| People | Locations | Statistics |
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| Naji, M. |
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| Motta, Antonella |
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| Aletan, Dirar |
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| Mohamed, Tarek |
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| Ertürk, Emre |
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| Taccardi, Nicola |
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| Kononenko, Denys |
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| Petrov, R. H. | Madrid |
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| Alshaaer, Mazen | Brussels |
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| Bih, L. |
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| Casati, R. |
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| Muller, Hermance |
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| Kočí, Jan | Prague |
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| Šuljagić, Marija |
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| Kalteremidou, Kalliopi-Artemi | Brussels |
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| Azam, Siraj |
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| Ospanova, Alyiya |
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| Blanpain, Bart |
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| Ali, M. A. |
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| Popa, V. |
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| Rančić, M. |
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| Ollier, Nadège |
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| Azevedo, Nuno Monteiro |
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| Landes, Michael |
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| Rignanese, Gian-Marco |
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Visai, Livia
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (23/23 displayed)
- 2024Electron Beam Powder Bed Fusion of Ti-48Al-2Cr-2Nb Open Porous Scaffold for Biomedical Applications: Process Parameters, Adhesion, and Proliferation of NIH-3T3 Cellscitations
- 2023Enhanced in vitro immersion behavior and antibacterial activity of NiTi orthopedic biomaterial by HAp-Nb2O5 composite depositscitations
- 2023Enhanced in vitro immersion behavior and antibacterial activity of NiTi orthopedic biomaterial by HAp-Nb2O5 composite depositscitations
- 2022Progress in Niobium Oxide-Containing Coatings for Biomedical Applications: A Critical Reviewcitations
- 2021Promising bioglasses for medical applications
- 2020Controlled Release of Thymol From Poly(Lactic Acid)-Based Silver Nanocomposite Films With Antibacterial and Antioxidant Activitycitations
- 2020Controlled Release, Disintegration, Antioxidant, and Antimicrobial Properties of Poly (Lactic Acid)/Thymol/Nanoclay Compositescitations
- 2020Controlled Release of Thymol from Poly(Lactic Acid)-Based Silver Nanocomposite Films with Antibacterial and Antioxidant Activitycitations
- 2018Influence of the nanofiber chemistry and orientation of biodegradable poly(butylene succinate)-based scaffolds on osteoblast differentiation for bone tissue regenerationcitations
- 2017Cellulose nanocrystals as templates for cetyltrimethylammonium bromide mediated synthesis of Ag nanoparticles and their novel use in PLA filmscitations
- 2016From micro- to nanostructured implantable device for local anesthetic deliverycitations
- 2016Antimicrobial properties and cytocompatibility of PLGA/Ag nanocompositescitations
- 2014The Interaction of Bacteria with Engineered Nanostructured Polymeric Materials: A Reviewcitations
- 2014Antibiofilm activity of a monolayer of silver nanoparticles anchored to an amino-silanized glass surfacecitations
- 2014The interaction of bacteria with engineered nanostructured polymeric materials: a review.citations
- 2013Combined effects of Ag nanoparticles and oxygen plasma treatment on PLGA morphological, chemical, and antibacterial properties.citations
- 2012Multifunctional bionanocomposite films of poly(lactic acid), cellulose nanocrystals and silver nanoparticlescitations
- 2012New multifunctional poly(lactide acid) composites: Mechanical, antibacterial, and degradation propertiescitations
- 2011Increasing the antibacterial effect of lysozyme byimmobilization on multiwalled carbon nanotubes.citations
- 2011Bone reconstruction: Au nanocomposite bioglasses with antibacterial propertiescitations
- 2010BIODEGRADABLE PLGA MATRIX NANOCOMPOSITE WITH SILVER NANOPARTICLES:MATERIAL PROPERTIES AND BACTERIA ACTIVITY
- 2009SiO2-P2O5-CaO glasses and glass-ceramics with and without ZnO: relationships among composition, microstructure, and bioactivitycitations
- 2006Antibacterial activity of zinc modified titanium oxide surface
Places of action
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article
Influence of the nanofiber chemistry and orientation of biodegradable poly(butylene succinate)-based scaffolds on osteoblast differentiation for bone tissue regeneration
Abstract
<p>Innovative nanofibrous scaffolds have attracted considerable attention in bone tissue engineering, due to their ability to mimic the hierarchical architecture of an extracellular matrix. Aiming at investigating how the polymer chemistry and fiber orientation of electrospun scaffolds (ES) based on poly(butylene succinate) (PBS) and poly(butylene succinate/diglycolate) (P(BS80BDG20)) affect human osteoblast differentiation, uniaxially aligned (a-) and randomly (r-) distributed nanofibers were produced. Although human osteoblastic SAOS-2 cells were shown to be viable and adherent onto all ES materials, a-P(BS80BDG20) exhibited the best performance both in terms of cellular phosphorylated focal adhesion kinase expression and in terms of alkaline phosphatase activity, calcified bone matrix deposition and quantitative gene expression of bone specific markers during differentiation. It has been hypothesized that the presence of ether linkages may lead to an increased density of hydrogen bond acceptors along the P(BS80BDG20) backbone, which, by interacting with cell membrane components, can in turn promote a better cell attachment on the copolymer mats with respect to the PBS homopolymer. Furthermore, although displaying the same chemical structure, r-P(BS80BDG20) scaffolds showed a reduced cell attachment and osteogenic differentiation in comparison with a-P(BS80BDG20), evidencing the importance of nanofiber alignment. Thus, the coupled action of polymer chemical structure and nanofiber alignment played a significant role in promoting the biological interaction.</p>