Materials Map

Discover the materials research landscape. Find experts, partners, networks.

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The Materials Map is an open tool for improving networking and interdisciplinary exchange within materials research. It enables cross-database search for cooperation and network partners and discovering of the research landscape.

The dashboard provides detailed information about the selected scientist, e.g. publications. The dashboard can be filtered and shows the relationship to co-authors in different diagrams. In addition, a link is provided to find contact information.

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Materials Map under construction

The Materials Map is still under development. In its current state, it is only based on one single data source and, thus, incomplete and contains duplicates. We are working on incorporating new open data sources like ORCID to improve the quality and the timeliness of our data. We will update Materials Map as soon as possible and kindly ask for your patience.

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693.932 PEOPLE
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Naji, M.
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Liu, M.

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in Cooperation with on an Cooperation-Score of 37%

Topics

Publications (12/12 displayed)

  • 2025Surface Modified CsPbBr3 Nanocrystals Enable Free Radical Thermal Polymerization of Efficient Ultrafast Polystirenic Nanocomposite Scintillators1citations
  • 2024Halide Engineering in Mixed Halide Perovskite-Inspired Cu2AgBiI6 for Solar Cells with Enhanced Performance4citations
  • 2023Corrosion and passive film characteristics of 3D-printed NiTi shape memory alloys in artificial saliva23citations
  • 2023Passive film formation and corrosion resistance of laser-powder bed fusion fabricated NiTi shape memory alloys38citations
  • 2021Positron annihilation investigation of thermal cycling induced martensitic transformation in NiTi shape memory alloy8citations
  • 2021The influence of zinc electrode substrate, electrolyte flow rate and current density on zinc-nickel flow cell performance12citations
  • 2020Improving solubility and oral bioavailability of a novel antimalarial prodrug: comparing spray-dried dispersions with self-emulsifying drug delivery systems.23citations
  • 2019Fluoride-Salt-Cooled High-Temperature Reactor (FHR) Using British Advanced Gas-Cooled Reactor (AGR) Refueling Technology and Decay Heat Removal Systems That Prevent Salt Freezingcitations
  • 2019Characterization of native oxide and passive film on austenite/ferrite phases of duplex stainless steel using synchrotron haxpeem27citations
  • 2016Efficient planar heterojunction perovskite solar cells by vapour deposition.7369citations
  • 2016Efficient planar heterojunction perovskite solar cells by vapour deposition7369citations
  • 2015Charge selective contacts, mobile ions and anomalous hysteresis in organic-inorganic perovskite solar cells385citations

Places of action

Chart of shared publication
Di Sarcina, I.
1 / 3 shared
Infante, I.
1 / 6 shared
Erroi, A.
1 / 5 shared
L., Zaffalon M.
1 / 3 shared
Li, L.
1 / 90 shared
Lazzarini, L.
1 / 11 shared
Pascazio, R.
1 / 1 shared
Cemmi, A.
1 / 10 shared
Catalano, F.
1 / 2 shared
Carulli, F.
1 / 7 shared
El Adel, A.
1 / 1 shared
Bruni, F.
1 / 3 shared
Brovelli, S.
1 / 12 shared
Rossi, F.
1 / 25 shared
E., Manno D.
1 / 1 shared
Pecoraro, A.
1 / 2 shared
Ali-Loytty, H.
1 / 2 shared
K., Grandhi G.
1 / 2 shared
-P., Ruoko T.
1 / 1 shared
K., Das T.
1 / 2 shared
Manna, D.
1 / 1 shared
Pavone, M.
1 / 5 shared
Vivo, P.
1 / 3 shared
B., Munoz-Garcia A.
1 / 3 shared
Sugathan, V.
1 / 2 shared
Lahtonen, K.
1 / 7 shared
Gonzalez Garcia, Y.
2 / 16 shared
Zhu, Jia-Ning
2 / 10 shared
Popovich, V.
2 / 29 shared
Borisov, E.
2 / 4 shared
Mol, J. M. C.
2 / 93 shared
Manzoni, Anna Maria
1 / 13 shared
Banhart, J.
1 / 28 shared
Ramamurty, U.
1 / 12 shared
Diercks, P.
1 / 2 shared
Čížek, J.
1 / 20 shared
Trudgeon, Dp
1 / 1 shared
Brandon, N.
1 / 4 shared
Kong, L.
1 / 2 shared
Ullah, H.
1 / 33 shared
Yufit, V.
1 / 10 shared
Li, X.
1 / 71 shared
Loh, A.
1 / 1 shared
Green, C.
1 / 6 shared
Mk, Riscoe
1 / 1 shared
Winter, R.
1 / 2 shared
Pou, S.
1 / 1 shared
Shankar, G.
1 / 4 shared
Nilsen, A.
1 / 1 shared
Sk, Mutyam
1 / 1 shared
Potharaju, S.
1 / 1 shared
Frueh, Lisa
1 / 1 shared
Shwageraus, E.
1 / 2 shared
Mays, B.
1 / 1 shared
Parks, G.
1 / 1 shared
Forsberg, C.
1 / 1 shared
Wang, D.
1 / 42 shared
Coyle, C.
1 / 2 shared
Wiemann, Carsten
1 / 7 shared
Lundgren, Edvin
1 / 50 shared
Långberg, M.
1 / 1 shared
Lindell, D.
1 / 2 shared
Kivisäkk, U.
1 / 2 shared
Stierle, A.
1 / 9 shared
Gloskovskii, A.
1 / 15 shared
Örnek, C.
1 / 4 shared
Pan, Jinshan
1 / 37 shared
Zhang, F.
1 / 30 shared
Cheng, Jie
1 / 3 shared
Grånäs, E.
1 / 1 shared
Noei, H.
1 / 11 shared
Kulkarni, Satishkumar
1 / 7 shared
Keller, T. F.
1 / 1 shared
Matveyev, Y.
1 / 1 shared
Snaith, H.
2 / 62 shared
Johnston, M.
2 / 30 shared
Lin, H.
1 / 9 shared
C., Leijtens T.
1 / 1 shared
Zhang, W.
1 / 58 shared
Saliba, M.
1 / 10 shared
E., Eperon G.
1 / 1 shared
J., Snaith H.
1 / 4 shared
B., Johnston M.
1 / 1 shared
Mcmeekin, D.
1 / 4 shared
De Bastiani, M.
1 / 21 shared
M., Herz L.
1 / 1 shared
Zhang, Y.
1 / 149 shared
Petrozza, A.
1 / 23 shared
Chart of publication period
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2024
2023
2021
2020
2019
2016
2015

