| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Viau, Lydie
Institut UTINAM
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (12/12 displayed)
- 2023Copper(I) iodide coordination polymers with triazole substituted pyridine ligands: photophysical and electrical conductivity propertiescitations
- 2023Copper(I) iodide coordination polymers with triazole substituted pyridine ligands: photophysical and electrical conductivity propertiescitations
- 2023A novel conductometric sensor for acetone detection prepared through electro-polymerization of pyrrole-tailed ionic liquid
- 2022Strengthening adhesion of polycarbazole films on ITO surface by covalent electrografting of monomercitations
- 2021Crystal structure of the two-dimensional coordination polymer poly[di-μ-bromido-bis(μ-tetrahydrothiophene)dicopper(I)]citations
- 2020Drug delivery system obtained by hot-melt processing of zein plasticized by a pharmaceutically active ionic liquidcitations
- 2020Inkjet Printable ZnO/PEDOT:PSS Heterojunction for Thin Flexible Semi-Transparent Optoelectronic Sensorscitations
- 2014Full characterization of polypyrrole thin films electrosynthesized in room temperature ionic liquid, water or acetonitrilecitations
- 2014Single-ion conductor nanocomposite organic–inorganic hybrid membranes for lithium batteriescitations
- 2006Optically tunable nonlinearities in polymers based on photoisomerizable metal-based coordination complexescitations
- 2006Optically tunable nonlinearities in polymers based on photoisomerizable metal-based coordination complexescitations
- 2004All-Optical Orientation of Photoisomerizable Octupolar Zinc(II) Complexes in Polymer Filmscitations
Places of action
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article
Drug delivery system obtained by hot-melt processing of zein plasticized by a pharmaceutically active ionic liquid
Abstract
Zein-based filaments containing 20 weight% [Lidocainium][Ibuprofenate] used as a doublyActive Pharmaceutical Ingredient-Ionic Liquid (API-IL) were obtained by extrusion at 130°C.The plasticizing effect of the active ingredient on the zein amorphous matrix was assessed byDifferential Scanning Calorimetry, with the decrease of the glass transition temperature (Tg) from 77°C, for the raw zein, to 53°C. After storage under standard conditions (relative humidity59%, 20°C) the extrudates were rigid, with a high storage modulus (E′) at ambient temperatureof about 3 GPa. They had a main mechanical relaxation (Tα) beginning at 55°C and leading totheir flowing at temperature above 130°C, as determined by Dynamic Mechanical Analysis,with E′ below 1 MPa and tanδ above 1. Their structure was evaluated by Wide Angle X-rayScattering and NMR analyses were used to evaluate the API-IL stability that was shown afterthermomechanical processing. Release experiments performed under simulated physiologicalconditions on filaments evidenced a release of 85% after 7 days immersion. These resultsdemonstrate the interest of using an API-IL to act as plasticizer for a resorbable biopolymer. 2 The resulting material can be shaped by continuous thermomechanical process and used as drugdelivery system.