| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Gibson, Ian
University of Twente
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (40/40 displayed)
- 2023Impact of powder reusability on batch repeatability of Ti6Al4V ELI for PBF-LB industrial productioncitations
- 2023Estimating minimum required dwell time for the heat sealing of talc containing polypropylene/low‐density polyethylene packaging filmscitations
- 2023Effects of film tension and contamination on the seal quality of flexible food packaging films made of polypropylene and low density polyethylene blends containing talc fillercitations
- 2023Heat treatment for metal additive manufacturingcitations
- 2023Towards more homogeneous character in 3D printed photopolymers by the addition of nanofillerscitations
- 2022Sandwich structure printing of Ti-Ni-Ti by directed energy depositioncitations
- 2021Build position-based dimensional deviations of laser powder-bed fusion of stainless steel 316Lcitations
- 2021A critical review of corrosion characteristics of additively manufactured stainless steelscitations
- 2021On the role of process parameters on meltpool temperature and tensile properties of stainless steel 316L produced by powder bed fusioncitations
- 2020Porous materials additively manufactured at low energycitations
- 2020Modelling of laser powder bed fusion process and analysing the effective parameters on surface characteristics of Ti-6Al-4Vcitations
- 2020Corrosion behaviour of additively manufactured 316L stainless steel
- 2020A review of technological improvements in laser-based powder bed fusion of metal printerscitations
- 2020The effect of process parameters and mechanical properties of direct energy deposited stainless steel 316
- 2020On the role of wet abrasive centrifugal barrel finishing on surface enhancement and material removal rate of LPBF stainless steel 316Lcitations
- 2020Pulsed mode selective laser melting of porous structures: Structural and thermophysical characterizationcitations
- 2019Unexpected erosion-corrosion behaviour of 316L stainless steel produced by selective laser meltingcitations
- 2019Investigation on the effect of heat treatment and process parameters on the tensile behaviour of SLM Ti-6Al-4V partscitations
- 2019An Overview: Laser-Based Additive Manufacturing for High Temperature Tribologycitations
- 2019Melt Pool Monitoring for the Laser Powder Bed Fusion Process
- 2019On the unusual intergranular corrosion resistance of 316L stainless steel additively manufactured by selective laser meltingcitations
- 2019Directed energy deposition and characterization of high-carbon high speed steelscitations
- 2019A comprehensive study on variability of relative density in selective laser melting of Ti-6Al-4Vcitations
- 2018Mass transfer and flow in additive manufacturing of a spherical componentcitations
- 2018Accelerating Experimental Design by Incorporating Experimenter Hunchescitations
- 2018A comprehensive study on surface quality in 5-axis milling of SLM Ti-6Al-4V spherical componentscitations
- 2018Characterizing the effect of cutting condition, tool path, and heat treatment on cutting forces of selective laser melting spherical component in five-axis millingcitations
- 2018Investigation on the effect of a pre-center drill hole and tool material on thrust force, surface roughness, and cylindricity in the drilling of Al7075citations
- 2018Rheological characterization of process parameters influence on surface quality of Ti-6Al-4V parts manufactured by selective laser meltingcitations
- 2017Production of Ti-6Al-4V acetabular shell using selective laser meltingcitations
- 2017The Effect of Vibration during Friction Stir Welding on Corrosion Behavior, Mechanical Properties, and Machining Characteristics of Stir Zonecitations
- 2017Improving EDM Process on AZ31 Magnesium Alloy towards Sustainable Biodegradable Implant Manufacturingcitations
- 2017On the role of different annealing heat treatments on mechanical properties and microstructure of selective laser melted and conventional wrought Ti-6Al-4Vcitations
- 2016An improved static model for tool deflection in machining of Ti–6Al–4V acetabular shell produced by selective laser meltingcitations
- 2016A survey on mechanisms and critical parameters on solidification of selective laser melting during fabrication of Ti-6Al-4V prosthetic acetabular cupcitations
- 2013Process and material behavior modeling for a new design of micro-additive fused depositioncitations
- 2013Process and material behavior modeling for a new design of micro-additive fused depositioncitations
- 2010The future of electronic products
- 2009Composite PLDLLA/TCP Scaffolds for Bone Engineeringcitations
- 2008Mechanical and in vitro evaluations of composite PLDLLA/TCP scaffolds for bone engineeringcitations
Places of action
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article
Mechanical and in vitro evaluations of composite PLDLLA/TCP scaffolds for bone engineering
Abstract
<p>Bone tissue engineering scaffolds have two challenging functional tasks to play; to be bioactive by encouraging cell proliferation and differentiation, and to provide suitable mechanical stability upon implantation. Composites of biopolymers and bioceramics unite the advantages of both materials, resulting in better processability, enhanced mechanical properties through matrix reinforcement and osteoinductivity. Novel composite blends of poly(L-lactide-co-D,L-lactide)/tricalcium phosphate (PLDLLA/TCP) were fabricated into scaffolds by an extrusion deposition technique customised from standard rapid prototyping technology. PLDLLA/TCP composite material blends of various compositions were prepared and analysed for their mechanical properties. PLDLLA/TCP (10%) was optimised and fabricated into scaffolds. Compressive mechanical properties for the composite scaffolds were measured. In vitro studies were conducted using porcine bone-marrow stromal cells (BMSCs). Cell-scaffold constructs were induced using osteogenic induction factors for up to 8 weeks. Cell proliferation, viability and differentiation capabilities were assayed using phase-contrast light microscopy, scanning electron microscopy, DNA quantification (Pico Green), Alamar Blue metabolic assay; FDA/PI fluorescent assay and western blot analysis for osteopontin. Microscopy observations showed BMSCs possessed high proliferative capabilities and demonstrated bridging across the pores of the scaffolds. FDA/PI staining as well as Alamar Blue assay showed high viability of BMSCs cultured on the composite scaffolds. Cell numbers, based on DNA quantitation, were observed to increase continuously up to the eighth week of study. Western blot analysis showed increased osteopontin synthesis on the scaffolds compared to tissue culture plastic. Based on our results the PLDLLA/TCP scaffolds exhibited good potential and biocompatibility for bone tissue engineering applications.</p>