| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Rossi, Antonio
National Enterprise for NanoScience and NanoTechnology
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (11/11 displayed)
- 2024Decoupled High‐Mobility Graphene on Cu(111)/Sapphire via Chemical Vapor Depositioncitations
- 2020Production and processing of graphene and related materials
- 2020Production and processing of graphene and related materialscitations
- 2020Production and processing of graphene and related materialscitations
- 2020Production and processing of graphene and related materialscitations
- 2020Production and processing of graphene and related materialscitations
- 2020Production and processing of graphene and related materialscitations
- 2020Production and processing of graphene and related materialscitations
- 2020Production and processing of graphene and related materialscitations
- 2020Production and processing of graphene and related materials
- 2017Human NF-κB repressing factor acts as a stress-regulated switch for ribosomal RNA processing and nucleolar homeostasis surveillancecitations
Places of action
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article
Human NF-κB repressing factor acts as a stress-regulated switch for ribosomal RNA processing and nucleolar homeostasis surveillance
Abstract
<jats:title>Significance</jats:title><jats:p>Quality control of ribosomal RNA (rRNA) processing is critical for ribosome biogenesis, nucleolar homeostasis, and cell survival; however, the molecular mechanisms governing rRNA processing under stress conditions are poorly understood. This study identifies human NF-κB repressing factor (NKRF) as a HSF1 target gene essential for nucleolar homeostasis during proteotoxic stress. Rather than preventing protein misfolding and/or aggregation, this unconventional stress protein has a critical role in preventing aberrant rRNA precursors and discarded fragment accumulation and directing rRNA processing dynamics. The findings highlight a key aspect of the human cell response to proteotoxic stress, opening new scenarios on ribosome biogenesis regulation.</jats:p>