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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Rudolf, Petra
University of Groningen
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (62/62 displayed)
- 2024Understanding the Surface Chemistry of SnO 2 Nanoparticles for High Performance and Stable Organic Solar Cellscitations
- 2024Solvothermal Synthesis of Rare Earth Bisphthalocyaninescitations
- 2024Solvothermal Synthesis of Rare Earth Bisphthalocyaninescitations
- 2024Understanding the Surface Chemistry of SnO2 Nanoparticles for High Performance and Stable Organic Solar Cellscitations
- 2024Graphene growth from photo-polymerized bi-phenylthiol self-assembled monolayerscitations
- 2024Graphene growth from photo-polymerized bi-phenylthiol self-assembled monolayerscitations
- 2023Temperature-responsive and biocompatible nanocarriers based on clay nanotubes for controlled anti-cancer drug releasecitations
- 2023Temperature-responsive and biocompatible nanocarriers based on clay nanotubes for controlled anti-cancer drug releasecitations
- 2023Electrically Conductive and Highly Stretchable Piezoresistive Polymer Nanocomposites via Oxidative Chemical Vapor Depositioncitations
- 2023Electrically Conductive and Highly Stretchable Piezoresistive Polymer Nanocomposites via Oxidative Chemical Vapor Depositioncitations
- 2023Growth and Characterization of Carbon Nanofibers Grown on Vertically Aligned InAs Nanowires via Chemical Vapour Depositioncitations
- 2023Effect of intermolecular interactions on the glass transition temperature of chemically modified alternating polyketonescitations
- 2023Effect of intermolecular interactions on the glass transition temperature of chemically modified alternating polyketonescitations
- 2023Solvothermal synthesis of lanthanide-functionalized graphene oxide nanocompositescitations
- 2023Solvothermal synthesis of lanthanide-functionalized graphene oxide nanocompositescitations
- 2023Nickel Boride (Ni x B) Nanocrystals:From Solid-State Synthesis to Highly Colloidally Stable Inkscitations
- 2023Nickel Boride (NixB) Nanocrystalscitations
- 2022All-dry, one-step synthesis, doping and film formation of conductive polypyrrolecitations
- 2022All-dry, one-step synthesis, doping and film formation of conductive polypyrrolecitations
- 2022Comparative Study of Various Graphene Oxide Structures as Efficient Drug Release Systems for Ibuprofencitations
- 2021Boosting the Thermoelectric Properties of PEDOTcitations
- 2020New Porous Heterostructures Based on Organo-Modified Graphene Oxide for CO(2)Capturecitations
- 2020New Porous Heterostructures Based on Organo-Modified Graphene Oxide for CO(2)Capturecitations
- 2019Chemical Solution Deposition of Ordered 2D Arrays of Room-Temperature Ferrimagnetic Cobalt Ferrite Nanodotscitations
- 2018Electrically-Responsive Reversible Polyketone/MWCNT Network through Diels-Alder Chemistrycitations
- 2018Iron-substituted cubic silsesquioxane pillared clayscitations
- 2018Iron-substituted cubic silsesquioxane pillared clays:Synthesis, characterization and acid catalytic activitycitations
- 2018Magnetic functionality of thin film perovskite hybridscitations
- 2018Thermally induced chemical evolution in polyimide films investigated by X-ray photoelectron spectroscopycitations
- 2018Electrically-responsive reversible Polyketone/MWCNT network through Diels-Alder chemistrycitations
- 2016Band gap narrowing of Sns2 superstructures with improved hydrogen productioncitations
- 2016Band gap narrowing of SnS2 superstructures with improved hydrogen productioncitations
- 2016Mechanical, thermal and decomposition behavior of poly(epsilon-caprolactone) nanocomposites with clay-supported carbon nanotube hybridscitations
- 2015Comparing graphene growth on Cu(111) versus oxidized Cu(111)citations
- 2015Effect of surface reactions on steel, Al2O3 and Si3N4counterparts on their tribological performance with polytetrafluoroethylene filled compositescitations
- 2015Comparing Graphene Growth on Cu(111) versus Oxidized Cu(111)citations
- 2015Comparing Graphene Growth on Cu(111) versus Oxidized Cu(111)citations
- 2014Self-Assembly of Ferromagnetic Organic–Inorganic Perovskite-Like Filmscitations
