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Naji, M. |
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Motta, Antonella |
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Aletan, Dirar |
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Mohamed, Tarek |
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Ertürk, Emre |
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Taccardi, Nicola |
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Kononenko, Denys |
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Petrov, R. H. | Madrid |
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Alshaaer, Mazen | Brussels |
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Bih, L. |
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Casati, R. |
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Muller, Hermance |
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Kočí, Jan | Prague |
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Šuljagić, Marija |
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Kalteremidou, Kalliopi-Artemi | Brussels |
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Azam, Siraj |
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Ospanova, Alyiya |
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Blanpain, Bart |
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Ali, M. A. |
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Popa, V. |
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Rančić, M. |
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Ollier, Nadège |
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Azevedo, Nuno Monteiro |
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Landes, Michael |
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Rignanese, Gian-Marco |
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Tremel, Wolfgang
University of Münster
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (33/33 displayed)
- 2023Bandgap engineering of melon using highly reduced graphene oxide for enhanced photoelectrochemical hHydrogen evolution
- 2021A generalized method for high-speed fluorination of metal oxides by spark plasma sintering yields Ta3O7F and TaO2F with high photocatalytic activity for oxygen evolution from water
- 2021Insights into the In Vitro Formation of Apatite from Mg‐Stabilized Amorphous Calcium Carbonatecitations
- 2020Monitoring a Mechanochemical Reaction Reveals the Formation of a New ACC Defect Variant Containing the HCO 3 – Anion Encapsulated by an Amorphous Matrixcitations
- 2020Monitoring a Mechanochemical Reaction Reveals the Formation of a New ACC Defect Variant Containing the HCO$_{3}$ $^{-}$ Anion Encapsulated by an Amorphous Matrixcitations
- 2018Robustness of elastic properties in polymer nanocomposite films examined over the full volume fraction rangecitations
- 2018From Single Molecules to Nanostructured Functional Materialscitations
- 2017Polypropylene-based melt mixed composites with singlewalled carbon nanotubes for thermoelectric applications: Switching from p-type to n-type by the addition of polyethylene glycolcitations
- 2017Direction-dependent elastic properties and phononic behavior of PMMA/BaTiO3 nanocomposite thin filmscitations
- 2017Snapshots of calcium carbonate Formation - a step by step analysiscitations
- 2016Correlation of epoxy material properties with the toughening effect of fullerene-like WS 2 nanoparticlescitations
- 2016Hierachical Ni@Fe2O3 superparticles through epitaxial growth of gamma-Fe2O3 nanorods on in situ formed Ni nanoplatescitations
- 2015Siliceous spicules enhance fracture-resistance and stiffness of pre-colonial Amazonian ceramicscitations
- 2014Rational assembly and dual functionalization of Au@MnO heteroparticles on TiO2 nanowirescitations
- 2014Carbon-coated anatase TiO2 nanotubes for Li- and Na-ion anodes
- 2013Graphene-type sheets of Nb1-xWxS2citations
- 2012Vanadium pentoxide nanoparticles mimic vanadium haloperoxidases and thwart biofilm formationcitations
- 2012Multifunctional superparamagnetic MnO@SiO2 core/shell nanoparticles and their application for optical and magnetic resonance imagingcitations
- 2011Strong Stabilization of Amorphous Calcium Carbonate Emulsion by Ovalbumin: Gaining Insight into the Mechanism of 'Polymer-Induced Liquid Precursor' Processescitations
- 2011Strong stabilization of amorphous calcium carbonate emulsion by ovalbumin: gaining insight into the mechanism of 'polymer-induced liquid precursor' processes.citations
- 2011Carbonate-coordinated metal complexes precede the formation of liquid amorphous mineral emulsions of divalent metal carbonatescitations
- 2011Hydrogen peroxide sensors for cellular imaging based on horse radish peroxidase reconstituted on polymer-functionalized TiO2 nanorodscitations
- 2010Formation of silicones mediated by the sponge enzyme silicatein-alphacitations
- 2009Evidence for biogenic processes during formation of ferromanganese crusts from the Pacific Oceancitations
- 2008Early homogenous amorphous precursor stages of calcium carbonate and subsequent crystal growth in levitated dropletscitations
- 2008Bioencapsulation of living bacteria (Escherichia coli) with poly(silicate) After transformation with silicatein-alpha genecitations
- 2008Reply to "Mirror Symmetry Breaking" of the centrosymmetric CaCO3 crystals with amino acidscitations
- 2008Nucleation and growth of CaCO(3) mediated by the egg-white protein ovalbumin: A time-resolved in situ study using small-angle neutron scatteringcitations
- 2008Poly(silicate)-metabolizing silicatein in siliceous spicules and silicasomes of demosponges comprises dual enzymatic activities (silica polymerase and silica esterase)citations
- 2007Phase selection of calcium carbonate through the chirality of adsorbed amino acidscitations
- 2007Formation of giant spicules in the deep-sea hexactinellid Monorhaphis chuni (Schulze 1904): electron-microscopic and biochemical studiescitations
- 2007Phasenselektion von Calciumcarbonat durch die Chiralität adsorbierter Aminosäurencitations
- 2005Crystal structure, magnetic properties, and 57Fe Mössbauer spectroscopy of the two-dimensional coordination polymers [M(1,2-bis(1,2,4-triazol-4-yl)ethane)2(NCS)2] (MII = Fe, Co).citations
Places of action
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article
Multifunctional superparamagnetic MnO@SiO2 core/shell nanoparticles and their application for optical and magnetic resonance imaging
Abstract
<p>Highly biocompatible multifunctional nanocomposites consisting of monodisperse manganese oxide nanoparticles with luminescent silica shells were synthesized by a combination of w/o-microemulsion techniques and common sol-gel procedures. The nanoparticles were characterized by TEM analysis, powder XRD, SQUID magnetometry, FT-IR, UV/vis and fluorescence spectroscopy and dynamic light scattering. Due to the presence of hydrophilic poly(ethylene glycol) (PEG) chains on the SiO2 surface, the nanocomposites are highly soluble and stable in various aqueous solutions, including physiological saline, buffer solutions and human blood serum. The average number of surface amino groups available for ligand binding on the particles was determined using a colorimetric assay with fluorescein isothiocyanate (FITC). This quantification is crucial for the drug loading capacity of the nanoparticles. SiO2 encapsulated MnO@SiO2 nanoparticles were less prone to Mn-leaching compared to nanoparticles coated with a conventional bi-functional dopamine PEG ligand. The presence of a silica shell did not change the magnetic properties significantly, and therefore, the MnO@SiO2 nanocomposite particles showed a T-1 contrast with relaxivity values comparable to those of PEGylated MnO nanoparticles. The cytotoxicity of the MnO@SiO2-PEG/NH2 nanoparticles was evaluated using primary cells of the innate immune system with bone marrow-derived polymorphonuclear neutrophils (BM-PMNs) as import phagocytes in the first line of defence against microbial pathogens, and bone marrow-derived dendritic cells (BMDCs), major regulators of the adaptive immunity. MnO@SiO2-PEG/NH2 nanoparticles have an acceptable toxicity profile and do not interact with BMDCs as shown by the lack of activation and uptake.</p>