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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Vilková, Mária
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article
Synthesis, solution stability, and structural characterization of quinolinol-based silver(I) complexes
Abstract
Three silver(I) complex compounds of halogen derivatives of 8-quinolinol (XQ), [Ag(HdClQ)(2)](NO3)·CH3OH (1), [Ag(HdBrQ)(2)](NO3) (2), and [Ag(BrQ)](n) (3) (HdClQ = 5,7-dichloro-8-quinolinol, HdBrQ = 5,7-dibromo-8-quinolinol, and HBrQ = 7-bromo-8-quinolinol), have been prepared with the aim to study their anticancer properties. All compounds were characterized by IR and NMR spectroscopy and elemental analysis. Single-crystal X-ray diffraction analysis revealed that crystal structure of 1 is ionic, 2 is molecular while 3 is polymeric. All three XQ ligands in 1-3 are N,O-chelate coordinated to the Ag(I) central atoms which are in a deformed square planar (1), distorted tetragonal pyramidal (2), or distorted triangular arrangement (3). Stability of all compounds in DMSO was proved by (1)H NMR and UV-vis spectroscopy. Biological activity has not been studied because of limited solubility of prepared compounds in DMSO/water mixture.