| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Ihiawakrim, Dris
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (21/21 displayed)
- 2024Ultrasonic chemical synthesis of zinc-manganese ferrites with improved magnetic properties.citations
- 2024Tailoring the pore structure of iron oxide core@stellate mesoporous silica shell nanocomposites: effects on MRI and magnetic hyperthermia properties and applicability to anti-cancer therapiescitations
- 2022A detailed investigation of the core@shell structure of exchanged coupled magnetic nanoparticles after performing solvent annealingcitations
- 2022TiO2 supported Co catalysts for the hydrogenation of γ-valerolactone to 2methyltetrahydrofuran: influence of the supportcitations
- 2022Shedding light on functional hybrid nanocomposites 19th century paint mediumcitations
- 2021Versatile template-directed synthesis of gold nanocages with a predefined number of windowscitations
- 2020Quantitative Analysis of the Specific Absorption Rate Dependence on the Magnetic Field Strength in ZnxFe3−xO4 Nanoparticlescitations
- 2020Efficiency of pyoverdines in iron removal from flocking asbestos waste: An innovative bacterial bioremediation strategycitations
- 2019Study by advanced transmission electron microscopy techniques fragile materials
- 2019The effect of basic pH on the elaboration of ZnFe2O4 nanoparticles by co-precipitation method: Structural, magnetic and hyperthermia characterizationcitations
- 2019The effect of basic pH on the elaboration of ZnFe2O4 nanoparticles by co-precipitation method: Structural, magnetic and hyperthermia characterizationcitations
- 2018High pressures pathway toward boron-based nanostructured solidscitations
- 2018High pressures pathway toward boron-based nanostructured solidscitations
- 2016Metal nanoparticle mediated space charge and its optical control in an organic hole-only devicecitations
- 2016Surface plasmon resonance of an individual nano-object on an absorbing substrate : quantitative effects of distance and 3D orientationcitations
- 2016Surface plasmon resonance of an individual nano-object on an absorbing substrate : quantitative effects of distance and 3D orientationcitations
- 2016Advanced three dimensional characterization of silica-based ultraporous materialscitations
- 2014Magnetic Properties of Mono- and Multilayer Assemblies of Iron Oxide Nanoparticles Promoted by SAMscitations
- 2013A single-stage functionalization and exfoliation method for the production of graphene in water: stepwise construction of 2D-nanostructured composites with iron oxide nanoparticlescitations
- 2013A single-stage functionalization and exfoliation method for the production of graphene in water: stepwise construction of 2D-nanostructured composites with iron oxide nanoparticlescitations
- 2012Hexahistidine-Tagged Single-Walled Carbon Nanotubes (His6-tagSWNTs): A Multifunctional Hard Template for Hierarchical Directed Self-Assembly and Nanocomposite Constructioncitations
Places of action
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article
Tailoring the pore structure of iron oxide core@stellate mesoporous silica shell nanocomposites: effects on MRI and magnetic hyperthermia properties and applicability to anti-cancer therapies
Abstract
International audience ; Core–shell nanocomposites made of iron oxide core (IO NPs) coated with mesoporous silica (MS) shells are promising theranostic agents. While the core is being used as an efficient heating nanoagent under alternating magnetic field (AMF) and near infra-red (NIR) light and as a suitable contrast agent for magnetic resonance imaging (MRI), the MS shell is particularly relevant to ensure colloidal stability in a biological buffer and to transport a variety of therapeutics. However, a major challenge with such inorganic nanostructures is the design of adjustable silica structures, especially with tunable large pores which would be useful, for instance, for the delivery of large therapeutic biomolecule loading and further sustained release. Furthermore, the effect of tailoring a porous silica structure on the magneto- or photothermal dissipation still remains poorly investigated. In this work, we undertake an in-depth investigation of the growth of stellate mesoporous silica (STMS) shells around IO NPs cores and of their micro/mesoporous features respectively through time-lapse and in situ liquid phase transmission electron microscopy (LPTEM) and detailed nitrogen isotherm adsorption studies. We found here that the STMS shell features (thickness, pore size, surface area) can be finely tuned by simply controlling the sol–gel reaction time, affording a novel range of IO@STMS core@shell NPs. Finally, regarding the responses under alternating magnetic fields and NIR light which are evaluated as a function of the silica structure, IO@STMS NPs having a tunable silica shell structure are shown to be efficient as T2-weighted MRI agents and as heating agents for magneto- and photoinduced hyperthermia. Furthermore, such IO@STMS are found to display anti-cancer effects in pancreatic cancer cells under magnetic fields (both alternating and rotating).