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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Sack, I.
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (23/23 displayed)
- 2024On the relationship between viscoelasticity and water diffusion in soft biological tissues.citations
- 2022Mechanical behavior of the hippocampus and corpus callosum: An attempt to reconcile ex vivo with in vivo and micro with macro properties.citations
- 2021Real-Time Multifrequency MR Elastography of the Human Brain Reveals Rapid Changes in Viscoelasticity in Response to the Valsalva Maneuver.citations
- 2020Cardiac-gated steady-state multifrequency magnetic resonance elastography of the brain: Effect of cerebral arterial pulsation on brain viscoelasticity.citations
- 2019Sensitivity of multifrequency magnetic resonance elastography and diffusion-weighted imaging to cellular and stromal integrity of liver tissue.citations
- 2018Combining viscoelasticity, diffusivity and volume of the hippocampus for the diagnosis of Alzheimer's disease based on magnetic resonance imaging.citations
- 2015Tabletop magnetic resonance elastography for the measurement of viscoelastic parameters of small tissue samples.citations
- 2014High-resolution mechanical imaging of the kidney.citations
- 2014Wideband MRE and static mechanical indentation of human liver specimen: sensitivity of viscoelastic constants to the alteration of tissue structure in hepatic fibrosis.citations
- 2014In vivo time-harmonic multifrequency elastography of the human liver.citations
- 2013Compression-sensitive magnetic resonance elastography.citations
- 2013Isovolumetric elasticity alteration in the human heart detected by in vivo time-harmonic elastography.citations
- 2012Fractal network dimension and viscoelastic powerlaw behavior: I. A modeling approach based on a coarse-graining procedure combined with shear oscillatory rheometry.citations
- 2010Viscoelasticity-based MR elastography of skeletal muscle.citations
- 2010Viscoelasticity-based staging of hepatic fibrosis with multifrequency MR elastography.citations
- 2010Viscoelastic properties of liver measured by oscillatory rheometry and multifrequency magnetic resonance elastography.citations
- 2008Non-invasive measurement of brain viscoelasticity using magnetic resonance elastography.citations
- 2008Assessment of liver viscoelasticity using multifrequency MR elastography.citations
- 2007Three-dimensional analysis of shear wave propagation observed by in vivo magnetic resonance elastography of the brain.citations
- 2007Noninvasive assessment of the rheological behavior of human organs using multifrequency MR elastography: a study of brain and liver viscoelasticity.citations
- 2006Shear wave group velocity inversion in MR elastography of human skeletal muscle.citations
- 2003Electromagnetic actuator for generating variably oriented shear waves in MR elastography.citations
- 2002Analysis of wave patterns in MR elastography of skeletal muscle using coupled harmonic oscillator simulations.
Places of action
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article
Noninvasive assessment of the rheological behavior of human organs using multifrequency MR elastography: a study of brain and liver viscoelasticity.
Abstract
MR elastography (MRE) enables the noninvasive determination of the viscoelastic behavior of human internal organs based on their response to oscillatory shear stress. An experiment was developed that combines multifrequency shear wave actuation with broad-band motion sensitization to extend the dynamic range of a single MRE examination. With this strategy, multiple wave images corresponding to different driving frequencies are simultaneously received and can be analyzed by evaluating the dispersion of the complex modulus over frequency. The technique was applied on the brain and liver of five healthy volunteers. Its repeatability was tested by four follow-up studies in each volunteer. Five standard rheological models (Maxwell, Voigt, Zener, Jeffreys and fractional Zener model) were assessed for their ability to reproduce the observed dispersion curves. The three-parameter Zener model was found to yield the most consistent results with two shear moduli mu(1) = 0.84 +/- 0.22 (1.36 +/- 0.31) kPa, mu(2) = 2.03 +/- 0.19 (1.86 +/- 0.34) kPa and one shear viscosity of eta = 6.7 +/- 1.3 (5.5 +/- 1.6) Pa s (interindividual mean +/- SD) in brain (liver) experiments. Significant differences between the rheological parameters of brain and liver were found for mu(1) and eta (P < 0.05), indicating that human brain is softer and possesses a higher viscosity than liver.