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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Dubruel, Peter
Ghent University
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (31/31 displayed)
- 2024Tailorable acrylate-endcapped urethane-based polymers for precision in digital light processing : versatile solutions for biomedical applicationscitations
- 2023Polymeric reinforcements for cellularized collagen-based vascular wall models: influence of the scaffold architecture on the mechanical and biological propertiescitations
- 2023Printability evaluation of UV-curable aqueous laponite/urethane-based PEG inkscitations
- 2023Solid‐state crosslinkable, shape‐memory polyesters serving tissue engineeringcitations
- 2023Microstructured Optical Fiber Made From Biodegradable and Biocompatible Poly(D,L-Lactic Acid) (PDLLA)citations
- 2021Increasing the Microfabrication Performance of Synthetic Hydrogel Precursors through Molecular Designcitations
- 2021Capacitive sensing of an amphetamine drug precursor in aqueous samples : application of novel molecularly imprinted polymers for benzyl methyl ketone detectioncitations
- 2021Capacitive sensing of an amphetamine drug precursor in aqueous samples : application of novel molecularly imprinted polymers for benzyl methyl ketone detectioncitations
- 2021Increasing the microfabrication performance of synthetic hydrogel precursors through molecular designcitations
- 2020On the Characterization of Novel Step-Index Biocompatible and Biodegradable poly(D,L-lactic acid) Based Optical Fibercitations
- 2019Amorphous random copolymers of lacOCA and manOCA for the design of biodegradable polyesters with tuneable propertiescitations
- 2019Amorphous random copolymers of lacOCA and manOCA for the design of biodegradable polyesters with tuneable propertiescitations
- 2018Clear to clear laser welding for joining thermoplastic polymers: A comparative study based on physicochemical characterizationcitations
- 2018Ultrathin Poly-DL-Lactic Membranes for Corneal Endothelial Transplantation
- 2018Localized optical- quality doping of graphene on silicon waveguides through a TFSA- containing polymer matrixcitations
- 2018Ring opening copolymerisation of lactide and mandelide for the development of environmentally degradable polyesters with controllable glass transition temperaturescitations
- 2017Combinatory approach of methacrylated alginate and acid monomers for concrete applicationscitations
- 2017Characterization of methacrylated polysaccharides in combination with amine-based monomers for application in mortarcitations
- 2016Indirect solid freeform fabrication of an initiator-free photocrosslinkable hydrogel precursor for the creation of porous scaffoldscitations
- 2016Deep proton writing with 12 MeV protons for rapid prototyping of microstructures in polymethylmethacrylatecitations
- 2016Chapter 21 – Biodegradable polyesters: from monomer to application
- 2015Autogenous healing of cementitious materials promoted by superabsorbent polymers studied by means of X-ray computed microtomography
- 2014Direct synthesis and morphological characterization of gold-dendrimer nanocomposites prepared using PAMAM succinamic acid dendrimers: preliminary study of the calcification potential
- 2013Magnesium-enhanced enzymatically mineralized platelet-rich fibrin for bone regeneration applicationscitations
- 2012Implantable (bio)polymer coated titanium scaffolds : a reviewcitations
- 2011Gelatin functionalization of biomaterial surfaces : strategies for immobilization and visualizationcitations
- 2011Photonic crystal fiber Bragg grating based sensors: opportunities for applications in healthcarecitations
- 2011Surface modification of a photo definable epoxy resin with polydopamine to improve adhesion with electroless deposited copper
- 2011Surface modification of a photo definable epoxy resin with polydopamine to improve adhesion with electroless deposited copper
- 2011Photonic crystal fiber Bragg grating based sensorscitations
- 2008Flexible materials for optical applications
Places of action
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article
Magnesium-enhanced enzymatically mineralized platelet-rich fibrin for bone regeneration applications
Abstract
Membranes of the autologous blood-derived biomaterial platelet-rich fibrin (PRF) were mineralized enzymatically with calcium phosphate (CaP) by the incorporation of alkaline phosphatase (ALP) followed by incubation for 3 days in solutions of either 0.1 M calcium glycerophosphate (CaGP) or a combination of CaGP and magnesium glycerophosphate (CaGP:MgGP; both 0.05 M), resulting in the formation of two different PRF-mineral composites. Fourier transform infrared spectroscopy, transmission electron microscopy and selected area electron diffraction examinations showed that the CaP formed was amorphous. Inductively coupled plasma optical emission spectroscopy analysis revealed similar amounts of Ca and P in both composite types, while a smaller amount of Mg (Ca:Mg molar ratio = 10) was detected in the composites formed in the CaGP:MgGP solution, which was supported by the results of energy-dispersive x-ray spectroscopy-based elemental mapping. Scanning electron microscopy (SEM) imaging showed that the mineral deposits in PRF incubated in the CaGP:MgGP solution were markedly smaller. The mass percentage attributable to the mineral phase was similar in both composite types. MTT and WST tests with SAOS-2 cells revealed that incubation in the CaGP:MgGP solution had no negative effect on cytocompatibility and cell proliferation compared to the CaGP solution. Cells on all samples displayed a well-spread morphology as revealed by SEM imaging. In conclusion, the incorporation of Mg reduces mineral deposit dimensions and promotes cell proliferation.