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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Irfan, Muhammad
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (16/16 displayed)
- 2024Oxidized alginate-gelatin (ADA-GEL)/silk fibroin/Cu-Ag doped mesoporous bioactive glass nanoparticle-based hydrogels for potential wound care treatmentscitations
- 2024Utilization of NiO-rGO Nanoarchitectures-Based Composite Electrodes for High-Performance Electrochemical Applications
- 2023Harnessing the Antimicrobial Potential of Natural Starch and Mint Extract in PVA-Based Biodegradable films against Staphylococcus aureus bacteriacitations
- 2023Indoor water splitting for hydrogen production through electrocatalysis using composite metal oxide catalystscitations
- 2023Microencapsulation based fire retardant eco-friendly jute compositecitations
- 2023Temperature-Properties Relationships of Martensitic Stainless Steel for Improved Utilization in Surgical Tools
- 2022Zn–Mn-Doped Mesoporous Bioactive Glass Nanoparticle-Loaded Zein Coatings for Bioactive and Antibacterial Orthopedic Implantscitations
- 2022Assessing the Synergistic Activity of Clarithromycin and Therapeutic Oils Encapsulated in Sodium Alginate Based Floating Microbeadscitations
- 2022Electrospun Networks of ZnO-SnO2 Composite Nanowires as Electron Transport Materials for Perovskite Solar Cellscitations
- 2021Poloxamer-188 and d-α-Tocopheryl Polyethylene Glycol Succinate (TPGS-1000) Mixed Micelles Integrated Orodispersible Sublingual Films to Improve Oral Bioavailability of Ebastine; In Vitro and In Vivo Characterizationcitations
- 2021<i>Moringa oleifera</i> gum based silver and zinc oxide nanoparticles: green synthesis, characterization and their antibacterial potential against MRSAcitations
- 2018Comparative Experimental Study of Tribo-Mechanical Performance of Low-Temperature PVD Based TiN Coated PRCL Systems for Diesel Enginecitations
- 2018Fast photocatalytic degradation of dyes using low-power laser-fabricated Cu2O–Cu nanocompositescitations
- 2017Characterization of antibacterial silver nanocluster/silica composite coating on high performance Kevlar® textilecitations
- 2015Bisphenol A based polyester binder as an effective interlaminar toughenercitations
- 2012Lateral spreading of a fiber bundle via mechanical meanscitations
Places of action
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article
Oxidized alginate-gelatin (ADA-GEL)/silk fibroin/Cu-Ag doped mesoporous bioactive glass nanoparticle-based hydrogels for potential wound care treatments
Abstract
<jats:title>Abstract</jats:title><jats:p>The present work focuses on developing 5% w/v oxidized alginate (alginate di aldehyde, ADA)-7.5% w/v gelatin (GEL) hydrogels incorporating 0.25% w/v silk fibroin (SF) and loaded with 0.3% w/v Cu-Ag doped mesoporous bioactive glass nanoparticles (Cu-Ag MBGNs). The microstructural, mechanical, and biological properties of the composite hydrogels were characterized in detail. The porous microstructure of the developed ADA-GEL based hydrogels was confirmed by scanning electron microscopy, while the presence of Cu-Ag MBGNs in the synthesized hydrogels was determined using energy dispersive x-ray spectroscopy. The incorporation of 0.3% w/v Cu-Ag MBGNs reduced the mechanical properties of the synthesized hydrogels, as investigated using micro-tensile testing. The synthesized ADA-GEL loaded with 0.25% w/v SF and 0.3% w/v Cu-Ag MBGNs showed a potent antibacterial effect against <jats:italic>Escherichia coli</jats:italic> and <jats:italic>Staphylococcus aureus</jats:italic>. Cellular studies using the NIH3T3-E1 fibroblast cell line confirmed that ADA-GEL films incorporated with 0.3% w/v Cu-Ag MBGNs exhibited promising cellular viability as compared to pure ADA-GEL (determined by WST-8 assay). The addition of SF improved the biocompatibility, degradation rate, moisturizing effects, and stretchability of the developed hydrogels, as determined <jats:italic>in vitro</jats:italic>. Such multimaterial hydrogels can stimulate angiogenesis and exhibit desirable antibacterial properties. Therefore further (<jats:italic>in vivo</jats:italic>) tests are justified to assess the hydrogels’ potential for wound dressing and skin tissue healing applications.</jats:p>