cross-linkers for PDMS networks for controlled and well distributed grafting of functionalities by click chemistrycitations
- 2013Silicone resembling poly (propylene glycol) interpenetrating networks based on no pre-stretch as basis for electrical actuatorscitations
- 2013Dipolar cross-linkers for PDMS networks with enhanced dielectric permittivity and low dielectric losscitations
- 2013Intelligente materialer som kunstige muskler og energi-høstere
- 2013Development of novel PDMS elastomers for dielectric electroactive polymers (DEAPs)
- 2012New Cross-linkers for PDMS Networks
- 2012Development of new PDMS based materials for dielectric electroactive polymers (DEAPs) as actuators and generators
- 2012Udvikling af materialer til kunstige muskler
- 2012Novel silicone compatible cross-linkers for controlled and well distributed functionalization of PDMS networks
- 2012Bimodal Networks as Candidates for Electroactive Polymers
- 2011New Cross-linkers for PDMS Networks
Places of action
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article
Permeation-Enhancing Strategies for Transdermal Delivery of Cannabinoids
Abstract
Introduction: This review aims to provide an overview of the advancements and status of clinical studies and potential permeation-enhancing strategies in the transdermal delivery of cannabinoids. Methods: A systematic and comprehensive literature search across academic databases, search engines, and online sources to identify relevant literature on the transdermal administration of cannabinoids. Results: Cannabinoids have proven beneficial in the treatment of wide-ranging physical and psychological disorders. A shift toward legalized cannabinoid products has increased both interests in cannabinoid research and the development of novel medicinal exploitations of cannabinoids in recent years. Oral and pulmonary delivery of cannabinoids has several limitations, including poor bioavailability, low solubility, and potential side effects. This has diverted scientific attention toward the transdermal route, successfully overcoming these hurdles by providing higher bioavailability, safety, and patient compliance. Yet, due to the barrier properties of the skin and the lipophilic nature of cannabinoids, there is a need to increase the permeation of the drugs to the underneath layers of skin to reach desired therapeutic plasma levels. Literature describing detailed clinical trials on cannabinoid transdermal delivery, either with or without permeation-enhancing strategies, is limited. Conclusion: The limited number of reports indicates that increased attention is needed on developing and examining efficient transdermal delivery systems for cannabinoids, including patch design and composition, drug-patch interaction, clinical effectiveness and safety in vivo, and permeation-enhancing strategies.