| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Wolff, Anders
Technical University of Denmark
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (14/14 displayed)
- 2019Fabrication of 3D microstructure array on chip for rapid pathogen detectioncitations
- 2019Large-scale fabrication of microfluidic chips with three-dimensional microstructures for point of care application
- 2019Large-scale fabrication of microfluidic chips with three-dimensional microstructures for point of care application
- 2019A Complete Protocol for Rapid and Low-Cost Fabrication of Polymer Microfluidic Chips Containing Three-Dimensional Microstructures Used in Point-of-Care Devicescitations
- 2016Laser ablated micropillar energy directors for ultrasonic welding of microfluidic systemscitations
- 2016MICRO-SCALE ENERGY DIRECTORS FOR ULTRASONIC WELDING
- 2015Ultrasonic welding for fast bonding of self-aligned structures in lab-on-a-chip systemscitations
- 2014Fabrication and modelling of injection moulded all-polymer capillary microvalves for passive microfluidic controlcitations
- 2012A novel detection platform for parallel monitoring of DNA hybridization with high sensitivity and specificity
- 2012A novel detection platform for parallel monitoring of DNA hybridization with high sensitivity and specificity
- 2010Microfluidic DNA microarrays in PMMA chips: streamlined fabrication via simultaneous DNA immobilization and bonding activation by brief UV exposurecitations
- 2007PCR biocompatibility of Lab-on-a-chip and MEMS materialscitations
- 2006Dielectrophoresis microsystem with integrated flow cytometers for on-line monitoring of sorting efficiencycitations
- 2004Numerical simulation of travelling wave induced electrothermal fluid flowcitations
Places of action
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article
Fabrication and modelling of injection moulded all-polymer capillary microvalves for passive microfluidic control
Abstract
Rapid prototyping is desirable when developing products. One example of such a product is all-polymer, passive flow controlled lab-on-a-chip systems that are preferential when developing low-cost disposable chips for point-of-care use. In this paper we investigate the following aspects of going from rapid prototyping to pilot (mass) production. (1) Fabrication of an all-polymer microfluidic system using a rapid prototyped master insert for injection moulding and ultrasonic welding, including a systematic experimental characterisation of chip featured geometric capillary microvalve test structures. (2) Numerical modelling of the microvalve burst pressures. Numerical modelling of burst pressures is challenging due to its non-equilibrium nature. We have implemented and tested the level-set method modified with a damped driving term and show that the introduction of the damping term leads to numerically robust results with limited computational demands and a low number of iterations. Numerical and simplified analytical results are validated against the experimental results. We find that injection moulding and ultrasonic welding are effective for chip production and that the experimental burst pressures could be estimated with an average accuracy of 5% using the presented numerical model.