• Shiddiky, Muhammad J. A.
• Carrascosa, Laura G.
• Mahler, Stephen M.
• Raftery, Lyndon J.
• Grewal, Yadveer S.
• Howard, Christopher B.
• Thurecht, Kristofer J.
• Trau, Matt
• Jones, Martina L.

Abstract

<p>Whilst recent advances in nanotechnology have yielded many new biosensing capabilities, innovative biological attachment and detection modalities remain relatively underdeveloped. Bi-specific antibodies (bsAbs) - which exhibit binding capability for two separate targets - offer an inherent advantage over conventional antibody reagents by significantly simplifying sensor surface preparation. Herein, we report the deployment of bsAbs for simultaneous attachment to a polymer-coated transducer and label-free, electrochemical (EC) detection of target antigens.</p>

Topics

• surface
• polymer