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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Khademhosseini, Ali
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (12/12 displayed)
- 2023A handheld bioprinter for multi-material printing of complex constructscitations
- 2023Aerogel-Based Biomaterials for Biomedical Applications: From Fabrication Methods to Disease-Targeting Applicationscitations
- 2023Drug‐Eluting Shear‐Thinning Hydrogel for the Delivery of Chemo‐ and Immunotherapeutic Agents for the Treatment of Hepatocellular Carcinomacitations
- 2022Assessing the aneurysm occlusion efficacy of a shear-thinning biomaterial in a 3D-printed model.citations
- 2022Additively manufactured metallic biomaterialscitations
- 2021In situ 3D printing of implantable energy storage devicescitations
- 2019The future of layer-by-layer assembly: A tribute to ACS Nano associate editor Helmuth Möhwaldcitations
- 2019Biocompatible Carbon Nanotube-Based Hybrid Microfiber for Implantable Electrochemical Actuator and Flexible Electronic Applications.citations
- 2018Nanobead-on-string composites for tendon tissue engineeringcitations
- 2017Biodegradable elastic nanofibrous platforms with integrated flexible heaters for on-demand drug deliverycitations
- 2016Nanotechnology in textilescitations
- 2016Platinum nanopetal-based potassium sensors for acute cell death monitoringcitations
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article
A handheld bioprinter for multi-material printing of complex constructs
Abstract
<jats:title>Abstract</jats:title><jats:p>In situ bioprinting, also known as the process of depositing bioinks at the defect site, has emerged as a promising strategy for the repair and restoration of large tissues. This technology accomplishes these goals through the site-specific delivery of pro-healing structures. However, realising the full potential of this technology requires the ability to print multiple materials for simultaneous or sequential dispensing of a variety of drugs and cells for better tissue biomimicry. In this article, we describe a portable and modular bioprinter that is capable of depositing a variety of bioinks while allowing for precise control over their physicochemical properties. Using stereolithography (SLA) 3D printing, we construct microfluidic printheads with complex fluid circuitries that allow for the deposition of multi-component fibers with sophisticated cross-sectional geometries and material compositions. In addition, the modular design of this platform makes it possible to print a wide variety of bioinks, such as those that can be chemically or photo-crosslinked, as well as nano-composite inks with shear-thinning and self-healing properties. The versatility of this technology for biomedical applications is demonstrated by printing constructs for co-delivery of various drugs or cells at the same time, as well as generating implanted biosensors. Overall, this method not only has a significant potential for site-specific and in situ tissue printing, but it also has the potential to have applications in traditional ex vivo bioprinting for automated and high throughput tissue engineering.</jats:p>