Co-Authors (by relevance)

  • Di Sarcina, I.
  • Infante, I.
  • Erroi, A.
  • L., Zaffalon M.
  • Li, L.
  • Lazzarini, L.
  • Pascazio, R.
  • Cemmi, A.
  • Catalano, F.
  • Carulli, F.
  • El Adel, A.
  • Bruni, F.
  • Brovelli, S.
  • Rossi, F.
  • E., Manno D.
  • Pecoraro, A.
  • Ali-Loytty, H.
  • K., Grandhi G.
  • -P., Ruoko T.
  • K., Das T.
  • Manna, D.
  • Pavone, M.
  • Vivo, P.
  • B., Munoz-Garcia A.
  • Sugathan, V.
  • Lahtonen, K.
  • Gonzalez Garcia, Y.
  • Zhu, Jia-Ning
  • Popovich, V.
  • Borisov, E.
  • Mol, J. M. C.
  • Manzoni, Anna Maria
  • Banhart, J.
  • Ramamurty, U.
  • Diercks, P.
  • Čížek, J.
  • Trudgeon, Dp
  • Brandon, N.
  • Kong, L.
  • Ullah, H.
  • Yufit, V.
  • Li, X.
  • Loh, A.
  • Green, C.
  • Mk, Riscoe
  • Winter, R.
  • Pou, S.
  • Shankar, G.
  • Nilsen, A.
  • Sk, Mutyam
  • Potharaju, S.
  • Frueh, Lisa
  • Shwageraus, E.
  • Mays, B.
  • Parks, G.
  • Forsberg, C.
  • Wang, D.
  • Coyle, C.
  • Wiemann, Carsten
  • Lundgren, Edvin
  • Långberg, M.
  • Lindell, D.
  • Kivisäkk, U.
  • Stierle, A.
  • Gloskovskii, A.
  • Örnek, C.
  • Pan, Jinshan
  • Zhang, F.
  • Cheng, Jie
  • Grånäs, E.
  • Noei, H.
  • Kulkarni, Satishkumar
  • Keller, T. F.
  • Matveyev, Y.
  • Snaith, H.
  • Johnston, M.
  • Lin, H.
  • C., Leijtens T.
  • Zhang, W.
  • Saliba, M.
  • E., Eperon G.
  • J., Snaith H.
  • B., Johnston M.
  • Mcmeekin, D.
  • De Bastiani, M.
  • M., Herz L.
  • Zhang, Y.
  • Petrozza, A.
OrganizationsLocationPeople

article

Improving solubility and oral bioavailability of a novel antimalarial prodrug: comparing spray-dried dispersions with self-emulsifying drug delivery systems.

  • Green, C.
  • Mk, Riscoe
  • Winter, R.
  • Pou, S.
  • Shankar, G.
  • Nilsen, A.
  • Sk, Mutyam
  • Liu, M.
  • Potharaju, S.
  • Frueh, Lisa
Abstract

To improve the solubility and oral bioavailability of a novel antimalarial agent ELQ-331(a prodrug of ELQ-300), spray-dried dispersions (SDD) and a self-emulsifying drug delivery system (SEDDS) were developed. SDD were prepared with polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer (Soluplus<sup>®</sup>) polymer carrier and Aeroperl<sup>®</sup> 300 Pharma and characterized by differential scanning calorimetry, powder X-ray diffraction. For SEDDS, solubility in oils, surfactants, and co-surfactants was determined and ternary phase diagram was constructed to show self-emulsifying area. SEDDS were characterized for spontaneous emulsification and droplet size distribution. The amorphous ELQ-331 SDD improved the solubility to 10× in fast-state simulated intestinal fluid and addition of sodium lauryl sulphate externally to SDDs further improved the solubility to ∼28.5× versus non-formulated drug. SEDDS had good self-emulsifying characteristics with small emulsion droplet sizes and narrow particle distribution. Oral pharmacokinetic studies for SDD and SEDDS formulations were performed in rats. The ELQ-331 rapidly converted to ELQ-300 soon after oral administration in rats. Exposure levels of ELQ-300 were about 1.4-fold higher (based on AUC) in SEDDS than SDD formulations. Poorly soluble drugs like ELQ-331 can be formulated using SDD or SEDDS to improve solubility and oral bioavailability.

Topics
  • dispersion
  • amorphous
  • phase
  • Sodium
  • powder X-ray diffraction
  • differential scanning calorimetry
  • copolymer
  • phase diagram
  • particle distribution
  • surfactant