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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Romero, Luis Emerson Coy
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (35/35 displayed)
- 2019Enhanced electrocatalytic performance triggered by atomically bridged boron nitride between palladium nanoparticles and carbon fibers in gas-diffusion electrodescitations
- 2019Low-temperature growth of epitaxial Ti <inf>2</inf> AlC MAX phase thin films by low-rate layer-by-layer PVDcitations
- 2019Photoelectrochemically Active N-Adsorbing Ultrathin TiO <inf>2</inf> Layers for Water-Splitting Applications Prepared by Pyrolysis of Oleic Acid on Iron Oxide Nanoparticle Surfaces under Nitrogen Environmentcitations
- 2019Dendrimer based theranostic nanostructures for combined chemo- and photothermal therapy of liver cancer cells in vitrocitations
- 2019Effect of porous silicon substrate on structural, mechanical and optical properties of MOCVD and ALD ruthenium oxide nanolayerscitations
- 2019Multilayer design of crN/MoN superhard protective coatings and their characterisationcitations
- 2018Influence of ZnO/graphene nanolaminate periodicity on their structural and mechanical propertiescitations
- 2018Experimental and theoretical studies of the physicochemical and mechanical properties of multi-layered TiN/SiC films: Temperature effects on the nanocomposite structurecitations
- 2018Novel and Facile Route for the Synthesis of Tunable Boron Nitride Nanotubes Combining Atomic Layer Deposition and Annealing Processes for Water Purificationcitations
- 2018Synthesis of functional ceramic supports by ice templating and atomic layer depositioncitations
- 2018Structural and mechanical characterization of (TiZrNbHfTa)N/WN multilayered nitride coatingscitations
- 2018Cilostazol-Loaded Poly(ε-Caprolactone) Electrospun Drug Delivery System for Cardiovascular Applicationscitations
- 2018Microstructure, phase composition and mechanical properties of novel nanocomposite (TiAlSiY)N and nano-scale (TiAlSiY)N/MoN multifunctional heterostructurescitations
- 2018A new type of (TiZrNbTaHf)N/MoN nanocomposite coating: Microstructure and properties depending on energy of incident ionscitations
- 2018Cyclodextrin-based magnetic nanoparticles for cancer therapycitations
- 2018Nano-multilayered coatings of (TiAlSiY)N/MeN (Me=Mo, Cr and Zr): Influence of composition of the alternating layer on their structural and mechanical propertiescitations
- 2018Gel with silver and ultrasmall iron oxide nanoparticles produced with Amanita muscaria extract: physicochemical characterization, microstructure analysis and anticancer propertiescitations
- 2018High-temperature Magnetodielectric Bi (Fe0.5Mn0.5) O3 Thin Films with Checkerboard-Ordered Oxygen Vacancies and Low Magnetic Dampingcitations
- 2018ZnS coating for enhanced environmental stability and improved properties of ZnO thin filmscitations
- 2018Superhard CrN/MoN coatings with multilayer architecturecitations
- 2017Nanoscale Effects of Radiation (UV, X-ray, and γ) on Calcite Surfaces: Implications for its Mechanical and Physico-Chemical Propertiescitations
- 2017Release and cytotoxicity studies of magnetite/Ag/antibiotic nanoparticles: An interdependent relationshipcitations
- 2017Perpendicularly magnetized Co20Fe60B20 layer sandwiched between Au with low Gilbert dampingcitations
- 2017Mechanical properties of boron nitride thin films prepared by atomic layer depositioncitations
- 2017High Electrocatalytic Response of a Mechanically Enhanced NbC Nanocomposite Electrode Toward Hydrogen Evolution Reactioncitations
- 2017Boron Nitride Nanoporous Membranes with High Surface Charge by Atomic Layer Depositioncitations
- 2016Combined reactive/non-reactive DC magnetron sputtering of high temperature composite AlN-TiB <inf>2</inf> -TiSi <inf>2</inf>citations
- 2016Poly(ethylene oxide)-block-polystyrene thin films morphology controlled by drying conditions and substrate topographycitations
- 2016Enhancement of optical and mechanical properties of Si nanopillars by ALD TiO<inf>2</inf>coatingcitations
- 2016Gradient nanostructured coatings obtained by magnetron sputtering of a multiphase AlN–TiB<inf>2</inf>–TiSi<inf>2</inf> targetcitations
- 2016Fourier transform infrared and Raman spectroscopy studies on magnetite/Ag/antibiotic nanocompositescitations
- 2016Orientation dependent Ti diffusion in YNMO/STO thin films deposited by pulsed laser depositioncitations
- 2016High temperature behavior of functional TiAlBSiN nanocomposite coatingscitations
- 2015Tuning the photodynamic efficiency of TiO<inf>2</inf> nanotubes against HeLa cancer cells by Fe-dopingcitations
- 2014Facile synthesis of highly stable and water-soluble magnetic MWCNT/α-Fe nanocompositescitations
Places of action
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article
Tuning the photodynamic efficiency of TiO<inf>2</inf> nanotubes against HeLa cancer cells by Fe-doping
Abstract
<p>In this study Fe-doped TiO<sub>2</sub> (0.35 to 3.50 wt% Fe) nanotubes (NTs) were prepared as the potential photosensitizer for near-visible light driven photodynamic therapy (PDT) against cervical cancer cells (HeLa). Characterization of the prepared nanotubes by X-ray diffraction (XRD), Raman spectroscopy and X-ray photoelectron spectroscopy (XPS) confirmed the successful incorporation of Fe<sup>3+</sup> as a dopant into the TiO<sub>2</sub> matrix, which was mainly composed of an anatase phase, while elemental mapping using energy dispersive X-ray spectroscopy (EDX) showed homogenous distribution of the dopant ions in TiO<sub>2</sub> for both low and high doping levels. UV-Vis studies showed that Fe doping in TiO<sub>2</sub> increases the light absorption within the visible range, particularly in the case of 0.70 and 1.40 wt% Fe-TiO<sub>2</sub> and provides additional energy levels within the band gap, which promotes the photo-excited charge transport towards the conduction band. Photo-cytotoxic activity of the prepared Fe-doped TiO<sub>2</sub> NTs was investigated in vitro against cervical cancer cells (HeLa) and compared with human normal fibroblasts (GM07492). Fe-doped TiO<sub>2</sub> NTs exhibited no or lower dark cytotoxicity than un-doped TiO<sub>2</sub> NTs, which confirms their superior biocompatibility. Under the near-visible light irradiation (∼405 nm) Fe-doped TiO<sub>2</sub> NTs showed higher photo-cytotoxic efficiency than un-doped TiO<sub>2</sub> NTs, which was found to be dependent on the NTs concentration, but not on the incubation time of cells after near-visible light irradiation. The highest activity was observed for 0.70 and 1.40 wt% Fe-TiO<sub>2</sub> NTs. Fluorescent labeling of treated HeLa cells showed distinct morphological changes, particularly in the perimitochondrial area suggesting a mitochondria-involved apoptosis of cells, but also the nuclei and cytoskeleton were subject to Fe-TiO<sub>2</sub> NTs induced photo-damage. Apoptosis of PDT treated HeLa cells was also confirmed using ethidium homodimer (EthD-1).</p>