- 2014Self-Assembly of Ferromagnetic Organic–Inorganic Perovskite-Like Filmscitations
- 2011Surface electronic and structural properties of nanostructured titanium oxide grown by pulsed laser depositioncitations
- 2011Spectroscopy and structural properties of amorphous and nanocrystalline silicon carbide thin filmscitations
- 2010A two-dimensional magnetic hybrid material based on intercalation of a cationic Prussian blue analog in montmorillonite nanoclaycitations
- 2010A Langmuir-Schaefer approach for the synthesis of highly ordered organoclay thin filmscitations
- 2009Effects of Acetate on Cation Exchange Capacity of a Zn-Containing Montmorillonitecitations
- 2009Key role of molecular kinetic energy in early stages of pentacene island growthcitations
- 2008Low band gap and ionic bonding with charge transfer, threshold in the polymeric lithium fulleride Li(4)C(60)citations
- 2008Cross-linking of multiwalled carbon nanotubes with polymeric aminescitations
- 2008Formation of carbon nanotubes on iron/cobalt oxides supported on zeolite-Ycitations
- 2008Photochromism and electrochemistry of a dithienylcyclopentene electroactive polymercitations
- 2008Photochromism and electrochemistry of a dithienylcyclopentene electroactive polymercitations
- 2007Characterization by X-ray photoemission spectroscopy of the open and closed forms of a dithienylethene switch in thin filmscitations
- 2006X-ray photoemission spectroscopy study on the effects of functionalization in fulleropyrrolidine and pyrrolidine derivativescitations
- 2006Clay-fulleropyrrolidine nanocompositescitations
- 2006Adsorption of fumaramide [2]rotaxane and its components on a solid substrate:A coverage-dependent studycitations
- 2006Adsorption of fumaramide [2]rotaxane and its components on a solid substratecitations
- 2005Nanostructured CNx (0 <x <0.2) films grown by supersonic cluster beam depositioncitations
- 2004Sealing of porous low-k dielectricscitations
- 2004Insulating surface layer on single crystal K3C60citations
- 2003Sealing of porous low-k dielectrics:an ellipsometric porosimetry study of UV-O3 oxidized SiOxCy filmscitations
- 2002Adsorption of a benzylic amide macrocycle on a solid substratecitations
- 2002Adsorption of a benzylic amide macrocycle on a solid substrate:XPS and HREELS characterization of thin films grown on Au(111)citations
- 2001A high resolution electron energy loss spectroscopy study of the adsorption of benzylic amide macrocycle on Au(111)citations
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article
Temperature-responsive and biocompatible nanocarriers based on clay nanotubes for controlled anti-cancer drug release
Abstract
Administration of temperature-responsive drug carriers that release anticancer drugs at high temperatures can benefit hyperthermia therapies because of the synergistic effect of anticancer drug molecules and high temperature on killing the cancer cells. In this study, we design and characterize a new temperature-responsive nanocarrier based on a naturally occurring and biocompatible clay mineral, halloysite nanotubes. Poly(N-isopropylacrylamide) brushes were grown on the surface of halloysite nanotubes using a combination of mussel-inspired dopamine polymerization and surface-initiated atom transfer radical polymerization. The chemical structure of the hybrid materials was investigated using X-ray photoelectron spectroscopy, thermogravimetric analysis and energy-dispersive X-ray spectroscopy. The hybrid material was shown to have a phase transition temperature of about 32 °C, corresponding to a 40 nm thick polymer layer surrounding the nanotubes. Cell studies suggested that grafting of poly(N-isopropylacrylamide) brushes on the polydopamine-modified halloysite nanotubes suppresses the cytotoxicity caused by the polydopamine interlayer and drug release studies on nanotubes loaded with doxorubicin showed that thanks to the poly(N-isopropylacrylamide) brushes a temperature-dependent drug release is observed. Finally, a fluorescent dye molecule was covalently attached to the polymer-grafted nanotubes and stimulated emission depletion nanoscopy was used to confirm the internalization of the nanotubes in HeLa cells.